Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Tadazumi Komiyama"'
Autor:
M. Enamul Kabir, Tadazumi Komiyama, Masahiko Miyamoto, Mahbubur Rahman, Yasuhiro Furuichi, Senthilkumar Krishnaswamy
Publikováno v:
Journal of Molecular Recognition. 24:631-641
Existing antifungal drugs are notable for their inability to act rapidly, as well as their toxicity and limited spectrum. The identification of fungal-specific genes and virulence factors would provide targets for new and influential drugs. The displ
Autor:
Masahiko Miyamoto, Tadazumi Komiyama, Yasuhiro Furuichi, M. Enamul Kabir, Mahbubur Rahman, Senthilkumar Krishnaswamy
Publikováno v:
Journal of Immunological Methods. 366:60-68
Aspergillus fumigatus causes the highly lethal form of invasive aspergillosis (IA). In the present study to develop a novel anti-fungal drug for protection against invasive disease, we identified a single chain fragment variable (scFv) antibody (scFv
Effects of Anthocyanins on Psychological Stress-Induced Oxidative Stress and Neurotransmitter Status
Publikováno v:
Journal of Agricultural and Food Chemistry. 56:7545-7550
There is strong evidence that oxidative stress participates in the etiology of neurodegenerative diseases such as Parkinson's, and Alzheimer's diseases. Moreover, emotional stress effects in the central nervous system play a vital role in homeostasis
Publikováno v:
Free Radical Research. 40:993-1002
Antioxidant activities of 15 purified bilberry anthocyanins together with pelargonidin 3-O-beta-D-glucopyranoside and 4'-O-methyl delphinidin 3-O-beta-D-glucopyranoside (MDp 3-glc), the major metabolite of delphinidin 3-O-beta-D-glucopyranoside (Dp 3
Publikováno v:
Journal of Pharmacological Sciences, Vol 102, Iss 1, Pp 55-63 (2006)
The purpose of the present study was to examine 5-hydroxytryptamine (5-HT)2A-receptor sarpogrelate interactions by site-directed mutagenesis. Based on molecular modeling studies, aspartic acid (Asp)155[3.32] and tryptophan (Trp)151[3.28] in transmemb
Publikováno v:
Pharmacology & Therapeutics. 104:59-81
The serotonin (5-hydroxytryptamine, 5-HT) receptors have conventionally been divided into seven subfamilies, most of which have several subtypes. Among them, 5-HT(2A) receptor is associated with the contraction of vascular smooth muscle, platelet agg
Autor:
M Enamul, Kabir, Senthilkumar, Krishnaswamy, Dakshnamurthy, Selvakumar, Masahiko, Miyamoto, Yasuhiro, Furuichi, Tadazumi, Komiyama
Publikováno v:
Microbiology and immunology. 58(9)
Immunoassay designs rely on the great specificity of antibodies and a suitable marker that facilitates generation of a quantitative signal. Currently, there is no reliable method for measuring the titers of an anti-idiotypic antibody. Our initial att
Autor:
M. Enamul Kabir, Senthilkumar Krishnaswamy, Masahiko Miyamoto, Tadazumi Komiyama, Yasuhiro Furuichi
Publikováno v:
Applied microbiology and biotechnology. 90(2)
Phage-display and competitive panning elution leads to the identification of minimum-sized antigen binders together with conventional antibodies from a mouse cDNA library constructed from HM-1 killer toxin neutralizing monoclonal antibody (nmAb-KT).
Autor:
Tadazumi Komiyama, Senthilkumar Krishnaswamy, M. Enamul Kabir, Yasuhiro Furuichi, Masahiko Miyamoto
Publikováno v:
Protein expression and purification. 72(1)
Single-domain single-chain variable fragment (scFv) antibody is sometimes critical for purification using affinity tagging strategy. We failed in our initial effort to purify a prematurely developed Camelid-like E-tagged short scFv-K2 antibody that c
Autor:
Masahiko Miyamoto, Senthilkumar Krishnaswamy, Yasuhiro Furuichi, Tadazumi Komiyama, M. Enamul Kabir
Publikováno v:
Analytical biochemistry. 395(1)
Phage display and two competitive panning elution conditions were used to isolate Candida-specific single chain fragment variable (scFv) antibodies. An scFv phage library constructed from splenic lymphocytes of mice immunized by idiotypic vaccination