Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Rupinder K. Kanwar"'
Publikováno v:
Drug Discovery Today. 22:1671-1679
In elderly aged related macular degeneration (AMD) is the common eye disease which impairs the vision and most of the time it creates permanent vision loss. Because elderly population constitute the larger percentage among society, visual loss due to
Autor:
Rupinder K. Kanwar, Jagat R. Kanwar, Shailaja Gada Saxena, Arnab Kapat, Colin J. Barrow, Harshali Patil
Publikováno v:
Drug Discovery Today. 22:111-119
Colorectal cancer (CRC) is a major health burden worldwide. The optimal approach to the diagnosis, management, and treatment of CRC involves multidisciplinary and integrated management practices. The field is rapidly changing because of recent advanc
Autor:
Rupinder K. Kanwar, Kislay Roy, Jagat R. Kanwar, S. Stathopoulos, Geoffrey W. Krissansen, Neill W. Haggarty, Alastair K. H. MacGibbon, Angela Rowan, Kay Patricia Palmano
Publikováno v:
Journal of Dairy Science. 99:2488-2501
Inflammatory bowel disease (IBD) is a poorly understood chronic immune disorder for which there is no medical cure. Milk and colostrum are rich sources of bioactives with immunomodulatory properties. Here we compared the therapeutic effects of oral d
Publikováno v:
Nanomedicine. 11:495-511
Aim: To fabricate ultra-small algal chitosan nanoparticles (US CS NPs) for efficient delivery of bovine lactoferrin (bLf) to ocular tissues through topical administration to prevent carbendazim-induced toxicity. Materials & methods: Rat eye model was
Publikováno v:
Biomaterials. 71:84-99
This is the first ever attempt to combine anti-cancer therapeutic effects of emerging anticancer biodrug bovine lactoferrin (bLf), and multimodal imaging efficacy of Fe3O4 nanoparticles (NPs) together, as a saturated Fe3O4-bLf. For cancer stem cell s
Publikováno v:
Mini-Reviews in Medicinal Chemistry. 17
Increasing evidence suggests that stem cells, a small population of cells with unique selfrenewable and tumour regenerative capacity, are aiding tumour re-growth and multidrug resistance. Conventional therapies are highly ineffective at eliminating t
Autor:
Kislay Roy, Rupinder K. Kanwar, Jagat R. Kanwar, Raj Bawa, Krishnakumar Subramanian, Nihal G. Maremanda, Rakesh N. Veedu
Publikováno v:
Current Medicinal Chemistry. 22:2539-2557
Short single-stranded oligonucleotides called aptamers, often termed as chemical antibodies, have been developed as powerful alternatives to traditional antibodies with respect to their obvious advantages like high specificity and affinity, longer sh
Autor:
Muhammad Nasir, Jagat R. Kanwar, Sanjay Garg, Ram Sarup Singh, Shu-Feng Zhou, Alka Sehgal, Kislay Roy, Rakesh Sehgal, Deependra Singh, Yogesh S Patel, Rupinder K. Kanwar, Manju Rawat Singh
Publikováno v:
Molecules
Molecules, Vol 20, Iss 6, Pp 9703-9731 (2015)
Molecules, Vol 20, Iss 6, Pp 9703-9731 (2015)
Lactoferrin (Lf), an iron-binding protein from the transferr in family has been reported to have numerous functions. Even though Lf was first isolated from milk, it is also found in most exocrine secretions and in the secondary granules of neutrophil
Publikováno v:
Nanomedicine. 10:1289-1314
Aim: This study aimed to evaluate the potential antimicrobial efficacy of alginate gel-encapsulated ceramic nanocarriers loaded with iron-saturated bovine lactoferrin (Fe-bLf) nanocarriers/nanocapsules (AEC-CP-Fe-bLf NCs). Materials & methods: The an
Autor:
Sneha Gurudevan, Jayanth Suryanarayanan Shankaranarayanan, Rupinder K. Kanwar, Jagat R. Kanwar
Publikováno v:
Drug Discovery Today. 19:1309-1321
Aptamers have emerged as a novel and powerful class of biomolecules with an immense untapped potential. The ability to synthesise highly specific aptamers against any molecular target make them a vital cog in the design of effective therapeutics for