Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Uta C. Hoppe"'
Autor:
Albert Topf, Karl Sotlar, Matthias Hackl, Theo Kraus, Vera Paar, Simon Watzinger, Achim Aigner, Uta C. Hoppe, Rudin Pistulli, Moritz Mirna, Rer Nat Alexander Ewe, Bruno K. Podesser, Assoc Prof Michael Lichtenauer, Attila Kiss
Publikováno v:
Cardiovascular Research. 118:556-572
Aims Myocarditis is associated with formidable symptoms and increased risk of adverse outcomes. Current approaches mostly rely on symptomatic treatments, warranting novel concepts for clinical practice. The aim of this study was to investigate the mi
Autor:
Miriam Eber, Vera Paar, Michael Lichtenauer, Moritz Mirna, Christian Jung, Richard Rezar, Uta C. Hoppe, Albert Topf
Publikováno v:
Cells, Vol 8, Iss 11, p 1352 (2019)
Cells
Cells
Background: MicroRNAs (miRNAs) are small, single-stranded RNA sequences that regulate gene expression on a post-transcriptional level. In the last few decades, various trials have investigated the diagnostic and therapeutic potential of miRNAs in sev
Autor:
Peter Jirak, Naufal Zagidullin, Robert Larbig, Mathias C. Brandt, Lukas J. Motloch, Michael Lichtenauer, Uta C. Hoppe, Vera Paar
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 21, p 5304 (2019)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
Cardiac arrhythmias constitute a major health problem with a huge impact on mortality rates and health care costs. Despite ongoing research efforts, the understanding of the molecular mechanisms and processes responsible for arrhythmogenesis remains
Autor:
Peter, Jirak, Lars, Stechemesser, Elena, Moré, Michael, Franzen, Albert, Topf, Moritz, Mirna, Vera, Paar, Rudin, Pistulli, Daniel, Kretzschmar, Bernhard, Wernly, Uta C, Hoppe, Michael, Lichtenauer, Hermann, Salmhofer
Publikováno v:
Advances in clinical chemistry. 89
Fetuin-A, also termed alpha2-Heremans-Schmid glycoprotein, is a 46kDa hepatocyte derived protein (hepatokine) and serves multifaceted functions.
Autor:
Bernhard Wernly, Vera Paar, Moritz Mirna, Uta C. Hoppe, Theo Kraus, Michael Lichtenauer, Karl Sotlar, Rudin Pistulli
Publikováno v:
European Journal of Clinical Investigation
Background Experimental autoimmune myocarditis (EAM) is a common animal model for the investigation of the pathophysiology of myocarditis. Because of diverging findings from previous studies, we performed serial echocardiographic examinations through
Publikováno v:
The Journal of Membrane Biology
Mitochondrial Ca(2+) uptake (mCa(2+) uptake) is thought to be mediated by the mitochondrial Ca(2+) uniporter (MCU). UCP2 and UCP3 belong to a superfamily of mitochondrial ion transporters. Both proteins are expressed in the inner mitochondrial membra
Autor:
Bruno K. Podesser, Christian Jung, Michael Lichtenauer, Matthias Hackl, Martin Förster, Attila Kiss, Josefina Piñón Hofbauer, Achim Aigner, Bernhard Wernly, Theo Kraus, Vera Paar, Patrick M. Pilz, M. Wimmer, Uta C. Hoppe, Lukas J. Motloch, B. Tockner
Publikováno v:
Cells
Volume 9
Issue 2
Cells, Vol 9, Iss 2, p 295 (2020)
Volume 9
Issue 2
Cells, Vol 9, Iss 2, p 295 (2020)
Introduction: Antibody treatment with anti-thymocyte globulin (ATG) has been shown to be cardioprotective. We aimed to evaluate which single anti-T-cell epitope antibody alters chemokine expression at a level similar to ATG and identified CD3, which
Autor:
Juejin, Wang, Guang, Li, Dejie, Yu, Yuk Peng, Wong, Tan Fong, Yong, Mui Cheng, Liang, Ping, Liao, Roger, Foo, Uta C, Hoppe, Tuck Wah, Soong
Publikováno v:
Channels
Recently, we reported that homozygous deletion of alternative exon 33 of CaV1.2 calcium channel in the mouse resulted in ventricular arrhythmias arising from increased CaV1.2Δ33 ICaL current density in the cardiomyocytes. We wondered whether heteroz
Autor:
Guang, Li, Juejin, Wang, Ping, Liao, Peter, Bartels, Hengyu, Zhang, Dejie, Yu, Mui Cheng, Liang, Kian Keong, Poh, Chye Yun, Yu, Fengli, Jiang, Tan Fong, Yong, Yuk Peng, Wong, Zhenyu, Hu, Hua, Huang, Guangqin, Zhang, Mary Joyce, Galupo, Jin-Song, Bian, Sathivel, Ponniah, Scott Lee, Trasti, Kelvin, See, Roger, Foo, Uta C, Hoppe, Stefan, Herzig, Tuck Wah, Soong
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 114(21)
To directly address in vivo significance of the altered CaV1.2 channel property arising from alternative splicing, we generated CaV1.2 exon 33-specific knockout (exon 33−/−) mice. Here, we showed that the exclusion of alternative exon 33 altered
Autor:
Robert, Larbig, Sara, Reda, Vera, Paar, Andrea, Trost, Johannes, Leitner, Stephanie, Weichselbaumer, Karolina A, Motloch, Bernhard, Wernly, Andreas, Arrer, Benjamin, Strauss, Michael, Lichtenauer, Herbert A, Reitsamer, Lars, Eckardt, Guiscard, Seebohm, Uta C, Hoppe, Lukas J, Motloch
Publikováno v:
Experimental physiology. 102(6)
What is the central question of this study? Knockdown of UCP2 reduces mitochondrial Ca