Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Fan, Hao"'
Publikováno v:
Human Reproduction. 36:3049-3061
STUDY QUESTIONIs the protein l-arginine methyltransferase 3 (PRMT3)/asymmetrical dimethylarginine (ADMA)/nitric oxide (NO) pathway involved in the development of recurrent miscarriage (RM), and what is the potential mechanism?SUMMARY ANSWERElevated l
Autor:
Yu-heng Li, Kai-li Liu, Fan-hao Meng, De-pu Wang, Wen-han Xue, Qi-qi Lin, Shuai Li, Xin-yang Li, Xin-hua Qian
Publikováno v:
Journal of Medicinal Chemistry. 64:13356-13372
Based on the novel allosteric site of deoxyhypusine synthase (DHPS), two series of 30 novel 5-(2-methoxyphenoxy)-2-phenylpyrimidin-4-amine derivatives as DHPS inhibitors were designed and synthesized. Among them, compound 8m, with the best DHPS inhib
Autor:
Hao Zhou, Zhaofan Xia, Wang Guangyi, Jin Jian, Chen Zhengli, Shihui Zhu, Tang Tao, Bing Ma, Xudong Hong, Fan Hao, Zhang Xudong
Publikováno v:
Journal of Burn Care & Research. 43:445-452
Both silicone gel and quercetin are effective in scar treatment but have different action mechanisms. Quercetin is mainly applied in the gel form and can lead to poor adhesion of silicone gel sheet; therefore, they cannot be combined in clinical use.
Publikováno v:
Frontiers in Endocrinology. 13
Adenomyosis is a common benign uterine lesion that is associated with female infertility, reduced clinical pregnancy rate and high miscarriage risk. While it has been known that the impaired endometrial receptivity is implicated in infertility in pat
Autor:
Xudong Hong, Jian Jin, Chen Aifen, Zhaofan Xia, Hu Xiaoyan, Xingxia Wang, Guangyi Wang, Fan Hao, Zhang Xudong
Publikováno v:
Wound Repair and Regeneration. 28:797-811
This study aimed to improve the conventional rat burn wound model and to validate its utility. In total, 60 Sprague-Dawley rats were divided equally into the control and experimental groups. Altogether, 60 burn wound models with zones of stasis were
Autor:
Xiao-Guang Tian, Fei-Fei Gong, Xi Li, Fan-Hao Meng, Zheng Zhou, Hai-Zhong Zhang, Ning-Ning Wang
Publikováno v:
Chinese Medical Journal
Chinese Medical Journal, Vol 133, Iss 16, Pp 1935-1942 (2020)
Chinese Medical Journal, Vol 133, Iss 16, Pp 1935-1942 (2020)
Background. The casein kinase 2-interacting protein-1 (CKIP-1) is important in the development of osteoblasts and cardiomyocytes. However, the effects of CKIP-1 on osteoblast precursor mesenchymal stem cells (MSCs) remain unclear. This study aimed to
Autor:
Guangyi Wang, Chen Zhengli, Tang Tao, Bing Ma, Xudong Hong, Fan Hao, Zhaofan Xia, Zhang Xudong, Pengfei Luo, Hao Zhou, Jian Jin, Yang Xiang
Publikováno v:
Wound Repair and Regeneration. 28:480-492
Current wound scaffold dressing constructs can facilitate wound healing but do not exhibit antibacterial activity, resulting in high infection rates. We aimed to endow wound scaffold dressing with anti-infective ability by polyhexamethylenebiguanide
Publikováno v:
ACS applied materialsinterfaces. 13(39)
Smart response hydrogel has a broad application prospect in human health real-time monitoring due to its responses to a variety of stimuli. In this study, we developed a novel smart hydrogel dressing based on conductive MXene nanosheets and a tempera
Autor:
Ting-Jian, Zhang, Zhen-Hao, Zhang, Xu, Zhang, Zhao-Ran, Wang, En-Yu, Xu, Shun, Tu, Yi, Zhang, Fan-Hao, Meng
Publikováno v:
Bioorganic Chemistry. 127:105938
Xanthine oxidase (XO) is a flavoprotein that exists in various organisms and can catalyze the uric acid formation in the human body. Based on the amide framework of N-(4-((3-cyanobenzyl)oxy)-3-(1H-tetrazol-1-yl)phenyl)isonicotinamide (compound 1) rep
Autor:
Chakroborty, Debanjan, Goswami, Sandeep, Fan, Hao, Frankel, Wendy L., Basu, Sujit, Sarkar, Chandrani
Publikováno v:
British Journal of Cancer; Nov2022, Vol. 127 Issue 8, p1440-1449, 10p