Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Steven C. Rogers"'
Publikováno v:
The journal of nutrition, health & aging. 21:1142-1150
The functional decline that usually accompanies adult aging also encompasses cellular changes including cytoplasmic architecture. In addition to their role in cytoskeletal structure, actin microfilaments have important roles in various cellular proce
p49/STRAP (SRFBP1) is a transcriptional regulator that has been implicated in cardiac aging. p49/STRAP has a SRF binding domain and a BUD22 domain (which modulates cellular growth rate and cell size). We have observed that p49/STRAP alters the intrac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2138348c53d60e64a6facccde75dfc93
https://europepmc.org/articles/PMC4969173/
https://europepmc.org/articles/PMC4969173/
Publikováno v:
BioMed Research International, Vol 2015 (2015)
BioMed Research International
BioMed Research International
The microRNAs and microRNA clusters have been implicated in normal cardiac development and also disease, including cardiac hypertrophy, cardiomyopathy, heart failure, and arrhythmias. Since a microRNA cluster has from two to dozens of microRNAs, the
Publikováno v:
BMC Cell Biology
Background The protein p49/STRAP (SRFBP1) is a transcription cofactor of serum response factor (SRF) which regulates cytoskeletal and muscle-specific genes. Results Two conserved domains were found in the p49/STRAP protein. The SRF-binding domain was