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pro vyhledávání: '"Jonathan Chu"'
Publikováno v:
The Journal of animal ecologyREFERENCES. 91(8)
Substantial global data show that many taxa are shifting their phenologies in response to climate change. For birds, migration arrival dates in breeding regions have been shifting earlier, and there is evidence that both evolutionary adaptation and b
Autor:
Abhisek Bhattacharya, Alfred Singer, Jinghua Lu, Ingrid Saba, Jonathan Chu, Peter D. Sun, François Van Laethem, Anastasia N. Tikhonova
Publikováno v:
J Immunol
During normal T cell development in the thymus, αβ TCRs signal immature thymocytes to differentiate into mature T cells by binding to peptide–MHC ligands together with CD4/CD8 coreceptors. Conversely, in MHC and CD4/CD8 coreceptor-deficient mice,
Autor:
Tomer Arnon, Marco Craveiro, Nicholas C. Love, Sergei Radaev, Nan-ping Weng, Abhisek Bhattacharya, Xiaoping Sun, Jonathan Chu, Jinghua Lu, Nir Friedman, Ingrid Saba, Eric Shifrut, Anastasia N. Tikhonova, Alfred Singer, Annette Ko, Peter D. Sun, François Van Laethem
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Nature Communications
Nature Communications
The αβ T cell receptor (TCR) repertoire on mature T cells is selected in the thymus, but the basis for thymic selection of MHC-restricted TCRs from a randomly generated pre-selection repertoire is not known. Here we perform comparative repertoire s