Zobrazeno 1 - 10
of 103
pro vyhledávání: '"Reinaldo N. Takahashi"'
Publikováno v:
Neuroscience. 497:118-133
Systemic administration of drugs that activate the noradrenergic or glucocorticoid system potentiates aversive memory consolidation and reconsolidation. The opposite happens with the stimulation of endocannabinoid signaling under certain conditions.
Autor:
Fernanda da Rosa, Nuno J. Machado, Pablo Pandolfo, Cristiane Ribeiro de Carvalho, Carolina Melo de Souza, Lisiane O. Porciúncula, Rodrigo A. Cunha, Douglas Teixeira Leffa, Grasielle C. Kincheski, Diogo O. Souza, Samira G. Ferreira, Reinaldo N. Takahashi
Publikováno v:
European Journal of Neuroscience. 49:1673-1683
Attention deficit and hyperactivity disorder (ADHD) is characterized by impaired levels of hyperactivity, impulsivity, and inattention. Adenosine and endocannabinoid systems tightly interact in the modulation of dopamine signaling, involved in the ne
Autor:
Edmar Miyoshi, Reinaldo N. Takahashi, Maria A.B.F. Vital, Palloma de Almeida Soares Hocayen, Claudio Da Cunha, Roberto Andreatini, Etieli Wendler, Luiz Kae Sales Kanazawa, Débora Dalla Vecchia
Publikováno v:
Brain research bulletin. 168
The most common features of Parkinson's disease (PD) are motor impairments, but many patients also present depression and memory impairment. Ketamine, an N-methyl-d-aspartate (NMDA) receptor antagonist, has been shown to be effective in patients with
Publikováno v:
Behavioural Pharmacology. 29:199-210
The factors that trigger the pathophysiology of Parkinson's disease (PD) are unknown. However, it is suggested that environmental factors, such as exposure to pesticides, play an important role, in addition to genetic predisposition and aging. Early
Autor:
Cristina A.J. Stern, Cristiane Ribeiro de Carvalho, Leandro J. Bertoglio, Reinaldo N. Takahashi
Publikováno v:
Neuroscience. 370:62-80
Posttraumatic stress and drug use disorders may stem from aberrant memory formation. As the endocannabinoid (eCB) system has a pivotal role in emotional memory processing and related synaptic plasticity, here we seek to review and discuss accumulatin
Autor:
Giselle F. Passos, Nelson de Mello, Rafael Mariano de Bitencourt, Ana Cristina Guerra de Souza, Rodrigo Medeiros, Fabrício A. Pamplona, Rui Daniel Prediger, Reinaldo N. Takahashi, Maíra A. Bicca, João B. Calixto
Publikováno v:
Behavioural Brain Research. 316:74-81
Previous studies have demonstrated that targeting bradykinin receptors is a promising strategy to counteract the cognitive impairment related with aging and Alzheimer's disease (AD). The hippocampus is critical for cognition, and abnormalities in thi
Autor:
Valentina Cinquina, Cristina Lemos, Attila Köfalvi, Bárbara S. Pinheiro, Rodrigo A. Cunha, Catherine Ledent, Samira G. Ferreira, Reinaldo N. Takahashi, Alán Alpár, Rafael Mariano de Bitencourt, Tibor Harkany, Gert Lubec, Fernando J. Sialana
Publikováno v:
Neurochemistry International. 90:72-84
Corticosteroid and endocannabinoid actions converge on prefrontocortical circuits associated with neuropsychiatric illnesses. Corticosteroids can also modulate forebrain synapses by using endocannabinoid effector systems. Here, we determined whether
Publikováno v:
Pharmacology Biochemistry and Behavior. 136:82-86
The combination of alcohol with an energy drink (ED) is believed to contribute to risky alcohol-drinking behaviors, such as binge drinking. However, the long-term effects on cognition and reward function that are caused by the repeated binge-like ing
Autor:
Rodrigo A. Cunha, Reinaldo N. Takahashi, Joana I. Real, Filipe C. Matheus, Daniel Rial, Rui Daniel Prediger, Cristina Lemos, Leandro J. Bertoglio
Publikováno v:
Molecular Neurobiology. 53:3891-3899
The dorsolateral striatum (DLS) processes motor and non-motor functions and undergoes extensive dopaminergic degeneration in Parkinson's disease (PD). The nigrostriatal dopaminergic degeneration also affects other brain areas including the pre-fronta
Autor:
Cristina A J, Stern, Thiago R, da Silva, Ana M, Raymundi, Camila P, de Souza, Vinicius A, Hiroaki-Sato, Luiza, Kato, Francisco S, Guimarães, Roberto, Andreatini, Reinaldo N, Takahashi, Leandro J, Bertoglio
Publikováno v:
Neuropharmacology. 125
Pharmacological interventions able to modulate a fear memory while it is consolidated could have therapeutic value in tempering those maladaptively overconsolidated. Animal and human studies have shown the intensity of unconditioned stimulus delivere