Zobrazeno 1 - 10
of 88
pro vyhledávání: '"Ulf Hedin"'
Autor:
Marion J.J. Gijbels, Judith C. Sluimer, Ulf Hedin, Christoph Kuppe, J. De Bruijn, Thomas L. Theelen, Javier Perales-Patón, Rafael Kramann, Peter Carmeliet, Barend Mees, Leon J. Schurgers, Chris P. M. Reutelingsperger, E. Biessen, Elke Marsch, Andrew H. Baker, Jasper A. F. Demandt, Han Jin, Julio Saez-Rodriguez, K. van Kuijk, Ljubica Perisic Matic
Publikováno v:
Cardiovascular Research, 118(5), 1232-1246
Cardiovascular Research, 118(5), 1232-1246. Oxford University Press
Cardiovascular Research, 118(5), 1232-1246. Oxford University Press
AIMS: Atherosclerotic plaque hypoxia is detrimental for macrophage function. Prolyl hydroxylases (PHDs) initiate cellular hypoxic responses, possibly influencing macrophage function in plaque hypoxia. Thus, we aimed to elucidate the role of myeloid P
Autor:
Urszula Rykaczewska, Quanyi Zhao, Peter Saliba-Gustafsson, Mariette Lengquist, Malin Kronqvist, Otto Bergman, Zhiqiang Huang, Kent Lund, Katarina Waden, Zara Pons Vila, Kenneth Caidahl, Josefin Skogsberg, Vladana Vukojevic, Jan H.N. Lindeman, Joy Roy, Göran K. Hansson, Eckardt Treuter, Nicholas J. Leeper, Per Eriksson, Ewa Ehrenborg, Anton Razuvaev, Ulf Hedin, Ljubica Matic
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology, 42(5), 659-676. LIPPINCOTT WILLIAMS & WILKINS
Background: Understanding the processes behind carotid plaque instability is necessary to develop methods for identification of patients and lesions with stroke risk. Here, we investigated molecular signatures in human plaques stratified by echogenic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bb5442c30ed8817975e0666df3d06a9
https://hdl.handle.net/1887/3566972
https://hdl.handle.net/1887/3566972
Autor:
Mariette Lengquist, Mathilde Frederikke Bjørn Bonde, G. Kees Hovingh, Heidi Engslev Lund, Bidda Rolin, Stefan Zahn, Michael Nyberg, Karin Hultman, Lars Maegdefessel, Valentina Manfè, Pernille Gry Wulff-Larsen, Karin Conde-Knape, Ulf Hedin, Djordje Djordjevic, Rikke Kaae Kirk, Ljubica Perisic Matic, Niels Blume, Günaj Rakipovski, Maj Petersen, Natasha Barascuk
Publikováno v:
Atherosclerosis, 314, 1-9. Elsevier Ireland Ltd
Background and aims Clinical interventions targeting nonlipid risk factors are needed given the high residual risk of atherothrombotic events despite effective control of dyslipidemia. Dickkopf-1 (DKK1) plays a lipid-independent role in vascular path
Autor:
Ulf Hedin, Azadeh Nilchian, Estelle Plant, Malgorzata M Parniewska, Ana Santiago, Aránzazu Rossignoli, Josefin Skogsberg, Ljubica Perisic Matic, Jonas Fuxe
Publikováno v:
The Journal of infectious diseases
The Journal of Infectious Diseases
The Journal of Infectious Diseases
Multiple viruses are implicated in atherosclerosis, but the mechanisms by which they infect cells and contribute to plaque formation in arterial walls are not well understood. Based on reports showing the presence of enterovirus in atherosclerotic pl
Autor:
Xiaohui Wu, Angela Cheng, Thomas Q. de Aguiar Vallim, Elizabeth J. Tarling, Joan Cheng, Lars Maegdefessel, Ulf Hedin, Bethan L. Clifford, Nathalie Pamir, Tamer Sallam
Publikováno v:
Arterioscler Thromb Vasc Biol
Objective: Atherosclerosis is a leading cause of death in developed countries. MicroRNAs act as fine-tuners of gene expression and have been shown to have important roles in the pathophysiology and progression of atherosclerosis. We, and others, prev
Autor:
John Pernow, Till Seime, Jiangning Yang, Ekaterina Chernogubova, Xiaowei Zheng, Sergiu-Bogdan Catrina, Ali Mahdi, Aida Collado, Yahor Tratsiakovich, Lars Maegdefessel, Ulf Hedin, Michael Alvarsson, Tong Jiao, Sampath Narayanan, Hong Jin, Changyan Sun, Hanna Winter, Zhichao Zhou
Red blood cells (RBCs) act as mediators of vascular injury in type 2 diabetes mellitus (T2DM). miR-210 plays a protective role in cardiovascular homeostasis and is decreased in whole blood of T2DM mice. We hypothesized that downregulation of RBC miR-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04c0c73a87d79c7770ad52cd7bec1d92
https://doi.org/10.2337/figshare.16896523
https://doi.org/10.2337/figshare.16896523
Autor:
Gry Freja Skovsted, Catarina Rippe, Karl Swärd, Katarzyna K. Krawczyk, Ulf Hedin, Ljubica Perisic, Jais Oliver Berg, Rasmus Dreier
Publikováno v:
American Journal of Physiology-Cell Physiology. 315:C873-C884
The endothelin type B receptor (ETB or EDNRB) is highly plastic and is upregulated in smooth muscle cells (SMCs) by arterial injury and following organ culture in vitro. We hypothesized that this transcriptional plasticity may arise, in part, because
Autor:
Malgorzata Furmanik, Erik A.L. Biessen, Asim Cengiz Akbulut, Marie-Luce Bochaton-Piallat, Rick H. van Gorp, Guillaume J.J.M. van Eys, Chris P. M. Reutelingsperger, Ulf Hedin, Brecht A. G. Willems, Diane Proudfoot, Leon J. Schurgers, Ljubica Perisic, Harald H.H.W. Schmidt, Catherine M. Shanahan, Barend Mees, Martijn L. Chatrou
Publikováno v:
Circulation Research, 127(7), 911-927. LIPPINCOTT WILLIAMS & WILKINS
Rationale: Vascular calcification, the formation of calcium phosphate crystals in the vessel wall, is mediated by vascular smooth muscle cells (VSMCs). However, the underlying molecular mechanisms remain elusive, precluding mechanism-based therapies.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cde9aba86be792b8cee8841ca3207a9
https://cris.maastrichtuniversity.nl/en/publications/6d2b25f6-9107-4d02-ad2e-fb68748635f8
https://cris.maastrichtuniversity.nl/en/publications/6d2b25f6-9107-4d02-ad2e-fb68748635f8
Autor:
Ying Wang, Nicholas J. Leeper, Philip S. Tsao, Ljubica Perisic Matic, Kai-Uwe Jarr, Lars Maegdefessel, Greg Winski, Shen Lao, Vivek Nanda, Valentina Paloschi, Jianqin Ye, Pavlos Tsantilas, Alyssa M. Flores, Monika Vaerst, Zhiyuan Wu, Yoko Kojima, Hans-Henning Eckstein, Jaroslav Pelisek, Anne V. Eberhard, Ulf Hedin
Publikováno v:
Cardiovasc Res
Aims Atherosclerotic cerebrovascular disease underlies the majority of ischaemic strokes and is a major cause of death and disability. While plaque burden is a predictor of adverse outcomes, plaque vulnerability is increasingly recognized as a driver
Autor:
Mona, Ahmed, Tetyana, Tegnebratt, Thuy A, Tran, Li, Lu, Peter, Damberg, Anton, Gisterå, Laura, Tarnawski, Dianna, Bone, Ulf, Hedin, Per, Eriksson, Staffan, Holmin, Björn, Gustafsson, Kenneth, Caidahl
Publikováno v:
International Journal of Nanomedicine
Background Beyond clinical atherosclerosis imaging of vessel stenosis and plaque morphology, early detection of inflamed atherosclerotic lesions by molecular imaging could improve risk assessment and clinical management in high-risk patients. To iden