Zobrazeno 1 - 10
of 136
pro vyhledávání: '"Noel, J."'
Repressor element 1-silencing transcription factor deficiency yields profound hearing loss through K
Autor:
Haiwei, Zhang, Hongchen, Li, Mingshun, Lu, Shengnan, Wang, Xueya, Ma, Fei, Wang, Jiaxi, Liu, Xinyu, Li, Haichao, Yang, Fan, Zhang, Haitao, Shen, Noel J, Buckley, Nikita, Gamper, Ebenezer N, Yamoah, Ping, Lv
Publikováno v:
eLife. 11
Repressor element 1-silencing transcription factor (REST) is a transcriptional repressor that recognizes neuron-restrictive silencer elements in the mammalian genomes in a tissue- and cell-specific manner. The identity of REST target genes and molecu
Publikováno v:
Science, 1972 Jul . 177(4045), 264-267.
Externí odkaz:
https://www.jstor.org/stable/1734549
Autor:
Tariq A. Bhat, Suresh Gopi Kalathil, Yasmin Thanavala, Irfan Rahman, Thivanka Muthumalage, Maciej L. Goniewicz, Noel J. Leigh
Publikováno v:
Nicotine Tob Res
IntroductionEmerging heated tobacco products (HTPs) were designed to reduce exposure to toxicants from cigarette smoke (CS) by avoiding burning tobacco and instead heating tobacco. We studied the effects of short-term inhalation of aerosols emitted f
Autor:
Elizabeth Bloch, Adam E. Snook, Trevor R. Baybutt, Marcos M. Pires, Janessa Wehr, Noel J. Ferraro, Damien Thévenin, Eden L. Sikorski, Mary S. Feigman
Publikováno v:
J Med Chem
A growing class of immunotherapeutic agents work by redirecting components of the immune system to recognize specific markers on the surface of cancer cells and initiate a selective immune response. However, such immunotherapeutic modalities will rem
Autor:
Maile K. Hollinger, Christine M. McIntosh, Maria-Luisa Alegre, Jason B. Williams, Michelle L. Miller, Thomas F. Gajewski, Ying Wang, Noel J. Isaad, James J. Moon, Anita S. Chong
Publikováno v:
Cell Reports. 24:2112-2126
Mechanisms implicated in robust transplantation tolerance at the cellular level can be broadly categorized into those that inhibit alloreactive T cells intrinsically (clonal deletion and dysfunction) or extrinsically through regulation. Here, we inve
Autor:
Satyan Lakshminrusimha, Sara K. Berkelhamer, Maciej L. Goniewicz, Sylvia F. Gugino, Noel J. Leigh, Justin Helman
Publikováno v:
International Journal of Environmental Research and Public Health
International Journal of Environmental Research and Public Health, Vol 16, Iss 19, p 3635 (2019)
International journal of environmental research and public health, vol 16, iss 19
Volume 16
Issue 19
International Journal of Environmental Research and Public Health, Vol 16, Iss 19, p 3635 (2019)
International journal of environmental research and public health, vol 16, iss 19
Volume 16
Issue 19
Background: The developing lung is uniquely susceptible and may be at increased risk of injury with exposure to e-cigarette constituents. We hypothesize that cellular toxicity and airway and vascular responses with exposure to flavored refill solutio
Autor:
Jonathan M. Samet, Hugo Destaillats, Manuela Martins-Green, Georg E. Matt, Suzaynn F. Schick, Lara A. Gundel, Penelope J.E. Quintana, Jian-Hua Mao, Prue Talbot, Todd P. Whitehead, Bo Hang, Noel J. Aquilina, Neal L. Benowitz, Melbourne F. Hovell, Peyton Jacob
Publikováno v:
Jacob, P; Benowitz, NL; Destaillats, H; Gundel, L; Hang, B; Martins-Green, M; et al.(2017). Thirdhand smoke: New evidence, challenges, and future directions. Chemical Research in Toxicology, 30(1), 270-294. doi: 10.1021/acs.chemrestox.6b00343. UC Riverside: Retrieved from: http://www.escholarship.org/uc/item/2nx9f1fj
Chemical research in toxicology, vol 30, iss 1
Chemical research in toxicology, vol 30, iss 1
© 2016 American Chemical Society. Thirdhand smoke (THS) is the contamination that persists after secondhand tobacco smoke has been emitted into air. It refers to the tobacco-related gases and particles that become embedded in materials, such as the
Autor:
Fan, Zhang, Sylvain, Gigout, Yu, Liu, Yiying, Wang, Han, Hao, Noel J, Buckley, Hailin, Zhang, Ian C, Wood, Nikita, Gamper
Publikováno v:
Pain
Supplemental Digital Content is Available in the Text. Transcriptional suppressor, repressor element 1-silencing transcription factor (REST, neuron-restrictive silencing factor), is necessary and sufficient for the development of chronic hyperalgesia
Autor:
Simone P. Niclou, Noel J. Buckley, Maria Angeliki S. Pavlou, Luc Grandbarbe, Alessandro Michelucci
Publikováno v:
Progress in Neurobiology
Astrocytes play a significant role in coordinating neural development and provide critical support for the function of the CNS. They possess important adaptation capacities that range from their transition towards reactive astrocytes to their ability
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5254df8c6b499e40d7978e93a16632e6
https://hdl.handle.net/1956/21678
https://hdl.handle.net/1956/21678
Autor:
Henri Leinonen, Ekaterina Savchenko, Noel J. Buckley, Kari Jalkanen, Lezanne Ooi, Velta Keksa-Goldsteine, Sweelin Chew, Heikki Tanila, Johanna Myllyharju, Petra Oksa, Yajuvinder Singh, Tarja Malm, Katja M. Kanninen, Nadiya Byts, Mikko T. Huuskonen, Deborah J. Guest, Merja Jaronen, Feroze Fazaludeen, Imran Iqbal, Jari Koistinaho
Publikováno v:
Human molecular genetics. 28(19)
The Finnish-variant late infantile neuronal ceroid lipofuscinosis, also known as CLN5 disease, is caused by mutations in the CLN5 gene. Cln5 is strongly expressed in the developing brain and expression continues into adulthood. CLN5, a protein of unk