Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Tingwang Guo"'
Publikováno v:
Biochemistry and Cell Biology. 100:28-36
Interleukin-1β, a key cytokine in gouty inflammation, is precisely regulated by the NLRP3 inflammasome and NF-κB. Our previous study demonstrated that paeonol suppressed IL-1β production in rats with monosodium urate (MSU)-induced arthritis. Wheth
Publikováno v:
Journal of Neurochemistry. 160:88-99
The mechanisms of brain injury after intracerebral hemorrhage (ICH) involve mass effect-induced primary injury and secondary injury caused by a pathologic response to the hematoma. Considerable attentions have recently been paid to the mechanisms and
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Scientific Reports
Scientific Reports
The mechanical response of brain tissue closely relates to cerebral blood flow and brain diseases. During intracerebral haemorrhage (ICH), a mass effect occurs during the initial bleeding and results in significant tissue deformation. However, fewer
Publikováno v:
International Journal of Pharmaceutics. 566:46-56
Intranasal drug delivery provided an alternative and effective approach for the intervention of an intracerebral hemorrhage (ICH). However, the short retention time at the absorption site and slow drug transport in intranasal gel influence the drug b
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Scientific Reports
Scientific Reports
Mass effect induced by growing hematoma is one of the mechanisms by which intracerebral hemorrhage (ICH) may result in brain injuries. Our goal was to investigate the damage mechanism of hydrostatic pressure associated with mass effect and the cooper
Autor:
Qian Yang, Haijian Xia, Bochu Wang, Wenfeng Li, Tingwang Guo, Ye He, Shilei Hao, Feiyan Gao, Zhongjun Cheng, Ju Wang, Yuhua Gong, Qing Qu, Tiantian Luo
Publikováno v:
International Journal of Pharmaceutics. 534:179-189
The role of surgery for most patients with spontaneous intracerebral haemorrhage (ICH) remains controversial due to the continuous occurrence of postoperative iron overload induced by low clot clearance rate. In this study, human hair keratose hydrog
Publikováno v:
ACS applied materialsinterfaces. 11(20)
In recent years, favorable enhanced wound-healing properties and excellent biocompatibility of keratin derived from human hair have attracted considerable attention. Recombinant keratin proteins can be produced by recombinant DNA technology and have
Publikováno v:
International journal of pharmaceutics. 566
In situ keratin hydrogel offer a promising strategy to relieve the brain injury after intracerebral hemorrhage (ICH) by delivering the iron chelator directly to the stroke site. However, the injectable property of traditional keratin hydrogel is unsa
Publikováno v:
Journal of Materials Science: Materials in Medicine. 30
Keratin has the potential to improve biocompatibility and bioactivity of polymeric nanofibers. However, the addition of keratin into the blend nanofiber would decrease the mechanical properties of nanofibers due to the poor spinnability of keratin, a
Autor:
Zhongjun Cheng, Shilei Hao, Bochu Wang, Xiaoliang Chen, Tingwang Guo, Feiyan Gao, Jingou Ji, Wenfeng Li, Dongliang Zhai
Publikováno v:
Journal of Nanobiotechnology
Journal of Nanobiotechnology, Vol 16, Iss 1, Pp 1-13 (2018)
Journal of Nanobiotechnology, Vol 16, Iss 1, Pp 1-13 (2018)
Background Nanotechnology-based drug delivery systems have been widely used for oral and systemic dosage forms delivery depending on the mucoadhesive interaction, and keratin has been applied for biomedical applications and drug delivery. However, fe