Zobrazeno 241 - 250
of 96 223
pro vyhledávání: '"Diabetes Mellitus"'
Autor:
Sixuan, Wang, Jun, Duan, Jiangquan, Liao, Yan, Wang, Xiang, Xiao, Lin, Li, Yi, Liu, Huan, Gu, Peng, Yang, Dongliang, Fu, Jinhang, Du, Xianlun, Li, Mingjing, Shao
Publikováno v:
Aging. 14:6809-6828
Extensive studies have shown that ERS may be implicated in the pathogenesis of DCM. We explored the therapeutic effects of lncRNAH19 on DCM and its effect on ERS-associated cardiomyocyte apoptosis.C57/BL-6j mice were randomly divided into 3 groups: n
Publikováno v:
Kardiologiia. 62:33-37
The cardiohemodynamics was studied 1 week after the administration of streptozotocin (60 mg / kg) or 2 weeks after a dose of 30 mg / kg. All rats had a significantly elevated level of glucose in the blood (up to 27—31 mM). In an echocardiographic s
Publikováno v:
Biotechnology Letters. 44:1149-1162
We constructed a recombinant oral GLP-1 analogue in Lactococcus lactis (L. lactis) and evaluated its physiological functions.In silico docking suggested the alanine at position 8 substituted with serine (A8SGLP-1) reduced binding of DPP4, which trans
Autor:
Jie Mei, Huixiang Tian, Hsuan-Shun Huang, Nayiyuan Wu, Yu-Ligh Liou, Tang-Yuan Chu, Jing Wang, Wei Zhang
Publikováno v:
Cell Cycle. 22:85-99
High-grade serous ovarian cancer (HGSOC) is the most common and malignant type of ovarian cancer, accounting for 70%-80% of mortality. However, the treatment of HGSOC has improved little in the past few decades. Metformin is the first-line medication
Publikováno v:
Journal of Medical Primatology. 51:355-366
Using untargeted metabolomics techniques, the goal of the study is to differentially screen serum and feces metabolite profiles of spontaneously diabetic and healthy cynomolgus monkeys, to explore potential serum and fecal biomarkers and analyze affe
Autor:
Maryam Mousavi, Nasim Abedimanesh, Kosar Mohammadnejad, Elham Sharini, Maryam Nikkhah, Mohammad Reza Eskandari, Behrooz Motlagh, Javad Mohammadnejad, Hadi Khodabandehloo, Mojtaba Fathi, Moosa Talebi
Publikováno v:
Molecular Biology Reports. 49:9345-9354
Continuing hyperglycemia causes and exacerbate oxidative stress. Betanin as the principal pigment of red beet root has antioxidant, anti-inflammatory, and anti-diabetic properties. The purpose of this study was to investigate the potency of betanin o
Publikováno v:
Molecular Neurobiology. 59:6666-6683
The purpose of this study is to explore the effect and mechanism of neuritin overexpression in the bone marrow on peripheral neuropathy in type 2 diabetic (db/db) mice. We analyzed the impact of bone marrow neuritin overexpression on diabetic periphe
Autor:
Camila Espasandín, Sofía Rivero, Laura Bengoa, Karina Cal, Gerardo Romanelli, Juan Claudio Benech, Juan Pablo Damián
Publikováno v:
Experimental Brain Research. 240:2687-2699
Individuals with diabetes mellitus (DM) tend to manifest anxiety and depression, which could be related to changes in the expression of calcium/calmodulin-dependent protein kinase IV (CaMKIV), transcription factor cyclic AMP-responsive element bindin
Publikováno v:
Journal of Small Animal Practice. 63:809-815
Diabetes mellitus is a common condition that requires intensive treatment and markedly impacts the welfare of affected cats. The aim of this study was to identify diabetes mellitus-associated perturbations in the feline pancreatic islet microenvironm
Publikováno v:
Cell Stress Chaperones
Diabetic peripheral neuropathy (DPN) is a common nerve disorder of diabetes. The aim of this study was to explore the protective effects of tropisetron in DPN. Type 1 diabetes was created by a single injection of streptozotocin (50 mg/kg, ip). Tropis