Zobrazeno 1 - 10
of 15
pro vyhledávání: '"C. Vermeer"'
Autor:
L J, Schurgers, C, Vermeer
Publikováno v:
Journal of lipid research. 42(7)
In this article we report the effects of low and high fat diets on the arterial thrombosis tendency in rats. The animal system used was the aorta loop model, in which we compared the effect of saturated (hardened coconut oil, HCO) and unsaturated (su
Publikováno v:
The British journal of nutrition. 83(2)
The aim of the present study was to assess how high doses of dietary vitamin K influence the intestinal profile of K-vitamins in vitamin K-deficient rats, and whether the induced changes are reflected in the hepatic vitamin K store. Vitamin K-deficie
Publikováno v:
Methods in enzymology. 282
Publikováno v:
The Journal of biological chemistry. 268(12)
Vitamin K-dependent carboxylase, purified from bovine liver, has properties similar to those reported for the carboxylase activity present in crude, solubilized microsomes. The purified carboxylase was found to possess the vitamin K epoxidase activit
Publikováno v:
Thrombosis and haemostasis. 68(5)
Two Devon Rex cats from the same litter, which had no evidence of liver disease, malabsorption of vitamin K or chronic ingestion of coumarin derivatives, were found to have plasma deficiencies of factors II, VII, IX and X. Oral treatment with vitamin
Publikováno v:
Thrombosis and haemostasis. 57(1)
The in vitro vitamin K-dependent carboxylation of peptide- or protein-bound glutamate residues is generally studied in detergent-solubilized microsomes from rat or cow liver. Under the conditions usually employed, the efficiency of the carboxylation
Publikováno v:
Bibliotheca haematologica. 44
Publikováno v:
Biochemical pharmacology. 35(19)
This study reports an increased susceptibility to warfarin anticoagulation in mice bearing an experimental tumour, the Lewis lung carcinoma. In these animals, following a single i.v. injection of warfarin, the prothrombin complex activity decreased n
Publikováno v:
FEBS letters. 222(2)
In the liver vitamin K epoxide, which is produced during the posttranslational carboxylation of proteinbound glutamic acid residues, is recycled by the action of one or more dithiol-dependent reductases. In vitro synthetic dithiols may serve as a cof
Publikováno v:
The Journal of biological chemistry. 257(10)
In addition to the three known forms of vitamin K (vitamin K quinone, vitamin K hydroquinone, and vitamin K epoxide), a fourth metabolite, hydroxyvitamin K, was found in reaction mixtures containing a vitamin K-dependent carboxylating enzyme system.