Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Larisa V, Gubareva"'
Autor:
Mira C, Patel, Daniel, Flanigan, Chenchen, Feng, Anton, Chesnokov, Ha T, Nguyen, Anwar Abd, Elal, John, Steel, Rebecca J, Kondor, David E, Wentworth, Larisa V, Gubareva, Vasiliy P, Mishin
Publikováno v:
Antiviral Research. 208:105457
Year-round virological characterization of circulating epidemic influenza viruses is conducted worldwide to detect the emergence of viruses that may escape pre-existing immunity or acquire resistance to antivirals. High throughput phenotypic assays a
Autor:
Michael G. Ison, Frederick G. Hayden, Emi Takashita, Elena A. Govorkova, Jennifer L. McKimm-Breschkin, Alan J. Hay, Larisa V. Gubareva
Publikováno v:
Antiviral Res
It is more than 20 years since the neuraminidase inhibitors, oseltamivir and zanamivir were approved for the treatment and prevention of influenza. Guidelines for global surveillance and methods for evaluating resistance were established initially by
Autor:
Jen Laplante, Bo Shu, Francine Cigel, Joyce Jones, Juan A. De La Cruz, Sandra Newbury, Christopher T. Lee, Atanaska Marinova-Petkova, Yunho Jang, Jessica A. Belser, Mia Kim Torchetti, LaShondra Berman, Erin Hodges, David E. Wentworth, Stephen Lindstrom, Joseph S. Bresee, Natosha Zanders, Kirsten St. George, Thomas J. Stark, John R. Barnes, Fiona Havers, Larisa V. Gubareva, Dakai Liu, Patrick Yang, Demetre Daskalakis, Marisela R. Rodriguez, Hua Yang, Sharmi Thor, Susan C. Trock, Alicia M. Fry, Kathy Toohey-Kurth, C. Todd Davis, Paul J. Carney, James Stevens, Brian Lynch
Publikováno v:
Emerging Infectious Diseases, Vol 23, Iss 12, Pp 2046-2049 (2017)
Emerging Infectious Diseases
Emerging Infectious Diseases
An outbreak of influenza A(H7N2) virus in cats in a shelter in New York, NY, USA, resulted in zoonotic transmission. Virus isolated from the infected human was closely related to virus isolated from a cat; both were related to low pathogenicity avian
Autor:
Le Thi Thanh, Le Quynh Mai, Amanda Balish, James C. Kile, Ngo Thu Huong, Adrian Creanga, Vuong Duc Cuong, Nguyen Co Thach, Nguyen Hoang Dang, Larisa V. Gubareva, Alexander Klimov, Mai Thuy Duong, Bryan K. Kapella, Hoang Vu Mai Phuong, C. Todd Davis, Nguyen Tran Hien, Ha T. Nguyen, Yunho Jang, Pham Thi Hien, Nguyen Le Khanh Hang, Nguyen Dang Tho, Nguyen Thanh Tung, Do Ngoc Hoa
Publikováno v:
The Journal of Infectious Diseases. 216:S529-S538
Mutation and reassortment of highly pathogenic avian influenza A(H5N1) viruses at the animal-human interface remain a major concern for emergence of viruses with pandemic potential. To understand the relationship of H5N1 viruses circulating in poultr
Autor:
Todd Davis, Natosha Zanders, David E. Wentworth, Joyce Jones, Larisa V. Gubareva, Juan A. De La Cruz, Anton Chesnokov, Mira C. Patel, Ha T. Nguyen, Vasiliy P. Mishin
Publikováno v:
Antiviral Research. 188:105035
Pimodivir exerts an antiviral effect on the early stages of influenza A virus replication by inhibiting the cap-binding function of polymerase basic protein 2 (PB2). In this study, we used a combination of sequence analysis and phenotypic methods to
Autor:
Larisa V. Gubareva, Juan A. De La Cruz, Anton Chesnokov, Mira C. Patel, Ha T. Nguyen, Lori Lollis, Vasiliy P. Mishin, David E. Wentworth, Vivien G. Dugan
Publikováno v:
J Infect Dis
Susceptibility of influenza A viruses to baloxavir can be affected by changes at amino acid residue 38 in the polymerase acidic (PA) protein. Information on replicative fitness of PA-I38-substituted viruses remains sparse. We demonstrated that substi
Autor:
Vasiliy P, Mishin, Mira C, Patel, Anton, Chesnokov, Juan, De La Cruz, Ha T, Nguyen, Lori, Lollis, Erin, Hodges, Yunho, Jang, John, Barnes, Timothy, Uyeki, Charles T, Davis, David E, Wentworth, Larisa V, Gubareva
Publikováno v:
Emerging Infectious Diseases
Baloxavir showed broad-spectrum in vitro replication inhibition of 4 types of influenza viruses (90% effective concentration range 1.2–98.3 nmol/L); susceptibility pattern was influenza A ˃ B ˃ C ˃ D. This drug also inhibited influenza A viruses
Autor:
Erin Hodges, John R. Barnes, Larisa V. Gubareva, Vasiliy P. Mishin, Anton Chesnokov, Rebecca Garten, Jackie Katz, Ha T. Nguyen, Brian R Mann, Patricia A. Jorquera, Juan A. De La Cruz, Xiyan Xu, David E. Wentworth
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-16 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-16 (2019)
Influenza A(H3N2) viruses evade human immunity primarily by acquiring antigenic changes in the haemagglutinin (HA). HA receptor-binding features of contemporary A(H3N2) viruses hinder traditional antigenic characterization using haemagglutination inh
Autor:
Malania M. Wilson, John Barnes, Larisa V. Gubareva, Juan A. De La Cruz, Rebecca Kondor, David E. Wentworth, Anton Chesnokov, Mira C. Patel, Vasiliy P. Mishin, Ha T. Nguyen
Publikováno v:
Antiviral Research
Baloxavir, a new antiviral drug targeting cap-dependent endonuclease activity of polymerase acidic (PA) protein of influenza viruses, is now approved in multiple countries. Several substitutions at isoleucine 38 in PA protein (e.g., PA-I38T) have bee
Autor:
Ho-Sheng Wu, Daisuke Tamura, Katrina Sleeman, Larisa V. Gubareva, Juan A. De La Cruz, Alicia M. Fry, Feng-Yee Chang, Julie Villanueva, Henju Marjuki, Nancy J. Cox, Anton Chesnokov, Ha T. Nguyen, Ming-Tsan Liu, Charles T. Davis, Vasiliy P. Mishin, Joyce Jones
Publikováno v:
Journal of Infectious Diseases. 211:249-257
Background Patients contracting influenza A(H7N9) infection often developed severe disease causing respiratory failure. Neuraminidase (NA) inhibitors (NAIs) are the primary option for treatment, but information on drug-resistance markers for influenz