Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Kunhong Xiao"'
Autor:
Fabio V, Fonseca, Thomas M, Raffay, Kunhong, Xiao, Precious J, McLaughlin, Zhaoxia, Qian, Zachary W, Grimmett, Naoko, Adachi, Benlian, Wang, Alfred, Hausladen, Brian A, Cobb, Rongli, Zhang, Douglas T, Hess, Benjamin, Gaston, Nevin A, Lambert, James D, Reynolds, Richard T, Premont, Jonathan S, Stamler
Publikováno v:
Molecular cell. 82(16)
The β
Autor:
Liwen Zhang, Jay L. Zweier, Kunhong Xiao, William M. Chilian, Chwen-Lih Chen, Patrick T. Kang, Yeong-Renn Chen
Publikováno v:
J Mol Cell Cardiol
A serious consequence of myocardial ischemia-reperfusion injury (I/R) is oxidative damage, which causes mitochondrial dysfunction. The cascading ROS can propagate and potentially induce heme bleaching and protein cysteine sulfonation (PrSO(3)H) of th
Autor:
Alex D, White, Frederic G, Jean-Alphonse, Fei, Fang, Karina A, Peña, Shi, Liu, Gabriele M, König, Asuka, Inoue, Despoina, Aslanoglou, Samuel H, Gellman, Evi, Kostenis, Kunhong, Xiao, Jean-Pierre, Vilardaga
Publikováno v:
Proc Natl Acad Sci U S A
cAMP production upon activation of G(s) by G protein-coupled receptors has classically been considered to be plasma membrane-delimited, but a shift in this paradigm has occurred in recent years with the identification of several receptors that contin
Autor:
Chia-Ling Tu, Jean-Pierre Vilardaga, Wen T. Shen, Jenna Hwong, Insoo Suh, Zhiqiang Cheng, Hongda Liu, Alfred Li, Wenhan Chang, Hanson Ho, Frederic Jean-Alphonse, Dawei Wang, Amanda Herberger, Alex D. White, Quan-Yang Duh, Elham Khanafshar, Kunhong Xiao, Dolores M. Shoback
Publikováno v:
Nature metabolism, vol 2, iss 3
Nature Metabolism
Nature Metabolism, Nature Publishing Group, 2020, 2 (3), pp.243-255. ⟨10.1038/s42255-020-0175-z⟩
Nature Metabolism
Nature Metabolism, Nature Publishing Group, 2020, 2 (3), pp.243-255. ⟨10.1038/s42255-020-0175-z⟩
International audience; Molecular mechanisms mediating tonic secretion of parathyroid hormone (PTH) in response to hypocalcaemia and hyperparathyroidism (HPT) are unclear. Here we demonstrate increased heterocomplex formation between the calcium-sens
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75977d2f606a452e5b06be8e39c54178
https://escholarship.org/uc/item/3hr9j25m
https://escholarship.org/uc/item/3hr9j25m
Autor:
Sihoon Lee, Frederic Jean-Alphonse, Hyun-Jung An, Jean-Pierre Vilardaga, Hongda Liu, Yang Zhao, Ieva Sutkeviciute, Fei Fang, Lisa J. Clark, Alex D. White, Kunhong Xiao, Shelley Reynolds
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2019, 116 (8), pp.3294-3299. ⟨10.1073/pnas.1814670116⟩
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2019, 116 (8), pp.3294-3299. ⟨10.1073/pnas.1814670116⟩
International audience; The parathyroid hormone (PTH) and its related peptide (PTHrP) activate PTH receptor (PTHR) signaling, but only the PTH sustains GS-mediated adenosine 3',5'-cyclic monophosphate (cAMP) production after PTHR internalization into
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3021fa1a36e812f8fb30fd89c463a92
https://hal.archives-ouvertes.fr/hal-03117164
https://hal.archives-ouvertes.fr/hal-03117164
Autor:
Wenhan, Chang, Chia-Ling, Tu, Frederic G, Jean-Alphonse, Amanda, Herberger, Zhiqiang, Cheng, Jenna, Hwong, Hanson, Ho, Alfred, Li, Dawei, Wang, Hongda, Liu, Alex D, White, Insoo, Suh, Wen, Shen, Quan-Yang, Duh, Elham, Khanafshar, Dolores M, Shoback, Kunhong, Xiao, Jean-Pierre, Vilardaga
Publikováno v:
Nature metabolism
Molecular mechanisms mediating tonic secretion of parathyroid hormone (PTH) in response to hypocalcemia and hyperparathyroidism (HPT) are unclear. Here we demonstrate increased heterocomplex formation between the calcium-sensing receptor (CaSR) and m
Autor:
Vanessa Saunders, Wayne Grant, Makoto R. Hara, Ainhoa Nieto, Victor Quereda, Kunhong Xiao, Patricia McDonald, Derek R. Duckett
Publikováno v:
Cell Death and Differentiation
Cellular DNA is constantly under threat from internal and external insults, consequently multiple pathways have evolved to maintain chromosomal fidelity. Our previous studies revealed that chronic stress, mediated by continuous stimulation of the β2
Autor:
Juan A. Ardura, Frederic Jean-Alphonse, W. Bruce Sneddon, Jean-Pierre Vilardaga, Tatyana Mamonova, Jennifer McGarvey, Shanna L. Bowman, Qiangmin Zhang, Alessandro Bisello, Kunhong Xiao, Peter A. Friedman, Manojkumar A. Puthenveedu
Publikováno v:
Journal of Biological Chemistry
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2016, 291 (21), pp.10986-11002. ⟨10.1074/jbc.M115.697045⟩
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2016, 291 (21), pp.10986-11002. ⟨10.1074/jbc.M115.697045⟩
International audience; The G protein-coupled parathyroid hormone receptor (PTHR) regulates mineral-ion homeostasis and bone remodeling. Upon parathyroid hormone (PTH) stimulation, the PTHR internalizes into early endosomes and subsequently traffics
Autor:
Jennifer McGarvey, W. Bruce Sneddon, Peter A. Friedman, Alessandro Bisello, Qiangmin Zhang, Hongda Liu, Kunhong Xiao, Lei Song
Publikováno v:
The Journal of biological chemistry. 293(15)
G protein–coupled receptor (GPCR) signaling and trafficking are essential for cellular function and regulated by phosphorylation, β-arrestin, and ubiquitination. The GPCR parathyroid hormone receptor (PTHR) exhibits time-dependent reversible ubiqu
Publikováno v:
Journal of Receptors and Signal Transduction. 35:213-219
Mass spectrometry (MS)-based proteomics is an unrivaled tool for studying complex biological systems and diseases in the post-genomic era. In recent years, MS has emerged as a powerful structural biological tool to characterize protein conformation a