Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Liang Cheng Chen"'
Autor:
Chih-Hsien Chang, Wei-Lin Lo, Su-Jung Chen, Liang-Cheng Chen, Yuan-Ruei Huang, Ming-Wei Chen, Ming-Hsin Li, Shih-Wei Lo
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 5459, p 5459 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 11
International Journal of Molecular Sciences
Volume 22
Issue 11
The Arg–Gly–Asp (RGD) peptide shows a high affinity for αvβ3 integrin, which is overexpressed in new tumor blood vessels and many types of tumor cells. The radiolabeled RGD peptide has been studied for cancer imaging and radionuclide therapy. W
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 3868, p 3868 (2021)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
Nanoliposomes are one of the leading potential nano drug delivery systems capable of targeting chemotherapeutics to tumor sites because of their passive nano-targeting capability through the enhanced permeability and retention (EPR) effect for cancer
Autor:
Wei-Chuan Hsu, Tsung-Tse Wu, Kai-Hung Cheng, Chih-Hsien Chang, Ya-Jen Chang, Liang-Cheng Chen, Wan-I Kuo
Publikováno v:
Anticancer Research. 39:183-190
Background/aim Cetuximab has exhibited high EGFR-targeting specificity and clinical promise in previous studies. In this study, we formulated unit dose kits for preparation of high specific activity 188Re-cetuximab for imaging and treatment of EGFR-p
Autor:
Lo Sheng-Nan, Lee Shih-Ying, Ruei-Min Lu, I-Ju Liu, Chen-Hsien Liang, Chih-Hsien Chang, Liang-Cheng Chen, Wei-Lin Lo, Han-Chung Wu, Ming-Wei Chen
Publikováno v:
Applied Radiation and Isotopes. 161:109162
The objective of this study was to evaluate radiolabeled DOTA-SP90 as a radiotracer for breast cancer. The in vitro competition assay showed that radiolabeled DOTA-SP90 had significant binding affinity to BT-483 cancer cells. Biodistribution, nanoSPE
Autor:
Liang-Cheng, Chen, Wan-Chi, Lee, Chung-Li, Ho, Ya-Jen, Chang, Su-Jung, Chen, Chih-Hsien, Chang
Publikováno v:
In vivo (Athens, Greece). 32(3)
Background/Aim: The biodistribution, pharmaco-kinetics and therapeutic evaluation of 188Re-human serum albumin microspheres (188Re-HSAM) by labeling with 188Re(I)-tricarbonyl ion (188Re(OH2)3(CO)3)+) were investigated in a GP7TB orthotopic hepatoma r
Autor:
Wan-Chi Lee, Chih-Hsien Chang, Chia-Yu Yu, Te-Wei Lee, Liang-Cheng Chen, Cheng-Hui Chuang, Chien-Hong Lin, Su-Jung Chen, Chung-Li Ho, Hsiao-Chiang Ni
Publikováno v:
Applied Radiation and Isotopes. 99:117-121
Objective The present study relates to a method for preparing 188Re-labeled human serum albumin microspheres (HSAM) by 188Re(I)-tricarbonyl ion(188Re(OH2)3(CO)3)+). This radioactive particle can be subjected to radioembolization for liver tumor. Meth
Autor:
Liang-Cheng, Chen, Ya-Jen, Chang, Su-Jung, Chen, Wan-Chi, Lee, Chih-Hsien, Chang, Te-Wei, Lee, Jui-Hung, Shien
Publikováno v:
International journal of radiation biology. 93(5)
Liver cancer is the second most common cause of death worldwide. This study was to investigate the SPECT/CT, ultrasound, biodistribution and therapeutic evaluation ofHSAM was labeled withThe biodistribution and nanoSPECT/CT imaging showed thatThese r
Autor:
Fu Du Chen, Yi-Yu Lin, Hsin Ell Wang, Ya-Jen Chang, Michael G. Stabin, Wuu-Jyh Lin, Liang-Cheng Chen, Te-Wei Lee, Cheng Allen Chang, Chih-Hsien Chang, Yun Long Tseng, Gann Ting, Ming-Hsien Lin, Jia-Je Li
Publikováno v:
Cancer Biotherapy and Radiopharmaceuticals. 26:373-380
PEGylated liposomes are important drug carriers for nanomedicine cancer therapy. PEGylated liposomes can encapsulate radio- and chemo-drugs and passively target tumor sites via enhanced permeability and retention effect. This study estimated the phar
Autor:
Tung-Chuan Chiang, Chih-Hsien Chang, Ya-Jen Chang, Liang-Cheng Chen, Hsiao-Lin Chen, Chin-Wei Hsu, Chi-Mou Liu, Chia-Yu Yu, Tsui-Jung Chang, Chung-Li Ho, Te-Wei Lee
Publikováno v:
Journal of Applied Toxicology. 30:680-687
Liposomes can selectively target cancer sites and carry payloads, thereby improving diagnostic and therapeutic effectiveness and reducing toxicity. To evaluate therapeutic strategies, it is essential to use animal models reflecting important safety a
Autor:
Chia-Yu Yu, Min-Hua Chen, Chih-Hsien Chang, Ya-Jen Chang, Liang-Cheng Chen, Tsui-Jung Chang, Gann Ting, Te-Wei Lee
Publikováno v:
Nuclear Medicine and Biology. 37:95-104
Nanocarriers can selectively target cancer sites and carry payloads, thereby improving diagnostic and therapeutic effectiveness and reducing toxicity. The objective of this study was to investigate the therapeutic efficacy of a new co-delivery radioc