Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Tanja D de Gruijl"'
Publikováno v:
Michielon, E, de Gruijl, T D & Gibbs, S 2022, ' From simplicity to complexity in current melanoma models ', Experimental Dermatology, vol. 31, no. 12, pp. 1818-1836 . https://doi.org/10.1111/exd.14675
Despite the recent impressive clinical success of immunotherapy against melanoma, development of primary and adaptive resistance against immune checkpoint inhibitors remains a major issue in a large number of treated patients. This highlights the nee
Autor:
Hans van Vliet, Paul W. H. I. Parren, Rieneke van de Ven, Jana Vree, Roeland Lameris, Tanja D. de Gruijl, Renate de Boer, Anita G.M. Stam, George L. Scheffer, Arnon P. Kater, Steven T. Pals, Mark-David Levin, Rob C. Roovers, Iris de Weerdt
Publikováno v:
Cancer immunology research, 9(1), 50-61. American Association for Cancer Research Inc.
Cancer Immunology Research, 9(1), 50-61. AMER ASSOC CANCER RESEARCH
de Weerdt, I, Lameris, R, Scheffer, G L, Vree, J, de Boer, R, Stam, A G, van de Ven, R, Levin, M-D, Pals, S T, Roovers, R C, Parren, P W H I, de Gruijl, T D, Kater, A P & van der Vliet, H J 2021, ' A Bispecific Antibody Antagonizes Prosurvival CD40 Signaling and Promotes Vγ9Vδ2 T cell-Mediated Antitumor Responses in Human B-cell Malignancies ', Cancer Immunology Research, vol. 9, no. 1, pp. 50-61 . https://doi.org/10.1158/2326-6066.CIR-20-0138
Cancer Immunology Research, 9(1), 50-61. American Association for Cancer Research Inc.
Cancer Immunology Research, 9(1), 50-61. AMER ASSOC CANCER RESEARCH
de Weerdt, I, Lameris, R, Scheffer, G L, Vree, J, de Boer, R, Stam, A G, van de Ven, R, Levin, M-D, Pals, S T, Roovers, R C, Parren, P W H I, de Gruijl, T D, Kater, A P & van der Vliet, H J 2021, ' A Bispecific Antibody Antagonizes Prosurvival CD40 Signaling and Promotes Vγ9Vδ2 T cell-Mediated Antitumor Responses in Human B-cell Malignancies ', Cancer Immunology Research, vol. 9, no. 1, pp. 50-61 . https://doi.org/10.1158/2326-6066.CIR-20-0138
Cancer Immunology Research, 9(1), 50-61. American Association for Cancer Research Inc.
Novel T cell-based therapies for the treatment of B-cell malignancies, such as chronic lymphocytic leukemia (CLL) and multiple myeloma (MM), are thought to have strong potential. Progress, however, has been hampered by low efficacy and high toxicity.
Autor:
Linde M. Veen, Tim L.P. Skrabanja, Hanneke W. M. van Laarhoven, Maarten F. Bijlsma, Tanja D. de Gruijl, Sarah Derks
Publikováno v:
Veen, L M, Skrabanja, T L P, Derks, S, de Gruijl, T D, Bijlsma, M F & van Laarhoven, H W M 2021, ' The role of transforming growth factor β in upper gastrointestinal cancers : A systematic review ', Cancer Treatment Reviews, vol. 100, 102285 . https://doi.org/10.1016/j.ctrv.2021.102285
Esophageal and gastric malignancies are associated with poor prognosis, in part due to development of recurrences or metastases after curative treatment. The transforming growth factor β (TGF-β) pathway might play a role in the development of treat
Autor:
Kevin, Kos, Muhammad A, Aslam, Rieneke, van de Ven, Max D, Wellenstein, Wietske, Pieters, Antoinette, van Weverwijk, Danique E M, Duits, Kim, van Pul, Cheei-Sing, Hau, Kim, Vrijland, Daphne, Kaldenbach, Elisabeth A M, Raeven, Sergio A, Quezada, Rudi, Beyaert, Heinz, Jacobs, Tanja D, de Gruijl, Karin E, de Visser
Publikováno v:
Cell reports. 38(9)
Breast cancer is accompanied by systemic immunosuppression, which facilitates metastasis formation, but how this shapes organotropism of metastasis is poorly understood. Here, we investigate the impact of mammary tumorigenesis on regulatory T cells (
Autor:
R. Eveline Li, Sjoerd T.T. Schetters, Floortje J. van Haften, Fabrizio Chiodo, Tanja D. de Gruijl, Yvette van Kooyk, Sanne Duinkerken
Publikováno v:
Duinkerken, S, Li, RJE, van Haften, F J, de Gruijl, TD, Chiodo, F, Schetters, STT & van Kooyk, Y 2019, ' Chemically engineered glycan-modified cancer vaccines to mobilize skin dendritic cells ', Current Opinion Chemical Biology, vol. 53, pp. 167-172 . https://doi.org/10.1016/j.cbpa.2019.10.001
Dendritic cell (DC)–targeting vaccines show great promise in increasing antitumor immunity. Glycan-engineered vaccines facilitate both DC targeting and increased uptake by DCs for processing and presentation to CD4+ and CD8+ T cells to induce tumor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49fbeb8814fc80080b2186c39597bd18
https://research.vumc.nl/en/publications/b0f27eba-339e-493e-969c-d95d284c4fd5
https://research.vumc.nl/en/publications/b0f27eba-339e-493e-969c-d95d284c4fd5
Autor:
Dieke van Dinther, Tanja D. de Gruijl, Yvette van Kooyk, Joke M. M. den Haan, Rieneke van de Ven, Dorian A. Stolk
Publikováno v:
van Dinther, D, Stolk, D A, van de Ven, R, van Kooyk, Y, de Gruij, T D & den Haan, J M M 2017, ' Targeting C-type lectin receptors : A high-carbohydrate diet for dendritic cells to improve cancer vaccines ', Journal of Leukocyte Biology, vol. 102, no. 4, pp. 1017-1034 . https://doi.org/10.1189/jlb.5MR0217-059RR
Journal of Leukocyte Biology
Journal of Leukocyte Biology
Review of in vivo targeting of tumor antigens to lectin receptors on antigen-presenting cells using antibodies or ligands may improve the antitumor efficacy of vaccines.
There is a growing understanding of why certain patients do or do not respo
There is a growing understanding of why certain patients do or do not respo
Autor:
Rieneke van de Ven, Tiffany C. Blair, Rom Leidner, Marka R. Crittenden, Tanja D. de Gruijl, David J. Friedman, Shelly Bambina, Yaping Wu, Michael J. Gough, Jason R. Baird, Terry R. Medler, Zhaoyu Sun, Gwen Kramer, R. Bryan Bell, Victoria Troesch
Publikováno v:
Baird, J R, Bryan Bell, R, Troesch, V, Friedman, D, Bambina, S, Kramer, G, Blair, T C, Medler, T, Wu, Y, Sun, Z, de Gruijl, T D, van de Ven, R, Leidner, R S, Crittenden, M R & Gough, M J 2018, ' Evaluation of explant responses to STING ligands: Personalized immunosurgical therapy for head and neck squamous cell carcinoma ', Cancer Research, vol. 78, no. 21, pp. 6308-6319 . https://doi.org/10.1158/0008-5472.CAN-18-1652
Cancer Research, 78(21), 6308-6319. American Association for Cancer Research Inc.
Cancer Research, 78(21), 6308-6319. American Association for Cancer Research Inc.
Surgeons have unique in situ access to tumors enabling them to apply immunotherapies to resection margins as a means to prevent local recurrence. Here, we developed a surgical approach to deliver stimulator of interferon genes (STING) ligands to the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7508ffb1e749659e9c47c89c72a5fdb
https://research.vumc.nl/en/publications/63a98368-5257-4df4-94f3-ee309ecc134c
https://research.vumc.nl/en/publications/63a98368-5257-4df4-94f3-ee309ecc134c
Publikováno v:
Stolk, D, van der Vliet, H J, de Gruijl, T D, van Kooyk, Y & Exley, M A 2018, ' Positive & negative roles of innate effector cells in controlling cancer progression ', Frontiers in Immunology, vol. 9, no. SEP, 1990 . https://doi.org/10.3389/fimmu.2018.01990, https://doi.org/10.3389/fimmu.2018.01990
Frontiers in Immunology
Frontiers in Immunology, Vol 9 (2018)
Frontiers in Immunology
Frontiers in Immunology, Vol 9 (2018)
Innate immune cells are active at the front line of host defense against pathogens and now appear to play a range of roles under non-infectious conditions as well, most notably in cancer. Establishing the balance of innate immune responses is critica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b948f7ec1479f9404e5eb2f0a5f338fb
https://research.vumc.nl/en/publications/bf2541f0-ade6-42b6-be74-2bca39f2096d
https://research.vumc.nl/en/publications/bf2541f0-ade6-42b6-be74-2bca39f2096d
Autor:
Madelon Q, Wentink, Henk M W, Verheul, Arjan W, Griffioen, Kenneth A, Schafer, Susan, McPherson, Richard J, Early, Hans J, van der Vliet, Tanja D, de Gruijl
Publikováno v:
Vaccine. 36(15)
Vascular endothelial growth factor (VEGF) is pivotal in tumor angiogenesis and therapies targeting the VEGF axis are widely used in the clinic for the treatment of cancer. We have developed a therapeutic vaccine targeting human (h)VEGFIn total 54 cyn
Autor:
Anne-Marie Cleton-Jansen, Vincenzo Canzonieri, Monique A. J. van Eijndhoven, Laura Roncuzzi, Sulev Kõks, Tonny Lagerweij, Nicoletta Zini, Massimo Dominici, Maria Pérez-Lanzón, Roberta Bonafede, Tanja D. de Gruijl, Silvia Cervo, Aare Märtson, Nicolas Léveillé, D. Michiel Pegtel, Nicola Baldini, Thomas Wurdinger, Xuan Dung Ho, Agostino Steffan, Katre Maasalu, Ekaterina S. Jordanova, S. Rubina Baglio, Giulia Grisendi, M. Greco, Sonia A. Melo, Sinéad M. Lougheed
Publikováno v:
Clinical Cancer Research, 23(14), 3721-3733. American Association for Cancer Research Inc.
Clinical cancer research, 23(14), 3721-3733. American Association for Cancer Research Inc.
Clinical Cancer Research, 23(14), 3721-3733
Baglio, S R, Lagerweij, T, Pérez-Lanzón, M, Ho, X D, Léveillé, N, Melo, S A, Cleton-Jansen, A M, Jordanova, E S, Roncuzzi, L, Greco, M, Van Eijndhoven, M A J, Grisendi, G, Dominici, M, Bonafede, R, Lougheed, S M, De Gruijl, T D, Zini, N, Cervo, S, Steffan, A, Canzonieri, V, Martson, A, Maasalu, K, Köks, S, Wurdinger, T, Baldini, N & Pegtel, D M 2017, ' Blocking tumor-educated MSC paracrine activity halts osteosarcoma progression ', Clinical Cancer Research, vol. 23, no. 14, pp. 3721-3733 . https://doi.org/10.1158/1078-0432.CCR-16-2726
Clinical cancer research, 23(14), 3721-3733. American Association for Cancer Research Inc.
Clinical Cancer Research, 23(14), 3721-3733
Baglio, S R, Lagerweij, T, Pérez-Lanzón, M, Ho, X D, Léveillé, N, Melo, S A, Cleton-Jansen, A M, Jordanova, E S, Roncuzzi, L, Greco, M, Van Eijndhoven, M A J, Grisendi, G, Dominici, M, Bonafede, R, Lougheed, S M, De Gruijl, T D, Zini, N, Cervo, S, Steffan, A, Canzonieri, V, Martson, A, Maasalu, K, Köks, S, Wurdinger, T, Baldini, N & Pegtel, D M 2017, ' Blocking tumor-educated MSC paracrine activity halts osteosarcoma progression ', Clinical Cancer Research, vol. 23, no. 14, pp. 3721-3733 . https://doi.org/10.1158/1078-0432.CCR-16-2726
Purpose: Human osteosarcoma is a genetically heterogeneous bone malignancy with poor prognosis despite the employment of aggressive chemotherapy regimens. Because druggable driver mutations have not been established, dissecting the interactions betwe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6fc995d21f815df8513d6bb494316e5
https://hdl.handle.net/11368/2967826
https://hdl.handle.net/11368/2967826