Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Takahide Ikeda"'
Autor:
Itaru Kojima, Hiroyuki Morita, Yoshihiko Kitada, Kazuo Kajita, Koichiro Taguchi, Takahide Ikeda, Toshiko Kajita, Tatsuo Ishizuka, Motochika Asano, Masayuki Fuwa
Publikováno v:
The Journal of Endocrinology
Despite extensive investigation, the mechanisms underlying adipogenesis are not fully understood. We previously identified proliferative cells in adipose tissue expressing adipocyte-specific genes, which were named small proliferative adipocytes (SPA
Autor:
Takahide Ikeda, Piyarat Srinontong, Kazunobu Asano, Yoichi Maekawa, Zhiliang Wu, Isao Nagano, Hirokuyi Morita
Publikováno v:
Infection and Immunity. 84:3550-3556
Infectious microorganisms often modify host immunity to escape from immune elimination. Trichinella is a unique nematode of the helminth family, whose members parasitize the muscle cells inside the host without robust eliminative reactions. There are
Autor:
Motochika Asano, Shotaro Kamata, Yoshiko Banno, Toshiko Kajita, Ichiro Mori, Itaru Kojima, Isao Ishii, Tatsuo Ishizuka, Masahiro Yamauchi, Hiroyuki Morita, Mikako Kawashima, Jerold Chun, Takahide Ikeda, Yoshihiko Kitada, Koichiro Taguchi, Kazuo Kajita
Publikováno v:
Endocrinology. 157:1839-1851
Sphingosine 1-phosphate (S1P) is known to regulate insulin resistance in hepatocytes, skeletal muscle cells, and pancreatic β-cells. Among its 5 cognate receptors (S1pr1–S1pr5), S1P seems to counteract insulin signaling and confer insulin resistan
Autor:
Toshiko Kajita, Tsutomu Sasaki, Tatsuo Ishizuka, Ichiro Mori, Itaru Kojima, Kazuo Kajita, Takayuki Hanamoto, Hideyuki Okada, Takashi Sato, Taro Usui, Tadahiro Kitamura, Yoshihiko Kitada, Koichiro Taguchi, Hiroyuki Morita, Takahide Ikeda
Publikováno v:
FEBS Letters. 588:1935-1941
Androgen reduces fat mass, although the underlying mechanisms are unknown. Here, we examined the effect of testosterone on heat production and mitochondrial biogenesis. Testosterone-treated mice exhibited elevated heat production. Treatment with test
Autor:
Yoshihiro Uno, Kei Fujioka, Hideyuki Okada, Tatsuo Ishizuka, Toshiko Kajita, Koichiro Taguchi, Ichiro Mori, Taro Usui, Takayuki Hanamoto, Masahiro Yamauchi, Hiroyuki Morita, Yoshihiko Kitada, Takahide Ikeda, Kazuo Kajita
Publikováno v:
Endocrine Journal. 60:931-939
It has been thought that adipocytes lack proliferative ability and do not revert to precursor cells. However, numerous findings that challenge this notion have also been reported. The idea that adipocytes dedifferentiate to fibroblast-like cells with
Autor:
Takahide Ikeda, Mitsuru Seishima, Hiroyuki Morita, Yoshihiro Uno, Tomoatsu Mune, Chiyo Sugiyama, Jun Takeda, Tatsuo Ishizuka, Masami Matsumoto, Kenji Matsubara, Masao Takemura, Kazuo Kajita
Publikováno v:
Diabetes Research and Clinical Practice. 81:144-149
We investigated the effects of fasting on gene expression and intracellular signals regulating energy metabolism in adipose tissue. Following fasting for 15h or 39h, epididymal fat pads were isolated from Wistar rats. PPARgamma mRNA levels decreased
Effect of nematode Trichinella infection on glucose tolerance and status of macrophage in obese mice
Autor:
Hideyuki, Okada, Takahide, Ikeda, Kazuo, Kajita, Ichiro, Mori, Takayuki, Hanamoto, Kei, Fujioka, Masahiro, Yamauchi, Taro, Usui, Noriko, Takahashi, Yoshihiko, Kitada, Koichiro, Taguchi, Yoshihiro, Uno, Hiroyuki, Morita, Zhiliang, Wu, Isao, Nagano, Yuzo, Takahashi, Takuya, Kudo, Kazuki, Furuya, Takahiro, Yamada, Tatsuo, Ishizuka
Publikováno v:
Endocrine journal. 60(11)
We investigated the effect of Trichinella infection on glucose tolerance and (pro- or anti-inflammatory) macrophage status in adipose tissue. Ob/ob mice and high fat-fed mice (obesity model) and C57/BL mice (control mice) were orally infected with (i
Autor:
Takayuki Hanamoto, Yoshihiko Kitada, Kei Fujioka, Noriko Takahashi, Yoshihiro Uno, Koichiro Taguchi, Masahiro Yamauchi, Taro Usui, Toshiko Kajita, Hiroyuki Morita, Tatsuo Ishizuka, Takahide Ikeda, Hideyuki Okada, Ichiro Mori, Kazuo Kajita
Publikováno v:
Endocrine journal. 60(8)
Obesity consists of hypertrophy and hyperplasia of adipocytes. Although the number of adipocytes is influenced by anatomical location, nutritional environment, hormone and genetic variation, it has been thought to be determined by the proliferation o
Autor:
Tatsuo Ishizuka, Toshiko Kajita, Masahiro Yamauchi, Hiroyuki Morita, Hideyuki Okada, Ichiro Mori, Kazuo Kajita, Kohichiro Taguchi, Kei Fujioka, Takayuki Hanamoto, Noriko Takahashi, Yoshihiko Kitada, Takahide Ikeda, Taro Usui, Yoshihiro Uno
Publikováno v:
Endocrine journal. 59(12)
The possibility that mature adipocytes proliferate has not been fully investigated. In this study, we demonstrate that adipocytes can proliferate. 5-bromo-2'-deoxyuridine (BrdU)-labeled adipocyte like cells, most of which were less than 30 μm in dia
Autor:
Isao Nagano, Yoshihiro Uno, Zhiliang Wu, Masahiro Yamauchi, Hiroyuki Morita, Kei Fujioka, Ichiro Mori, Kazuo Kajita, Takayuki Hanamoto, Yuzo Takahashi, Tatsuo Ishizuka, Hideyuki Okada, Takahide Ikeda
Publikováno v:
American journal of physiology. Endocrinology and metabolism. 302(6)
Several studies have suggested that both testosterone and dehydroepiandrosterone (DHEA) have weight-reducing and antidiabetic effects, especially in rodent studies; however, the precise mechanism of their action remains unclear. Here, we investigated