Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Monika Oberer"'
Autor:
Helgit Eisner, Lina Riegler-Berket, Carlos Francisco Rodriguez Gamez, Theo Sagmeister, Gabriel Chalhoub, Barbara Darnhofer, P J Jazleena, Ruth Birner-Gruenberger, Tea Pavkov-Keller, Guenter Haemmerle, Gabriele Schoiswohl, Monika Oberer
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 21; Pages: 13101
Members of the carboxylesterase 2 (Ces2/CES2) family have been studied intensively with respect to their hydrolytic function on (pro)drugs, whereas their physiological role in lipid and energy metabolism has been realized only within the last few yea
Autor:
Gernot F. Grabner, Nikolaus Guttenberger, Nicole Mayer, Anna K. Migglautsch-Sulzer, Christian Lembacher-Fadum, Nermeen Fawzy, Dominik Bulfon, Peter Hofer, Thomas Züllig, Lennart Hartig, Natalia Kulminskaya, Gabriel Chalhoub, Margarita Schratter, Franz P. W. Radner, Karina Preiss-Landl, Sarah Masser, Achim Lass, Rudolf Zechner, Karl Gruber, Monika Oberer, Rolf Breinbauer, Robert Zimmermann
Publikováno v:
Journal of the American Chemical Society. 144(14)
Chronically elevated circulating fatty acid levels promote lipid accumulation in nonadipose tissues and cause lipotoxicity. Adipose triglyceride lipase (ATGL) critically determines the release of fatty acids from white adipose tissue, and accumulatin
Autor:
Monika Oberer, Natalia Kulminskaya
Publikováno v:
Biochimie. 169:62-68
Carefully regulated lipid homeostastis generates an optimal physiological, non-toxic environment. Imbalances in lipid metabolism lead to obesity and are associated with type-2 diabetes, hepatic steatosis, hypertension and cardiovascular disease. Mamm
Autor:
Guenter Haemmerle, Christoph Dieterich, Tamás Fischer, Sven W. Sauer, Monika Oberer, Jens Tyedmers, Hugo A. Katus, Patrick Most, Lorenz H. Lehmann, Oliver J. Müller, Lisa Wechselberger, Barbara C. Worst, Dominik Siede, Samuel Sossalla, Kumar D Shanmukha, Friederike C. Schreiter, Zegeye H Jebessa, Chang Xu, Johannes Backs, Matthias Dewenter, Giuseppina Federico, Xue-Min Gong, Cedric Moro, Herrmann-Josef Gröne
Publikováno v:
Nature metabolism
Catecholamines stimulate the first step of lipolysis by PKA-dependent release of the lipid droplet-associated protein ABHD5 from perilipin to co-activate the lipase ATGL. Here, we unmask a yet unrecognized proteolytic and cardioprotective function of
Autor:
Rucha Patel, Anna Santoro, Peter Hofer, Dan Tan, Monika Oberer, Andrew T. Nelson, Srihari Konduri, Dionicio Siegel, Rudolf Zechner, Alan Saghatelian, Barbara B. Kahn
Publikováno v:
Nature. 606(7916)
Branched fatty acid (FA) esters of hydroxy FAs (HFAs; FAHFAs) are recently discovered lipids that are conserved from yeast to mammals1,2. A subfamily, palmitic acid esters of hydroxy stearic acids (PAHSAs), are anti-inflammatory and anti-diabetic1,3.
Autor:
Jonathan Rosenberg, Anna Takaćs, Dietmar Riedel, Thomas O. Eichmann, Monika Oberer, Ronald P. Kühnlein, Philip Hehlert, Christoph Heier, Robert Zimmermann, Vinzenz Hofferek, Harald M. Nagy
Publikováno v:
Journal of Lipid Research, Vol 60, Iss 8, Pp 1365-1378 (2019)
J Lipid Res
J Lipid Res
Triglycerides (TGs) are the main energy storage form that accommodates changing organismal energy demands. In Drosophila melanogaster, the TG lipase Brummer is centrally important for body fat mobilization. Its gene brummer (bmm) encodes the ortholog
Autor:
Renate Schreiber, Raymond J. Owens, Monika Oberer, Roland Viertlmayr, Natalia Kulminskaya, Christoph Heier, Mariana Colaço-Gaspar, Rudolf Zechner, Peter Hofer, Robert Zimmermann, Claudia Radler
Publikováno v:
The Journal of Biological Chemistry
Adipose triglyceride lipase (ATGL) plays a key role in intracellular lipolysis, the mobilization of stored triacylglycerol. This work provides an important basis for generating reproducible and detailed data on the hydrolytic and transacylation activ
Autor:
Stephen G. Young, Monika Oberer, Loren G. Fong, André Bensadoun, Michael Ploug, Haibo Jiang, Anne P. Beigneux
Publikováno v:
Trends in endocrinology and metabolism: TEM, vol 27, iss 7
GPIHBP1, a GPI-anchored protein in capillary endothelial cells, is crucial for the lipolytic processing of triglyceride-rich lipoproteins (TRLs). GPIHBP1 shuttles lipoprotein lipase (LPL) to its site of action in the capillary lumen and is essential
Publikováno v:
Curr Protein Pept Sci
Adipose triglyceride lipase (ATGL) is the key-enzyme for the release of fatty acids (FAs) from triacylglycerol (TG) stores during intracellular lipolysis and produces FAs used for energy production. There is growing evidence that the products and int
Autor:
Peter J, Thul, Kirsten, Tschapalda, Petra, Kolkhof, Abdou Rachid, Thiam, Monika, Oberer, Mathias, Beller
Publikováno v:
Journal of cell science. 130(18)
Lipid droplets (LDs) are the principal organelles of lipid storage. They consist of a hydrophobic core of storage lipids, surrounded by a phospholipid monolayer with proteins attached. While some of these proteins are known to be essential for the re