Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Fengyi Wan"'
Publikováno v:
Infect Immun
Enteropathogenic Escherichia coli (EPEC) and enterohemorrhagic E. coli (EHEC) are important causative agents for foodborne diseases worldwide. Besides antibiotic treatment, vaccination has been deemed as the most effective strategy for preventing EPE
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::798884e9294f029eeefb5a896d6d4c82
https://europepmc.org/articles/PMC9302154/
https://europepmc.org/articles/PMC9302154/
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Our study highlights that hemochromatotic hosts are susceptible to the siderophilic enteropathogenic Yersinia because of dysregulated interleukn (IL)-1β signaling that causes rapid disruption of the intestinal tight junction, leading to
Publikováno v:
Cancer Medicine, Vol 8, Iss 13, Pp 6106-6113 (2019)
Cancer Medicine
Cancer Medicine
Although targeting DNA repair signaling pathways has emerged as a promising therapeutic for skin cancer, the relevance of DNA damage responses (DDR) in the development and survival of nonmelanoma skin cancer (NMSC), the most common type of skin cance
Autor:
Julia L. Drewes, Jie Chen, Nicholas O. Markham, Reece J. Knippel, Jada C. Domingue, Ada J. Tam, June L. Chan, Lana Kim, Madison McMann, Courtney Stevens, Christine M. Dejea, Sarah Tomkovich, John Michel, James R. White, Fuad Mohammad, Victoria L. Campodónico, Cody N. Heiser, Xinqun Wu, Shaoguang Wu, Hua Ding, Patricia Simner, Karen Carroll, Martha J. Shrubsole, Robert A. Anders, Seth T. Walk, Christian Jobin, Fengyi Wan, Robert J. Coffey, Franck Housseau, Ken S. Lau, Cynthia L. Sears
Publikováno v:
Cancer discovery. 12(8)
Defining the complex role of the microbiome in colorectal cancer and the discovery of novel, protumorigenic microbes are areas of active investigation. In the present study, culturing and reassociation experiments revealed that toxigenic strains of C
Autor:
Eric M. Wier, Xue Xia, Andrea Hodgson, Dongqing Xu, Jian Yang, Yue Liu, Cynthia L. Sears, Hua Ding, Yifan Lei, Kai Fu, Fengyi Wan, Dandan Zheng
Publikováno v:
Cancer Discov
Chronic and low-grade inflammation associated with persistent bacterial infections has been linked to colon tumor development; however, the impact of transient and self-limited infections in bacterially driven colon tumorigenesis has remained enigmat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa572dbb0c3451087102884c6697d25a
https://europepmc.org/articles/PMC8758537/
https://europepmc.org/articles/PMC8758537/
Publikováno v:
Experimental physiologyREFERENCES. 106(12)
New findings What is the central question of this study? The physiological implication of MrgprD in gastrointestinal motility is unknown. The aim of this study is to assess the effects of MrgprD and its receptor agonists on murine gastrointestinal mo
Autor:
Fengyi Wan, Sarah L. J. Michel, Shaoguang Wu, Joanna M.P. Melia, Talin Haritunians, Xinqun Wu, Cynthia L. Sears, Sodbo Zh Sharapov, Laxmi Sunuwar, Heather M. Neu, Azra Frkatović, Mark Donowitz, Gordan Lauc, Qinchuan Wang, Dermot P.B. McGovern
Publikováno v:
JCI Insight, Vol 5, Iss 20 (2020)
JCI Insight
JCI Insight
ZIP8 is a metal transporter with a role in manganese (Mn) homeostasis. A common genetic variant in ZIP8 (rs13107325; A391T) ranks in the top 10 of pleiotropic SNPs identified in GWAS; A391T has associations with an increased risk of schizophrenia, ob
Autor:
Hao Su, Weijie Zhang, Richard Oh, Fengyi Wan, Caleb F. Anderson, Honggang Cui, Zongyuan Wang, Wenbing Dai, Feihu Wang, Mengzhen Zheng, Dongqing Xu
Publikováno v:
Nat Biomed Eng
Tumours with an immunosuppressive microenvironment respond poorly to therapy. Activation of the stimulator of interferon genes (STING) pathway can enhance intratumoural immune activation, but STING agonists are associated with high toxicity and degra
Publikováno v:
Cell and Tissue Research
MrgprD, a Mas-related G protein-coupled receptor, is initially identified in sensory neurons of mouse dorsal root ganglia (DRG) and has been suggested to participate in somatosensation. However, MrgprD has recently been found to be expressed outside
Sporadic colorectal cancer is one of the most common and lethal cancers worldwide. The locations and functions of immune cells in the colorectal tumor microenvironment are complex and heterogeneous. T-helper (Th)1 cell–mediated responses against es
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::080a726a2b8ec63fcb8aeccc52463245
https://europepmc.org/articles/PMC6441974/
https://europepmc.org/articles/PMC6441974/