Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Jingyi Shen"'
Publikováno v:
International immunopharmacology. 110
T-cells mediated immunopathology is crucial for pathogenesis of chronic graft-versus-host disease (cGVHD), a common complication following allogeneic hematopoietic cell transplantation. Programmed death-1 (PD-1) regulates long-term survival and funct
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology
Frontiers in Immunology
The immune system’s ability to resist the invasion of foreign pathogens and the tolerance to self-antigens are primarily centered on the efficient functions of the various subsets of T lymphocytes. As the primary organ of thymopoiesis, the thymus p
Autor:
Jun Gao, Yan Xu, Sha Ma, Yiwen Liang, Cong Liu, Jingyi Shen, Zengtian Sun, Mingshan Niu, Kailin Xu, Bin Pan
Publikováno v:
Transplantation and Cellular Therapy. 28:134.e1-134.e10
Activation of antigen-presenting cells (APCs) is crucial in initiating inflammation and alloreaction during acute graft-versus-host disease (aGVHD), a common life-threatening complication of allogeneic hematopoietic cell transplantation (allo-HCT). I
Publikováno v:
The Journal of nutritional biochemistry. 103
High-fat diets are linked to obesity, contributing to the alterations in inflammatory signaling pathways, which is associated with cognitive function. We aim to investigate the mechanisms by which various different types of dietary fatty acids affect
Autor:
Nga N. Nguyen, Justin Tai, Rhiannon Moore, Camille Goldman, Jingyi Shen, Jae H. Hur, David W. Walker, Yongchan Hong, Anil Rana
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Scientific Reports
Scientific Reports
The β5 subunit of the proteasome has been shown in worms and in human cell lines to be regulatory. In these models, β5 overexpression results in upregulation of the entire proteasome complex which is sufficient to increase proteotoxic stress resist
Publikováno v:
Mitochondrial DNA Part A. 27:4344-4346
Singidia tilapia (Oreochromis esculentus) is a native Cichlid fish of important commercial value, distributed in Lake Victoria, East Africa. Due to its declining population levels in its natural habitat, this species has now been classified as a Crit
Autor:
Dandan Zheng, Lejiao Jia, Qiang Zhang, Xiaona Tian, Jingyi Shen, Zhenyu Li, Guangpu Liu, Dianrui Zhang
Publikováno v:
International Journal of Pharmaceutics. 445:12-19
In the present study, mesoporous silica nanoparticles (MSNs) with three pore size were manufactured by the etch method. A typical chemotherapeutic agent, paclitaxel (PTX) was loaded into these MSNs. The in vitro drug release behavior, the in vitro an
Autor:
Yue Liu, Lejiao Jia, Jingyi Shen, Dandan Zheng, Hejian Guo, Xiaona Tian, Qiang Zhang, Caiyun Li, Hongxiang Lou, Cunxian Duan, Dianrui Zhang, Yang Jiao, Guangpu Liu
Publikováno v:
Colloids and Surfaces B: Biointerfaces. 102:620-626
Riccardin D (RD) is a novel compound extracted from Chinese liverwort Marchantia polymorpha L. It exhibits various anticancer activities and can be used during lung cancer treatment. However, the compound's low solubility hinders its development. Rec
Autor:
Leilei Hao, Caiyun Li, Hejian Guo, Qiang Zhang, Dianrui Zhang, Tingting Li, Jingyi Shen, Xinquan Liu, Guangpu Liu, Lisi Qi, Yuanyuan Guo, Jingjing Luan
Publikováno v:
Journal of pharmaceutical sciences. 103(3)
A liver-targeting drug delivery system for doxorubicin (DOX), that is, DOX-loaded self-assembled nanoparticles based on galactosylated O-carboxymethyl chitosan-graft-stearic acid conjugates (Gal-OS/DOX), has been prepared. The objective of the presen
Autor:
Caiyun Li, Qiang Zhang, Leilei Hao, Jingyi Shen, Hejian Guo, Lejiao Jia, Dandan Zheng, Dianrui Zhang, Zhongxi Zhao, Guangpu Liu, Xiaona Tian
Publikováno v:
International journal of pharmaceutics. 456(1)
Oridonin (ORI), a diterpenoid compound with promising antitumor activity, was proved to possess potent antileukemia efficacies in vitro and in vivo recently. However, the development and application of ORI was limited by its poor solubility and rapid