Zobrazeno 1 - 10
of 430
pro vyhledávání: '"J Wong"'
Publikováno v:
Journal of visualized experiments : JoVE. (190)
Growing evidence suggests that the sympathetic nervous system plays an important role in cancer progression. Adrenergic innervation regulates salivary gland secretion, circadian rhythm, macular degeneration, immune function, and cardiac physiology. M
Autor:
Myles Brown, X. Shirley Liu, Dian Li, Robert T. Manguso, Lin Yang, Kathleen B. Yates, Sarah Kim, Cheryl J Wong, Ravindra Uppaluri, Gordon J. Freeman, Shengqing Gu, Liye Zhou, Jingxin Fu, Yi Zhang, Zexian Zeng, Wubing Zhang, Boning Zhang, Yang Liu, Xiaoqing Wang, Nofal Ouardaoui
Publikováno v:
Nucleic Acids Research
Syngeneic mouse models are tumors derived from murine cancer cells engrafted on genetically identical mouse strains. They are widely used tools for studying tumor immunity and immunotherapy response in the context of a fully functional murine immune
Autor:
Guanghan Meng, Jian Zhong, Qinrong Zhang, Justin S. J. Wong, Jianglai Wu, Kevin K. Tsia, Na Ji
Publikováno v:
Proceedings of the National Academy of Sciences. 119
Characterizing blood flow dynamics in vivo is critical to understanding the function of the vascular network under physiological and pathological conditions. Existing methods for hemodynamic imaging have insufficient spatial and temporal resolution t
Autor:
Alessia Fornoni, Leopoldo Raij, Surya V. Seshan, Evren U. Azeloglu, Gabriel Rezonzew, Ming Sheng Zhou, Alecia N. Muwonge, Run-Xia Tian, Edgar A. Jaimes, Sandra Merscher, Mohammed Siddiqui, Nicholas J. Wong
Publikováno v:
Am J Physiol Renal Physiol
Diabetic nephropathy (DN) is the leading cause of end-stage kidney disease. Besides glycemic and blood pressure control, environmental factors such as cigarette smoking (CS) adversely affect the progression of DN. The effects of CS on DN progression
Autor:
Tonya Bongolan, Jennifer Whiteley, Jorge Castillo-Prado, Amanda Fantin, Brett Larsen, Cassandra J. Wong, Laura Mazilescu, Masataka Kawamura, Peter Urbanellis, Anna Jonebring, Eric Salter, Graham Collingridge, Rebecca Gladdy, Ryan Hicks, Anne-Claude Gingras, Markus Selzner, Ian M. Rogers
Publikováno v:
Biomaterials science. 10(11)
When decellularizing kidneys, it is important to maintain the integrity of the acellular extracellular matrix (ECM), including associated adhesion proteins and growth factors that allow recellularized cells to adhere and migrate according to ECM spec
Autor:
Mridul Agrawal, Abhishek Niroula, Pierre Cunin, Marie McConkey, Veronica Shkolnik, Peter G. Kim, Waihay J. Wong, Lachelle D. Weeks, Amy E. Lin, Peter G. Miller, Christopher J. Gibson, Aswin Sekar, Inga-Marie Schaefer, Donna Neuberg, Richard M. Stone, Alexander G. Bick, Md Mesbah Uddin, Gabriel K. Griffin, Siddhartha Jaiswal, Pradeep Natarajan, Peter A. Nigrovic, Deepak A. Rao, Benjamin L. Ebert
Publikováno v:
Blood. 140(10)
Gout is a common inflammatory arthritis caused by precipitation of monosodium urate (MSU) crystals in individuals with hyperuricemia. Acute flares are accompanied by secretion of proinflammatory cytokines, including interleukin-1β (IL-1β). Clonal h
Low‐dose lipopolysaccharide exposure can increase in vivo bilirubin production rates in newborn mice
Publikováno v:
Acta Paediatrica. 109:1551-1559
AIM Neonatal haemolysis increases bilirubin production rates, which can then lead to severe hyperbilirubinaemia and bilirubin neurotoxicity. During haemolysis, haem is degraded by haem oxygenase (HO), which can be induced under stress conditions. It
Autor:
Benjamin L. Ebert, David M. Evans, Mridul Agrawal, Veronica Shkolnik, Douglas P. Kiel, Christopher J. Gibson, Marie McConkey, Mesbah Uddin, Wesley J. Shin, Abhishek Niroula, Drew N. Cohen, James P. Pirruccello, Pradeep Natarajan, Mikolaj Slabicki, Mary L. Bouxsein, Alexander G. Bick, Waihay J. Wong, Gabriel K. Griffin, Daniel J. Brooks, Peter Geon Kim, Aswin Sekar, Julia F. Charles, J. Brent Richards, Amy E. Lin, Jonathan M. Tsai, Marc N. Wein, John P. Kemp, Siddhartha Jaiswal
Publikováno v:
The Journal of experimental medicine. 218(12)
Osteoporosis is caused by an imbalance of osteoclasts and osteoblasts, occurring in close proximity to hematopoietic cells in the bone marrow. Recurrent somatic mutations that lead to an expanded population of mutant blood cells is termed clonal hema
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 9675, p 9675 (2021)
International Journal of Molecular Sciences, Vol 22, Iss 9675, p 9675 (2021)
Oxygen levels in the placental microenvironment throughout gestation are not constant, with severe hypoxic conditions present during the first trimester. This hypoxic phase overlaps with the most critical stages of placental development, i.e., blasto
Autor:
Jonathan D. Reiss, Laura S. Peterson, Sophia N. Nesamoney, Alan L. Chang, Anca M. Pasca, Ivana Marić, Gary M. Shaw, Brice Gaudilliere, Ronald J. Wong, Karl G. Sylvester, Sonia L. Bonifacio, Nima Aghaeepour, Ronald S. Gibbs, David K. Stevenson
Publikováno v:
Experimental neurology. 351
Preterm newborns are exposed to several risk factors for developing brain injury. Clinical studies have suggested that the presence of intrauterine infection is a consistent risk factor for preterm birth and white matter injury. Animal models have co