Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Jingsheng Lou"'
Autor:
Yu Guo, Yan Zhang, Jun Wang, Jinjun Bian, Miaomiao Fei, Xiaoming Deng, Jingsheng Lou, Jiafeng Wang
Publikováno v:
The Journal of Infectious Diseases. 222:1051-1061
Background Lymphocyte activation gene 3 (LAG-3) is one of the immune checkpoint molecules, negatively regulating the T-cell reactions. The present study investigated the role of LAG-3 in sepsis-induced T-lymphocyte disability. Methods Mice sepsis was
Autor:
Xiaowen Sun, Xuehui Zhang, Yunyang Bai, Li Sun, Jing Zhang, Boon Chin Heng, Baowei Li, Min Gao, Xuliang Deng, Teliang Lu, Weiwei Liang, Jingsheng Lou, Jiandong Ye
Publikováno v:
Journal of Materials Chemistry B. 8:3038-3049
Integrating multiple pro-osteogenic factors into bone graft substitutes is a practical and effective approach to improve bone repair efficacy. Here, Si-Zn dual elements and PLGA microspheres were incorporated into calcium phosphate cement (CPC) scaff
Autor:
Bo Ye, Tianzhu Tao, Weidong Mi, Qiang Fu, Jingsheng Lou, Andong Zhao, Yi Liu, Liyuan Wen, Xiaofei He
Publikováno v:
Mediators of Inflammation
Mediators of Inflammation, Vol 2019 (2019)
Mediators of Inflammation, Vol 2019 (2019)
Sepsis-associated encephalopathy (SAE) is a poorly understood condition that leads to long-term cognitive impairment and increased mortality in survivors. Recent research revealed that IL-17A/IL-17R might serve as a checkpoint in microglia-mediated n
Autor:
Long‑He Xu, Xuan Zhang, Yu‑Ge Jiang, Xue‑Yin Shi, Wei‑Dong Mi, Jian Tan, Li Sun, Jingsheng Lou, Hao Li
Publikováno v:
Molecular medicine reports. 17(3)
Propofol postconditioning (P‑PostC) offers cardioprotection in mice, and the upregulation of autophagy protects cardiac cells against ischemia/reperfusion injury. The present study aimed to examine the effects of P‑PostC on the induction of autop
Autor:
Youping Wu, Jiali Zhu, Rui Bao, Ying Sheng, Lulong Bo, Jiafeng Wang, Fei Wang, Xiaoming Deng, Feng Chen, Jingsheng Lou, Jinbao Li, Yun Zou, Xiaohua Fan
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e35523 (2012)
PLoS ONE
PLoS ONE
BACKGROUND: An imbalance between overwhelming inflammation and lymphocyte apoptosis is the main cause of high mortality in patients with sepsis. Baicalin, the main active ingredient of the Scutellaria root, exerts anti-inflammatory, anti-apoptotic, a
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e46506 (2012)
PLoS ONE
PLoS ONE
Purpose The current study aimed to elucidate the role of peritoneal fluid IL-17A in septic mice, and the effects of intraperitoneal or intravenous blockade of the IL-17A pathway by anti-IL17A antibody on survival, plasma, and peritoneal cavity cytoki
Autor:
Xiaojian Wan, Ke-ming Zhu, Zailong Cai, Ying Zhou, Jingsheng Lou, Lulong Bo, Xiao-ming Deng, Yan-Yan Zhang, Jinbao Li
Publikováno v:
Critical Care
Introduction Lymphocyte apoptosis and monocyte dysfunction play a pivotal role in sepsis-induced immunosuppression. Programmed death-1 (PD1) and its ligand programmed death ligand-1 (PD-L1) exert inhibitory function by regulating the balance among T