Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Boris Melloni"'
Publikováno v:
Thorax. 51:781-786
BACKGROUND: The proliferative response of type II cells is an important event following silica-induced lung injury. Alveolar macrophages, when activated by fibrogenic agents, secrete various biological mediators which affect cell growth. METHODS: Hum
Publikováno v:
Journal of Leukocyte Biology. 55:574-580
The proliferation of lung epithelial cells is a prominent feature of lung tissue response following silica-induced lung injury and alveolar macrophages are recognized as a major contributing cell to the lung inflammatory processes. In previous studie
Publikováno v:
Experimental Lung Research. 18:173-190
The contribution of the type II pneumocyte to the pathogenesis of silicosis is largely unknown. Prominent features of silicosis are hyperplasia and hypertrophy of type II epithelial cells, often accompanied by phospholipid accumulation in the lung. T
Publikováno v:
Journal of leukocyte biology. 53(3)
This study addresses the hypothesis that silica- activated alveolar macrophages could release soluble fac- tors stimulating type II cell proliferation. Macrophages from control sheep were exposed or not in vitro to silica� aluminum-treated silica (
Publikováno v:
Experimental lung research. 18(5)
The type II pneumocyte changes in silicosis are characterized by hyperplasic and hypertrophic epithelial cells, and increased surfactant phospholipids in the bronchoalveolar lavage fluids (BALF). To assess the proliferative activity of alveolar linin