Zobrazeno 1 - 10
of 121
pro vyhledávání: '"Jee H. Jung"'
Publikováno v:
Marine drugs. 20(3)
Through activity-guided fractionation, a new triterpene (asperflagin
Autor:
Suhkmann Kim, Jongki Hong, Eun La Kim, Hae Young Chung, Zhiran Ju, Jee H. Jung, Hyung Ryong Moon, Mingzhi Su
Publikováno v:
European Journal of Medicinal Chemistry. 180:86-98
The aim of this study was to design and synthesize COX-1/COX-2 balanced inhibitors incorporating the structural motifs of anti-inflammatory ascidian metabolites. We designed a series of substituted indole analogs that incorporate the key structures o
Publikováno v:
Bioorganic chemistry. 96
In our previous study, a PPAR-γ agonist (+)-(R,E)-6a1 was elaborated as an anti-inflammatory lead. However, in silico analysis showed that (+)-(R,E)-6a1 lacks key hydrogen bonding with Tyr473 of PPAR-γ LBD (ligand binding domain). To facilitate add
Publikováno v:
Journal of Natural Products. 81:356-363
An investigation of the jellyfish-derived fungus Penicillium chrysogenum J08NF-4 led to the isolation of two new meroterpene derivatives, chrysogenester (1) and 5-farnesyl-2-methyl-1-O-methylhydroquinone (2), and four known farnesyl meroterpenes. Doc
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 27:4970-4974
Viriditoxin is a fungal secondary metabolite of the fungus Paecilomyces variotii derived from the inner tissues of the giant jellyfish Nemopilema nomurai. Viriditoxin exhibits antibacterial activity against Streptococcus iniae and Streptococcus parau
Publikováno v:
Marine Drugs
Marine Drugs, Vol 19, Iss 417, p 417 (2021)
Volume 19
Issue 8
Marine Drugs, Vol 19, Iss 417, p 417 (2021)
Volume 19
Issue 8
Peroxisome proliferator-activated receptor (PPAR) expression has been implicated in pathological states such as cancer, inflammation, diabetes, and neurodegeneration. We isolated natural PPAR agonists—eight 2,5-diketopiperazines—from the jellyfis
Publikováno v:
Natural Product Research. 31:1682-1686
Two new metabolites, diorcinolic acid (1) and β-d-glucopyranosyl aspergillusene A (8), together with six diphenylethers (2–7), a diketopiperazine (9), a chromone (10) and a xanthone (11) were isolated from the fungus Aspergillus sydowii derived fr
Autor:
Zhiran Ju, Jongki Hong, Dan-Dan Li, Mingzhi Su, Suhkmann Kim, Dong-Soon Im, Eun La Kim, Jee H. Jung
Publikováno v:
Marine Drugs
Volume 17
Issue 6
Marine Drugs, Vol 17, Iss 6, p 321 (2019)
Volume 17
Issue 6
Marine Drugs, Vol 17, Iss 6, p 321 (2019)
In our previous study, a synthetic compound, (+)-(R,E)-6a1, that incorporated the key structures of anti-inflammatory algal metabolites and the endogenous peroxisome proliferator-activated receptor &gamma
(PPAR-&gamma
) ligand 15-deoxy-∆1
(PPAR-&gamma
) ligand 15-deoxy-∆1
Publikováno v:
Molecular Medicine Reports. 14:2691-2696
Vibrio vulnificus is known to induce severely fulminant and fatal septicemia in susceptible hosts. In the present study, the antimicrobial activity of natural marine product-derived compounds against V. vulnificus, were investigated in vitro and in v
Autor:
Saeromi Kang, Dong-Soon Im, Jung-Min Kim, Jee H. Jung, Young-Geun Lee, Jung-Min Lee, Kyoung-Pil Lee, Soo-Jin Park, Hyung Ryong Moon, Young-Whan Choi
Publikováno v:
Journal of Ethnopharmacology. 178:17-24
Ethnopharmacological relevance The giant butterbur Petasites japonicus is used to treat asthma and allergic diseases in traditional Korean, Japanese, and Chinese medicine. Aim of the study To elucidate the anti-allergic effect of Petasites genus, we