Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Fan Li Lin"'
Autor:
Jiang-Hui Wang, Ching-Li Tseng, Fan-Li Lin, Jinying Chen, Erh-Hsuan Hsieh, Suraj Lama, Yu-Fan Chuang, Satheesh Kumar, Linxin Zhu, Myra B. McGuinness, Jessika Hernandez, Leilei Tu, Peng-Yuan Wang, Guei-Sheung Liu
Publikováno v:
Theranostics
Rationale: Corneal neovascularization (CoNV) is a severe complication of various types of corneal diseases, that leads to permanent visual impairment. Current treatments for CoNV, such as steroids or anti-vascular endothelial growth factor agents, ar
Autor:
Jiang-Hui Wang, Yu-Fan Chuang, Jinying Chen, Vikrant Singh, Fan-Li Lin, Richard Wilson, Leilei Tu, Chenkai Ma, Raymond C.B. Wong, Peng-Yuan Wang, Jingxiang Zhong, Alex W. Hewitt, Peter van Wijngaarden, Gregory J. Dusting, Guei-Sheung Liu
Publikováno v:
Nucleic acid therapeutics. 32(4)
Retinal neovascularization is a severe complication of proliferative diabetic retinopathy (PDR). MicroRNAs (miRNAs) are master regulators of gene expression that play an important role in retinal neovascularization. In this study, we show that miR-14
Autor:
Jiang-Hui Wang, Yu-Fan Chuang, Vickie H. Y. Wong, Guei-Sheung Liu, Bang V. Bui, Fan-Li Lin, Peng-Yuan Wang
Publikováno v:
Mol Ther
Aberrant growth of blood vessels (neovascularization) is a key feature of severe eye diseases that can cause legal blindness, including neovascular age-related macular degeneration (nAMD) and diabetic retinopathy (DR). The development of anti-vascula
Autor:
George Hsiao, Chi Hao Tsai, Tai Ju Hsu, Zuha Imtiyaz, Kunal Nepali, Fan Li Lin, Yu Wen Cheng, Mei Jung Lai
Publikováno v:
Molecules, Vol 26, Iss 4359, p 4359 (2021)
Molecules
Volume 26
Issue 14
Molecules
Volume 26
Issue 14
Age-related macular degeneration (AMD) occurs due to an abnormality of retinal pigment epithelium (RPE) cells that leads to gradual degeneration of the macula. Currently, AMD drug pipelines are endowed with limited options, and anti-VEGF agents stand
Autor:
Mong Heng Wang, Shu Hsien Huang, Jing Lun Yen, Fan Li Lin, Chih Kuang Chen, Ping Huei Tsai, Po Jen Hsueh, Che Jen Hsiao, Yueh-Hsiung Kuo, George Hsiao
Publikováno v:
Molecules, Vol 26, Iss 2970, p 2970 (2021)
Molecules
Volume 26
Issue 10
Molecules
Volume 26
Issue 10
Intracerebral hemorrhage (ICH) is a devastating neurological disorder characterized by an exacerbation of neuroinflammation and neuronal injury, for which few effective therapies are available at present. Inhibition of excessive neuroglial activation
Autor:
Fan Li Lin, George Hsiao, Yu Wen Cheng, Yu Cheng Kuo, Tzong-Huei Lee, Jau Der Ho, George C.Y. Chiou, Hung Ming Chang, Min Yu
Publikováno v:
Phytomedicine. 56:207-214
Background Elevated intraocular pressure (IOP) is a major risk factor for glaucoma that has been found to induce matrix metalloproteinase-9 (MMP-9) activation and result in eventual retinal dysfunction. Proinflammatory cytokines such as monocyte chem
Autor:
Ching Yi Chen, Jau Der Ho, Ching Hao Li, Fan Li Lin, Po Lin Liao, Yu Wen Cheng, Chi Hao Tsai, Yen Ju Chan
Publikováno v:
Particle and Fibre Toxicology
Particle and Fibre Toxicology, Vol 18, Iss 1, Pp 1-16 (2021)
Particle and Fibre Toxicology, Vol 18, Iss 1, Pp 1-16 (2021)
Background Depending on their distinct properties, titanium dioxide nanoparticles (TiO2-NPs) are manufactured extensively and widely present in our daily necessities, with growing environmental release and public concerns. In sunscreen formulations,
Autor:
Jinying, Chen, Fan-Li, Lin, Jacqueline Y K, Leung, Leilei, Tu, Jiang-Hui, Wang, Yu-Fan, Chuang, Fan, Li, Hsin-Hui, Shen, Gregory J, Dusting, Vickie H Y, Wong, Leszek, Lisowski, Alex W, Hewitt, Bang V, Bui, Jingxiang, Zhong, Guei-Sheung, Liu
Publikováno v:
Angiogenesis. 24(1)
Gene therapies that chronically suppress vascular endothelial growth factor (VEGF) represent a new approach for managing retinal vascular leakage and neovascularization. However, constitutive suppression of VEGF in the eye may have deleterious side e
Autor:
Hui Wen Cheng, Fan Li Lin, Shih Hsuan Huang, Cheng Hui Lin, Ching Hao Li, George Hsiao, Yu Wen Cheng, Jau Der Ho, Chi Hao Tsai, Man Ru Wu, Jaw Jou Kang
Publikováno v:
Toxicological Sciences. 157:196-210
Blue light-induced phototoxicity plays an important role in retinal degeneration and might cause damage as a consequence of smartphone dependency. Here, we investigated the effects of periodic exposure to blue light-emitting diode in a cell model and
Autor:
Fan-Li, Lin, Yi, Qian, Min, Yang, Shu-Yue, Wang, Xiao-Qing, Chen, Yan, Cheng, Hao, Xiong, Chun-Lan, Huang
Publikováno v:
Zhongguo shi yan xue ye xue za zhi. 27(2)
To investigate the effect of microvascular endothelial cells (MEC) on the proliferation of hematopoictic stem cells (HSC) under different culture conditions in vitro.The MEC from lung tissue of C57BL/6 mice and the HSC from bone marrow of GFP mice we