Zobrazeno 1 - 10
of 51
pro vyhledávání: '"M. Hansson"'
Autor:
Lars Muhl, Liqun He, Ying Sun, Maarja Andaloussi Mäe, Riikka Pietilä, Jianping Liu, Guillem Genové, Lei Zhang, Yuan Xie, Stefanos Leptidis, Giuseppe Mocci, Simon Stritt, Ahmed Osman, Andrey Anisimov, Karthik Amudhala Hemanthakumar, Markus Räsänen, Emil M. Hansson, Johan Björkegren, Michael Vanlandewijck, Klas Blomgren, Taija Mäkinen, Xiao-Rong Peng, Yizhou Hu, Patrik Ernfors, Thomas D. Arnold, Kari Alitalo, Urban Lendahl, Christer Betsholtz
Humanized mouse models and mouse-adapted SARS-CoV-2 virus are increasingly used to study COVID-19 pathogenesis, so it is impor-tant to learn where the SARS-CoV-2 receptor ACE2 is expressed. Here we mapped ACE2 expression during mouse postnatal develo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48773163c4f779200f287930f67ceac5
http://hdl.handle.net/10138/345993
http://hdl.handle.net/10138/345993
Autor:
Tim R. Eijgenraam, Nienke M. Stege, Vivian Oliveira Nunes Teixeira, Remco de Brouwer, Elisabeth M. Schouten, Niels Grote Beverborg, Liu Sun, Daniela Später, Ralph Knöll, Kenny M. Hansson, Carl Amilon, David Janzén, Steve T. Yeh, Adam E. Mullick, Peter van der Meer, Rudolf A. de Boer, Herman H. W. Silljé
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 5; Pages: 2427
International Journal of Molecular Sciences, 23(5):2427. MDPI AG
International Journal of Molecular Sciences, 23(5):2427. MDPI AG
Inherited cardiomyopathy caused by the p.(Arg14del) pathogenic variant of the phospholamban (PLN) gene is characterized by intracardiomyocyte PLN aggregation and can lead to severe dilated cardiomyopathy. We recently reported that pre-emptive depleti
Autor:
Anna Lundahl, Kenneth R. Chien, Peter Gennemark, Shayn M. Peirce, Anthony C. Bruce, S. Michaela Rikard, Joachim Almquist, Maria Wågberg, Kenny M. Hansson, Regina Fritsche-Danielson
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 9, Iss 7, Pp 384-394 (2020)
CPT: Pharmacometrics & Systems Pharmacology
CPT: Pharmacometrics & Systems Pharmacology
Intradermal delivery of AZD8601, an mRNA designed to produce vascular endothelial growth factor A (VEGF-A), has previously been shown to accelerate cutaneous wound healing in a murine diabetic model. Here, we develop population pharmacokinetic and ph
Autor:
Lars Muhl, Giuseppe Mocci, Riikka Pietilä, Jianping Liu, Liqun He, Guillem Genové, Stefanos Leptidis, Sonja Gustafsson, Byambajav Buyandelger, Elisabeth Raschperger, Emil M. Hansson, Johan L.M. Björkegren, Michael Vanlandewijck, Urban Lendahl, Christer Betsholtz
Publikováno v:
Developmental Cell. 57:2426-2443.e6
Smooth muscle cells (SMCs) execute important physiological functions in numerous vital organ systems, including the vascular, gastrointestinal, respiratory, and urogenital tracts. SMC differ morphologically and functionally at these different anatomi
Autor:
Jason S. L. Yu, Alleyn T. Plowright, Cindy Lim, Lauren Drowley, Giorgia Palano, Kosuke Yusa, Mohammad Bohlooly-Y, Qing-Dong Wang, Aldo Moggio, Emil M. Hansson, Barry Rosen
Publikováno v:
Stem Cells (Dayton, Ohio)
Direct in vivo reprogramming of cardiac fibroblasts into myocytes is an attractive therapeutic intervention in resolving myogenic deterioration. Current transgene-dependent approaches can restore cardiac function, but dependence on retroviral deliver
Autor:
Ying Sun, Stefanos Leptidis, Elisabeth Raschperger, Giuseppe Mocci, Emil M. Hansson, Christer Betsholtz, Åsa Segerstolpe, Michael Vanlandewijck, Lars Muhl, Urban Lendahl, Indira V. Chivukula, Johan Björkegren, Liqun He, Xiao-Rong Peng, Jianping Liu, Byambajav Buyandelger, Sonja Gustafsson, Guillem Genové
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
Nature Communications
Nature Communications
Many important cell types in adult vertebrates have a mesenchymal origin, including fibroblasts and vascular mural cells. Although their biological importance is undisputed, the level of mesenchymal cell heterogeneity within and between organs, while
Autor:
Karin J Johansson, Susanne Pehrsson, Ann Lövgren, Anna Lindblom, Kenny M. Hansson, Karin Nelander
Publikováno v:
Blood coagulationfibrinolysis : an international journal in haemostasis and thrombosis. 30(4)
Uncontrolled bleeding due to trauma and coagulopathy is an area with high unmet medical need and high mortality rate. Treatment recommendations focus on transfusion of blood components while optimal therapy to improve coagulation remains to be establ
Publikováno v:
Haemophilia. 22:453-461
BACKGROUND Haemophilia A and B are treated with FVIII and FIX replacement therapy. Treatment may be complicated by inhibitory antibodies that require bypass therapy such as FEIBA(®) in which prothrombin (FII) is suggested to be the main active compo
Autor:
Cassandra L. Fraser, Bo Ning, Chenchu Zhang, Michaela Rikard, Shayn M. Peirce, Scott A. Seaman, Naidi Sun, Regina Fritsche-Danielson, Maria Wågberg, Kenneth R. Chien, Kenny M. Hansson, Anthony C. Bruce, Christopher A. DeRosa, Song Hu, Leif Carlsson, Johannes Wikström, Anna Lundahl, Mikko Hölttä
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Scientific Reports
Scientific Reports
Capable of mediating efficient transfection and protein production without eliciting innate immune responses, chemically modified mRNA holds great potential to produce paracrine factors at a physiologically beneficial level, in a spatiotemporally con
Autor:
Yue, Zhang, Kenny M, Hansson, Tao, Liu, Kerstin, Magnell, Yufeng, Huang, Noel G, Carlson, Bellamkonda K, Kishore
Publikováno v:
Acta physiologica (Oxford, England). 225(2)
Therapeutic use of lithium in bipolar disorder is limited by the development of nephrogenic diabetes insipidus (NDI). We reported that pharmacological blockade of P2YAt both time points, lithium-induced polyuria and decrease in aquaporin-2 (AQP2) pro