Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Matthew Maurer"'
Autor:
Liang Lei, Joshua U. Klein, Benjamin Amendolara, Zachary Rapp, Benjamin D. Hopkins, Jennifer S. Yu, Barry Fine, Kyrie Pappas, Jeffrey N. Bruce, Maria Luisa Sulis, Matthew Maurer, Cindy Hodakoski, Hanina Hibshoosh, Sarah M. Mense, Meaghan Dendy, Sarah Pegno, Peter Canoll, Hannah E. Goldstein, Ramon Parsons, Nicole Steinbach, Jacquelyn Shaw
Publikováno v:
Science. 341:399-402
PTEN Variations The product of the tumor suppressor gene phosphate and tensin homolog on chromosome ten ( PTEN) is a lipid and protein phosphatase that regulates important cellular processes, including growth, survival, and metabolism (see the Perspe
Autor:
Xiaomei Wang, Mervi Laakso, Y. Rebecca Chin, Carlos Cordon-Cardo, Benjamin D. Hopkins, Hanina Hibshoosh, Susan Koujak, Lao H. Saal, Mary Beth Terry, Jorma Isola, Tao Su, Jiaping Wu, Da In Kim, Jennifer S. Ferris, Yuli Xie, Jean J. Zhao, Jennifer S. Yu, Bhaskar Dutta, Albert Rojtman, Gordon B. Mills, Sofia K. Gruvberger-Saal, Christina R. Barkley, Vundavalli V. Murty, Subhadra V. Nandula, Lorenzo Memeo, Alex Toker, Tulio Matos, Matthew Maurer, Ramon Parsons
Publikováno v:
Cancer Research. 69:6299-6306
Lesions of ERBB2, PTEN, and PIK3CA activate the phosphatidylinositol 3-kinase (PI3K) pathway during cancer development by increasing levels of phosphatidylinositol-3,4,5-triphosphate (PIP3). 3-Phosphoinositide-dependent kinase 1 (PDK1) is the first n
Autor:
Ramon Parsons, Jorma Isola, Johan Vallon-Christersson, Johan Staaf, Lao H. Saal, Tao Su, Karolina Holm, Vundavalli V. Murty, Shivakumar Subramaniyam, Thomas Ludwig, Matthias Szabolcs, Stephen P. Ethier, Matthew Maurer, Göran Jönsson, Kristina Lövgren, Mervi Jumppanen, Camilla Persson, Håkan Olsson, Morten Krogh, Susan Koujak, Hanina Hibshoosh, Lorenzo Memeo, Sofia K. Gruvberger-Saal, Maira M. Pires, Åke Borg
Publikováno v:
Nature Genetics. 40:102-107
Basal-like breast cancer (BBC) is a subtype of breast cancer with poor prognosis1, 2, 3. Inherited mutations of BRCA1, a cancer susceptibility gene involved in double-strand DNA break (DSB) repair, lead to breast cancers that are nearly always of the
Autor:
David Llobet-Navas, Matthew Maurer, Ana Collazo-Lorduy, Jose M. Silva, Veronica Castro, Mariano J. Alvarez, Andrea Califano, Mireia Olivan, Preeti Putcha, Ruth Rodriguez-Barrueco, Carlos Cordon-Cardo, Eva Murga-Penas, Jiyang Yu, Kevin Kalinsky, Laura P. Saucedo-Cuevas, Mireia Castillo-Martin
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
Universidad de Barcelona
HER2-positive (HER2+) breast adenocarcinomas are a heterogeneous group in which hormone receptor (HR) status influences therapeutic decisions and patient outcome. By combining genome-wide RNAi screens with regulatory network analysis, we identified S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a05e71272c1ce0a5c4c38d09e1662cd
http://hdl.handle.net/2445/168553
http://hdl.handle.net/2445/168553
Publikováno v:
Genes & Development. 12:2102-2107
There are two response elements for p53 in the promoter of the gene for the cyclin-dependent kinase inhibitor p21. The binding of p53 to the 5′ site was enhanced by incubation with monoclonal antibody 421, whereas the binding of p53 to the 3′ sit
Autor:
Hugo M. Horlings, Meaghan Dendy, Tao Su, Lao H. Saal, Neal Rosen, Matthew Maurer, Ramon Parsons, Lorenzo Memeo, Qing-Bai She, Mervi Jumppanen, Jorma Isola, Ying Ka Ingar Lau, Sofia K. Gruvberger-Saal, Marc J. van de Vijver, Yilun Chen, Hanina Hibshoosh
Publikováno v:
BMC cancer, 16(1). BioMed Central
BMC Cancer
BMC Cancer
The basal-like breast cancer (BLBC) subtype is characterized by positive staining for basal mammary epithelial cytokeratin markers, lack of hormone receptor and HER2 expression, and poor prognosis with currently no approved molecularly-targeted thera