Zobrazeno 1 - 10
of 3 901
pro vyhledávání: '"Asano, A."'
Autor:
Yosuke Yamawaki, Hiroki So, Kana Oue, Satoshi Asano, Hisako Furusho, Mutsumi Miyauchi, Kotaro Tanimoto, Takashi Kanematsu
Publikováno v:
Biochemical and Biophysical Research Communications. 634:92-99
Porphyromonas gingivalis (P. gingivalis) is a Gram-negative anaerobe involved in the pathogenesis of chronic periodontitis, including local inflammation of the oral cavity. However, periodontal disease has recently been identified as a significant fa
Autor:
Kei Tamura, Kumiko Ishigaki, Orie Yoshida, Kazuyuki Terai, Keigo Iizuka, Naoki Sakurai, Tatsuya Heishima, Kazushi Asano
Publikováno v:
Research in Veterinary Science. 152:640-646
Hypoglycaemia caused by malignant tumours other than insulinoma is referred to as non-islet cell tumour hypoglycaemia (NICTH), which may be caused by hepatocellular carcinoma (HCC) and leiomyosarcoma (LMS) in veterinary medicine. However, the pathoge
Publikováno v:
Philosophical transactions of the Royal Society of London. Series B, Biological sciences. 377(1855)
Copy number variation (CNV) can cause phenotypic changes. However, in contrast to amino acid substitutions and cis -regulatory changes, little is known about the functional categories of genes in which CNV is important for adaptation to novel environ
Autor:
Takeshi Ike, Shigehiro Doi, Ayumu Nakashima, Kensuke Sasaki, Naoki Ishiuchi, Tomoichiro Asano, Takao Masaki
Publikováno v:
American Journal of Physiology-Renal Physiology. 323:F539-F552
The transcription factors hypoxia-inducible factor-1α and -2α (HIF-1α/2α) are the major regulators of the cellular response to hypoxia and play a key role in renal fibrosis associated with acute and chronic kidney disease. Jumonji domain-containi
Autor:
Masaki Saito, Hiroyuki Suzuki, Teizo Asano, Tomohiro Tanaka, Takeo Yoshikawa, Mika K. Kaneko, Yukinari Kato
Publikováno v:
Monoclonal Antibodies in Immunodiagnosis and Immunotherapy. 41:279-284
Immune checkpoint molecules have received attention as targets of cancer immunotherapy. Killer cell lectin-like receptor subfamily G member 1 (KLRG1) is one of the immune checkpoint molecules expressed in CD4
Autor:
Tomohiro Tokutake, Takashi Asano, Hajime Miyanishi, Shigetoshi Nakaya, Naotaka Izuo, Atsumi Nitta
Publikováno v:
Neurochemical Research. 47:2899-2908
The number of cannabis users is increasing in the world. However, the mechanisms involved in the psychiatric effects and addiction formation remain unclear. Medical treatments against cannabis addiction have not yet been established. Δ9-Tetrahydroca
Autor:
Kei Tamura, Kumiko Ishigaki, Orie Yoshida, Terai Kazuyuki, Naoki Sakurai, Tatsuya Heishima, Tomoko Fujiyuki, Chieko Kai, Kazushi Asano
Publikováno v:
Veterinary Medicine and Science. 8:1922-1929
Canine primary lung adenocarcinoma (CPLA) is suspected by radiography or computed tomography; however, since there are no tumour markers, early diagnosis is difficult, and the prognosis is poor due to increased tumour volume. Nectin-4 has been report
Autor:
Yuki Nishimura, Misaki Iwashita, Masato Hayashi, Takanori Shinjo, Yukari Watanabe, Tatsuro Zeze, Akiko Yamashita, Takao Fukuda, Terukazu Sanui, Tomomi Sano, Tomoichiro Asano, Fusanori Nishimura
Publikováno v:
Acta Diabetologica. 59:1275-1286
Aims Pancreatic β-cell apoptosis may be involved in the onset and progression of type 2 diabetes mellitus, although its mechanism remains unclear. We previously demonstrated that macrophage-derived interferon (IFN) β induced X-linked inhibitor of a
Autor:
Lauriane Sedes, Elisa Wondimu, Brittany Crockett, Jens Hansen, Anna Cantalupo, Keiichi Asano, Ravi Iyengar, Daniel B Rifkin, Silvia Smaldone, Francesco Ramirez
Publikováno v:
Hum Mol Genet
A disproportionate tall stature is the most evident manifestation in Marfan syndrome (MFS), a multisystem condition caused by mutations in the extracellular protein and TGFβ modulator, fibrillin-1. Unlike cardiovascular manifestations, there has bee
Autor:
Guanjie Li, Hiroyuki Suzuki, Junko Takei, Teizo Asano, Masato Sano, Tomohiro Tanaka, Hiroyuki Harada, Takuya Mizuno, Tomokazu Ohishi, Manabu Kawada, Mika K. Kaneko, Yukinari Kato
Publikováno v:
Monoclonal Antibodies in Immunodiagnosis and Immunotherapy. 41:53-58
The epidermal growth factor receptor (EGFR) contributes to tumor malignancy through gene amplification and/or protein overexpression. In our previous study, we developed an anti-human EGFR (hEGFR) monoclonal antibody (mAb), clone EMab-134 (mouse IgG