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Akademický článek
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Publikováno v:
Journal of the Royal Society Interface
Journal of the Royal Society Interface, 2022, 19 (196), ⟨10.1098/rsif.2022.0677⟩
Journal of the Royal Society Interface, 2022, 19 (196), ⟨10.1098/rsif.2022.0677⟩
In the brain, spiking patterns live in a high-dimensional space of neurons and time. Thus, determining the intrinsic structure of this space presents a theoretical and experimental challenge. To address this challenge, we introduce a new framework fo
Autor:
Vanessa Oliveira, John J. Reho, Kirthikaa Balapattabi, McKenzie L. Ritter, Natalia M. Mathieu, Megan A. Opichka, Ko-Ting Lu, Connie C. Grobe, Sebastião D. Silva, Kelsey K. Wackman, Pablo Nakagawa, Jeffrey L. Segar, Curt D. Sigmund, Justin L. Grobe
Publikováno v:
American journal of physiology. Regulatory, integrative and comparative physiology. 323(4)
The renin-angiotensin system (RAS) within the brain is implicated in the control of fluid and electrolyte balance, autonomic functions, blood pressure, and energy expenditure. Mouse models are increasingly used to explore these mechanisms; however, s
Autor:
Vitale, Ilio, Pietrocola, Federico, Guilbaud, Emma, Aaronson, Stuart A, Abrams, John M, Adam, Dieter, Agostini, Massimiliano, Agostinis, Patrizia, Alnemri, Emad S, Altucci, Lucia, Amelio, Ivano, Andrews, David W, Aqeilan, Rami I, Arama, Eli, Baehrecke, Eric H, Balachandran, Siddharth, Bano, Daniele, Barlev, Nickolai A, Bartek, Jiri, Bazan, Nicolas G, Becker, Christoph, Bernassola, Francesca, Bertrand, Mathieu J M, Bianchi, Marco E, Blagosklonny, Mikhail V, Blander, J Magarian, Blandino, Giovanni, Blomgren, Klas, Borner, Christoph, Bortner, Carl D, Bove, Pierluigi, Boya, Patricia, Brenner, Catherine, Broz, Petr, Brunner, Thomas, Damgaard, Rune Busk, Calin, George A, Campanella, Michelangelo, Candi, Eleonora, Carbone, Michele, Carmona-Gutierrez, Didac, Cecconi, Francesco, Chan, Francis K-M, Chen, Guo-Qiang, Chen, Quan, Chen, Youhai H, Cheng, Emily H, Chipuk, Jerry E, Cidlowski, John A, Ciechanover, Aaron, Ciliberto, Gennaro, Conrad, Marcus, Cubillos-Ruiz, Juan R, Czabotar, Peter E, D'Angiolella, Vincenzo, Daugaard, Mads, Dawson, Ted M, Dawson, Valina L, De Maria, Ruggero, De Strooper, Bart, Debatin, Klaus-Michael, Deberardinis, Ralph J, Degterev, Alexei, Del Sal, Giannino, Deshmukh, Mohanish, Di Virgilio, Francesco, Diederich, Marc, Dixon, Scott J, Dynlacht, Brian D, El-Deiry, Wafik S, Elrod, John W, Engeland, Kurt, Fimia, Gian Maria, Galassi, Claudia, Ganini, Carlo, Garcia-Saez, Ana J, Garg, Abhishek D, Garrido, Carmen, Gavathiotis, Evripidis, Gerlic, Motti, Ghosh, Sourav, Green, Douglas R, Greene, Lloyd A, Gronemeyer, Hinrich, Häcker, Georg, Hajnóczky, György, Hardwick, J Marie, Haupt, Ygal, He, Sudan, Heery, David M, Hengartner, Michael O, Hetz, Claudio, Hildeman, David A, Ichijo, Hidenori, Inoue, Satoshi, Jäättelä, Marja, Janic, Ana, Joseph, Bertrand, Jost, Philipp J, Kanneganti, Thirumala-Devi, Karin, Michael, Kashkar, Hamid, Kaufmann, Thomas, Kelly, Gemma L, Kepp, Oliver, Kimchi, Adi, Kitsis, Richard N, Klionsky, Daniel J, Kluck, Ruth, Krysko, Dmitri V, Kulms, Dagmar, Kumar, Sharad, Lavandero, Sergio, Lavrik, Inna N, Lemasters, John J, Liccardi, Gianmaria, Linkermann, Andreas, Lipton, Stuart A, Lockshin, Richard A, López-Otín, Carlos, Luedde, Tom, MacFarlane, Marion, Madeo, Frank, Malorni, Walter, Manic, Gwenola, Mantovani, Roberto, Marchi, Saverio, Marine, Jean-Christophe, Martin, Seamus J, Martinou, Jean-Claude, Mastroberardino, Pier G, Medema, Jan Paul, Mehlen, Patrick, Meier, Pascal, Melino, Gerry, Melino, Sonia, Miao, Edward A, Moll, Ute M, Muñoz-Pinedo, Cristina, Murphy, Daniel J, Niklison-Chirou, Maria Victoria, Novelli, Flavia, Núñez, Gabriel, Oberst, Andrew, Ofengeim, Dimitry, Opferman, Joseph T, Oren, Moshe, Pagano, Michele, Panaretakis, Theocharis, Pasparakis, Manolis, Penninger, Josef M, Pentimalli, Francesca, Pereira, David M, Pervaiz, Shazib, Peter, Marcus E, Pinton, Paolo, Porta, Giovanni, Prehn, Jochen H M, Puthalakath, Hamsa, Rabinovich, Gabriel A, Rajalingam, Krishnaraj, Ravichandran, Kodi S, Rehm, Markus, Ricci, Jean-Ehrland, Rizzuto, Rosario, Robinson, Nirmal, Rodrigues, Cecilia M P, Rotblat, Barak, Rothlin, Carla V, Rubinsztein, David C, Rudel, Thomas, Rufini, Alessandro, Ryan, Kevin M, Sarosiek, Kristopher A, Sawa, Akira, Sayan, Emre, Schroder, Kate, Scorrano, Luca, Sesti, Federico, Shao, Feng, Shi, Yufang, Sica, Giuseppe S, Silke, John, Simon, Hans-Uwe, Sistigu, Antonella, Stephanou, Anastasis, Stockwell, Brent R, Strapazzon, Flavie, Strasser, Andreas, Sun, Liming, Sun, Erwei, Sun, Qiang, Szabadkai, Gyorgy, Tait, Stephen W G, Tang, Daolin, Tavernarakis, Nektarios, Troy, Carol M, Turk, Boris, Urbano, Nicoletta, Vandenabeele, Peter, Vanden Berghe, Tom, Vander Heiden, Matthew G, Vanderluit, Jacqueline L, Verkhratsky, Alexei, Villunger, Andreas, von Karstedt, Silvia, Voss, Anne K, Vousden, Karen H, Vucic, Domagoj, Vuri, Daniela, Wagner, Erwin F, Walczak, Henning, Wallach, David, Wang, Ruoning, Wang, Ying, Weber, Achim, Wood, Will, Yamazaki, Takahiro, Yang, Huang-Tian, Zakeri, Zahra, Zawacka-Pankau, Joanna E, Zhang, Lin, Zhang, Haibing, Zhivotovsky, Boris, Zhou, Wenzhao, Piacentini, Mauro, Kroemer, Guido, Galluzzi, Lorenzo
Publikováno v:
Vitale, I, Pietrocola, F, Guilbaud, E, Aaronson, S A, Abrams, J M, Adam, D, Agostini, M, Agostinis, P, Alnemri, E S, Altucci, L, Amelio, I, Andrews, D W, Aqeilan, R I, Arama, E, Baehrecke, E H, Balachandran, S, Bano, D, Barlev, N A, Bartek, J, Bazan, N G, Becker, C, Bernassola, F, Bertrand, M J M, Bianchi, M E, Blagosklonny, M V, Blander, J M, Blandino, G, Blomgren, K, Borner, C, Bortner, C D, Bove, P, Boya, P, Brenner, C, Broz, P, Brunner, T, Damgaard, R B, Calin, G A, Campanella, M, Candi, E, Carbone, M, Carmona-Gutierrez, D, Cecconi, F, Chan, F K M, Chen, G Q, Chen, Q, Chen, Y H, Cheng, E H, Chipuk, J E, Cidlowski, J A, Ciechanover, A, Ciliberto, G, Conrad, M, Cubillos-Ruiz, J R, Czabotar, P E, D’Angiolella, V, Daugaard, M, Dawson, T M, Dawson, V L, De Maria, R, De Strooper, B, Debatin, K M, Deberardinis, R J, Degterev, A, Del Sal, G, Deshmukh, M, Di Virgilio, F, Diederich, M, Dixon, S J, Dynlacht, B D, El-Deiry, W S, Elrod, J W, Engeland, K, Fimia, G M, Galassi, C, Ganini, C, Garcia-Saez, A J, Garg, A D, Garrido, C, Gavathiotis, E, Gerlic, M, Ghosh, S, Green, D R, Greene, L A, Gronemeyer, H, Häcker, G, Hajnóczky, G, Hardwick, J M, Haupt, Y, He, S, Heery, D M, Hengartner, M O, Hetz, C, Hildeman, D A, Ichijo, H, Inoue, S, Jäättelä, M, Janic, A, Joseph, B, Jost, P J, Kanneganti, T D, Karin, M, Kashkar, H, Kaufmann, T, Kelly, G L, Kepp, O, Kimchi, A, Kitsis, R N, Klionsky, D J, Kluck, R, Krysko, D V, Kulms, D, Kumar, S, Lavandero, S, Lavrik, I N, Lemasters, J J, Liccardi, G, Linkermann, A, Lipton, S A, Lockshin, R A, López-Otín, C, Luedde, T, MacFarlane, M, Madeo, F, Malorni, W, Manic, G, Mantovani, R, Marchi, S, Marine, J C, Martin, S J, Martinou, J C, Mastroberardino, P G, Medema, J P, Mehlen, P, Meier, P, Melino, G, Melino, S, Miao, E A, Moll, U M, Muñoz-Pinedo, C, Murphy, D J, Niklison-Chirou, M V, Novelli, F, Núñez, G, Oberst, A, Ofengeim, D, Opferman, J T, Oren, M, Pagano, M, Panaretakis, T, Pasparakis, M, Penninger, J M, Pentimalli, F, Pereira, D M, Pervaiz, S, Peter, M E, Pinton, P, Porta, G, Prehn, J H M, Puthalakath, H, Rabinovich, G A, Rajalingam, K, Ravichandran, K S, Rehm, M, Ricci, J E, Rizzuto, R, Robinson, N, Rodrigues, C M P, Rotblat, B, Rothlin, C V, Rubinsztein, D C, Rudel, T, Rufini, A, Ryan, K M, Sarosiek, K A, Sawa, A, Sayan, E, Schroder, K, Scorrano, L, Sesti, F, Shao, F, Shi, Y, Sica, G S, Silke, J, Simon, H U, Sistigu, A, Stephanou, A, Stockwell, B R, Strapazzon, F, Strasser, A, Sun, L, Sun, E, Sun, Q, Szabadkai, G, Tait, S W G, Tang, D, Tavernarakis, N, Troy, C M, Turk, B, Urbano, N, Vandenabeele, P, Vanden Berghe, T, Vander Heiden, M G, Vanderluit, J L, Verkhratsky, A, Villunger, A, von Karstedt, S, Voss, A K, Vousden, K H, Vucic, D, Vuri, D, Wagner, E F, Walczak, H, Wallach, D, Wang, R, Wang, Y, Weber, A, Wood, W, Yamazaki, T, Yang, H T, Zakeri, Z, Zawacka-Pankau, J E, Zhang, L, Zhang, H, Zhivotovsky, B, Zhou, W, Piacentini, M, Kroemer, G & Galluzzi, L 2023, ' Apoptotic cell death in disease—Current understanding of the NCCD 2023 ', Cell Death and Differentiation, vol. 30, no. 5, pp. 1097-1154 . https://doi.org/10.1038/s41418-023-01153-w
Cell death and differentiation 30(5), 1097-1154 (2023). doi:10.1038/s41418-023-01153-w
Cell death and differentiation 30(5), 1097-1154 (2023). doi:10.1038/s41418-023-01153-w
58 p.-5 fig.-7 box.
Apoptosis is a form of regulated cell death (RCD) that involves proteases of the caspase family. Pharmacological and genetic strategies that experimentally inhibit or delay apoptosis in mammalian systems have elucidated the k
Apoptosis is a form of regulated cell death (RCD) that involves proteases of the caspase family. Pharmacological and genetic strategies that experimentally inhibit or delay apoptosis in mammalian systems have elucidated the k
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab2b742266215ffe65e96dc332753aba
https://orbit.dtu.dk/en/publications/0f60f683-cf55-4ff1-9d52-631620c6ad87
https://orbit.dtu.dk/en/publications/0f60f683-cf55-4ff1-9d52-631620c6ad87
Autor:
Olivier Reynard, Claudia Gonzalez, Claire Dumont, Mathieu Iampietro, Marion Ferren, Sandrine Le Guellec, Lajoie Laurie, Cyrille Mathieu, Gabrielle Carpentier, Georges Roseau, Francesca T. Bovier, Yun Zhu, Deborah Le Pennec, Jérome Montharu, Amin Addetia, Alexander L. Greninger, Christopher A. Alabi, Elise Brisebard, Anne Moscona, Laurent Vecellio, Matteo Porotto, Branka Horvat
Publikováno v:
Nature Communications
Nature Communications, 2022, 13 (1), pp.6439. ⟨10.1038/s41467-022-33832-6⟩
Nature Communications, 2022, 13 (1), pp.6439. ⟨10.1038/s41467-022-33832-6⟩
Measles is the most contagious airborne viral infection and the leading cause of child death among vaccine-preventable diseases. We show here that aerosolized lipopeptide fusion inhibitors, derived from heptad-repeat regions of the measles virus (MeV
Akademický článek
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Publikováno v:
Biochemical and Biophysical Research Communications. 636:84-88
Pregnenolone (P5) is a steroid that functions in the brain and in zebrafish embryogenesis. It is synthesized from cholesterol via the enzymatic activity of P450scc, encoded by CYP11A1. P5 exerts its function by activating CLIP1, which in turn promote
Autor:
Agustinus, Albert, Al-Rawi, Duaa, Dameracharla, Bhargavi, Raviram, Ramya, Jones, Bailey, Stransky, Stephanie, Scipioni, Lorenzo, Luebeck, Jens, Di Bona, Melody, Norkunaite, Danguole, Myers, Robert, Duran, Mercedes, Choi, Seongmin, Weigelt, Britta, Yomtoubian, Shira, McPherson, Andrew, Toufektchan, Eléonore, Keuper, Kristina, Mischel, Paul, Mittal, Vivek, Shah, Sohrab, Maciejowski, John, Storchova, Zuzana, Ly, Peter, Landau, Dan, Bakhoum, Mathieu, Koche, Richard, Sidoli, Simone, Bafna, Vineet, David, Yael, Bakhoum, Samuel, Gratton, Enrico
Publikováno v:
Nature, vol 619, iss 7968
Chromosomal instability (CIN) and epigenetic alterations are characteristics of advanced and metastatic cancers1-4, but whether they are mechanistically linked is unknown. Here we show that missegregation of mitotic chromosomes, their sequestration i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::3e99b432e6948184a6272a85e54241d8
https://escholarship.org/uc/item/25b0n7j7
https://escholarship.org/uc/item/25b0n7j7
Autor:
Bart Vanderborght, Kevin De Muynck, Eva Gijbels, Sander Lefere, Charlotte L. Scott, Martin Guilliams, Alain Beschin, Mathieu Vinken, Xavier Verhelst, Anja Geerts, Hans Van Vlierberghe, Lindsey Devisscher
Due to a combination of rapid disease progression and the lack of curative treatment options, hepatocellular carcinoma (HCC) is one of the deadliest cancers worldwide. Infiltrated, monocyte-derived, tumor-associated macrophages are known to play a ro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f78223dfe22a1be1194ef1c39ea57b4
https://doi.org/10.1002/ijc.34505
https://doi.org/10.1002/ijc.34505