Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Josee Gauthier"'
Autor:
Ye Yang, Raad Z. Gharaibeh, Payam Fathi, Shaoguang Wu, Liam Chung, Anthony A. Fodor, Sarah Tomkovich, Sepideh Besharati, Marcus Mühlbauer, James R. White, Jillian L. Pope, Cynthia L. Sears, Ernesto Perez-Chanona, Drew M. Pardoll, Julia L. Drewes, Kathryn Winglee, Xinqun Wu, Robert A. Anders, Christian Jobin, Franck Housseau, Christine M. Dejea, Hao Wang, Xiaolun Sun, Josee Gauthier, Xiuli Liu, Hua Ding
Publikováno v:
Journal of Clinical Investigation. 129:1699-1712
Mucus-invasive bacterial biofilms are identified on the colon mucosa of approximately 50% of colorectal cancer (CRC) patients and approximately 13% of healthy subjects. Here, we test the hypothesis that human colon biofilms comprise microbial communi
Autor:
Angela Rita Elia, Penny Flohr, Martina Troiani, Silke Gillessen, Matteo Grioni, Maria Rescigno, Alberto Briganti, Daniela Bossi, Simone Mosole, Lorenzo Buroni, Christina Guo, Christian Jobin, Anna Palmisano, Eugenia D’Antonio, Mirko Minini, Antonio Esposito, Antje Neeb, Emiliano Pasquini, Pasquale Rescigno, Jonathan Welti, Bianca Calì, Gladys Martinetti Lucchini, Jacopo Troisi, Nicolò Pernigoni, Andrea Alimonti, Giuseppe Attanasio, Sara Merler, Andrea Rinaldi, Josee Gauthier, Jean-Philippe Theurillat, Ajinkya Revandkar, Raad Z. Gharaibeh, Johann S. de Bono, Matteo Ferrari, Elena Zagato, Ricardo Pereira Mestre, Marco Bolis, Joanne Hunt, Fabio Grassi, Matteo Bellone, Arianna Calcinotto
The microbiota comprises the microorganisms that live in close contact with the host, with mutual benefit for both counterparts. The contribution of the gut microbiota to the emergence of castration-resistant prostate cancer (CRPC) has not yet been a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::244998f306451081ae48858699ac0ab9
Autor:
Mary K. Reinhard, Maria V. Guijarro, Steven J. Hughes, Anthony A. Fodor, Jillian L. Pope, Maria Zajac-Kaye, Christian Jobin, Raad Z. Gharaibeh, Rachel C. Newsome, Qin Yu, Kathryn Winglee, Jose G. Trevino, Ryan M. Thomas, Josee Gauthier, Mark Beveridge, Zhen He, Christina L. Ohland
Publikováno v:
Carcinogenesis
Pancreatic ductal adenocarcinoma (PDAC) is the third leading cause of cancer death in the United States yet data are scant regarding host factors influencing pancreatic carcinogenesis. Increasing evidence support the role of the host microbiota in ca
Autor:
Tim Wiltshire, Danielle Cunningham, Samantha K. Segall, Xia Wen, Carolina B. Meloto, Lisa M. Tarantino, Jeffrey S. Mogil, Svetlana A. Shabalina, Josee Gauthier, Sarasa Tohyama, Loren J. Martin, Luda Diatchenko
Publikováno v:
Pain
Supplemental Digital Content is Available in the Text. A functional mouse Comt allele, associated with pain behaviour, increases Comt expression by inserting an early polyadenylation signal and removing naturally occurring regulatory microRNA signals
Autor:
Xiaolun Sun, Kathryn Winglee, Zhen He, Dorina Avram, Christian Jobin, Steven D. Bruner, Anthony A. Fodor, Prabhanshu Tripathi, Josee Gauthier, Raad Z. Gharaibeh
Publikováno v:
Gastroenterology. 154(6)
Background & Aims Campylobacter jejuni, a prevalent foodborne bacterial pathogen, exploits the host innate response to induce colitis. Little is known about the roles of microbiota in C jejuni–induced intestinal inflammation. We investigated intera
Autor:
Anthony A. Fodor, Kathryn Winglee, Xiuli Liu, Ye Yang, Josee Gauthier, Mansour Mohamadzadeh, Christian Jobin, Patricia Martin, Sarah Tomkovich, Eric Oswald, Marcus Mühlbauer, Xiaolun Sun, Gary P. Wang
Publikováno v:
Cancer Research
Cancer Research, American Association for Cancer Research, 2017, 77 (10), pp.2620-2632. ⟨10.1158/0008-5472.CAN-16-3472⟩
Cancer Research 10 (77), 2620-2632. (2017)
Cancer Research, American Association for Cancer Research, 2017, 77 (10), pp.2620-2632. ⟨10.1158/0008-5472.CAN-16-3472⟩
Cancer Research 10 (77), 2620-2632. (2017)
Inflammation and microbiota are critical components of intestinal tumorigenesis. To dissect how the microbiota contributes to tumor distribution, we generated germ-free (GF) ApcMin/+and ApcMin/+;Il10−/− mice and exposed them to specific-pathogen-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72c6d0b8480a31b1402b98fec2101262
https://hal.archives-ouvertes.fr/hal-01607272
https://hal.archives-ouvertes.fr/hal-01607272
Publikováno v:
Nucleic Acids Research
Catechol-O-methyltransferase (COMT) is a major enzyme controlling catecholamine levels that plays a central role in cognition, affective mood and pain perception. There are three common COMT haplotypes in the human population reported to have functio
Comt1 genotype and expression predicts anxiety and nociceptive sensitivity in inbred strains of mice
Autor:
Laura Grabowski-Boase, Samantha K. Segall, J. S. Marron, Lisa M. Tarantino, Tim Wiltshire, Andrea G. Nackley, William R. Lariviere, Gary D. Slade, Luda Diatchenko, Josee Gauthier, Thomas M. Maynard, Janice S. Bailey, Brian M. Steffy, X. Lu, J. R. Walker
Publikováno v:
Genes, Brain and Behavior. 9:933-946
Catechol-O-methyltransferase (COMT) is an ubiquitously expressed enzyme that maintains basic biologic functions by inactivating catechol substrates. In humans, polymorphic variance at the COMT locus has been associated with modulation of pain sensiti
Autor:
Luda Diatchenko, Nikolay V. Dokholyan, Erinn L. Acland, William Maixner, Loren J. Martin, Josee Gauthier, Marjo Piltonen, Marino Convertino, Jeffrey S. Mogil
Publikováno v:
The journal of pain. 16(12)
Recent efforts have suggested that the β-adrenergic receptor (β-AR) system may be a novel and viable therapeutic target for pain reduction; however, most of the work to date has focused on the β 2 -adrenergic receptor (AR). Here, we compared the a
Autor:
Marino Convertino, Alexander Samoshkin, Luda Diatchenko, Josee Gauthier, William Maixner, Michael S. Gold, Nikolay V. Dokholyan
Publikováno v:
Progress in neuro-psychopharmacologybiological psychiatry. 62
6TM MOR is a functional isoform of μ-opioid receptor.6TM MOR has a different cellular localization with respect to 7TM-MOR.6TM MOR may signal via different cellular pathways with respect to 7TM MOR.6TM MOR stimulation may mediate excitatory cellular