Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Anthony Possemato"'
Autor:
Mohammad J. Eslamizade, Albert Quintana, Elisenda Sanz, Karim Nader, Anthony Possemato, Matthew P. Stokes, Pavel V. Baranov, Randal J. Kaufman, Adonis Yiannakas, Maya Lalzar, Kathryn Abell, Vinh Tai Truong, Abdessattar Khlaifia, Mauro Costa-Mattioli, Shunit Gal-Ben-Ari, Arkady Khoutorsky, Azam Asgarihafshejani, Noah Cohen, Rapita Sood, Nahum Sonenberg, Vijendra Sharma, Peng Wang, Jean-Claude Lacaille, Alissa J. Nelson, Tzu-Yu Hung, Stephen J Kiniry, Fatemeh Saffarzadeh, A. Claudio Cuello, Danning Lou, Kobi Rosenblum
Publikováno v:
Signal Transduction and Targeted Therapy
An important tenet of learning and memory is the notion of a molecular switch that promotes the formation of long-term memory1–4. The regulation of proteostasis is a critical and rate-limiting step in the consolidation of new memories5–10. One of
Autor:
Sean A. Beausoleil, Michael Milhollen, Stephen J. Blakemore, Anthony Possemato, Claudia M. Espitia, Pete Smith, Michael P. Thomas, Allison Berger, Steffan T. Nawrocki, Kevin R. Kelly, Jennifer S. Carew
Publikováno v:
Clinical Cancer Research. 19:3577-3590
Purpose: Ovarian cancer has the highest mortality rate of all female reproductive malignancies. Drug resistance is a major cause of treatment failure and novel therapeutic strategies are urgently needed. MLN4924 is a NEDDylation inhibitor currently u
Autor:
Matthew H. Brush, Huihong You, Douglas N. Runckel, Joseph E. Aslan, Robert T. Youker, Laurel Thomas, Robert L. Milewski, Arndt Vogel, Jessica Endig, Hongjun Shu, Gary Thomas, Danielle M. Williamson, Haian Fu, Kam Sprott, Kenneth D. Greis, Yuhong Du, Anthony Possemato
Publikováno v:
Molecular Cell. 34:497-509
TRAIL selectively kills diseased cells in vivo, spurring interest in this death ligand as a potential therapeutic. However, many cancer cells are resistant to TRAIL, suggesting the mechanism mediating TRAIL-induced apoptosis is complex. Here we ident
Autor:
Roberto D. Polakiewicz, Peng Zhang, Zhenghe Wang, Chao Wang, Anthony Possemato, Ailan Guo, Cathleen R. Carlin, Sanford D. Markowitz, Lydia Beard
Publikováno v:
Oncogene
Protein tyrosine phosphatase nonreceptor type 14 (PTPN14) is frequently mutated in a variety of human cancers. However, the cell signaling pathways regulated by PTPN14 largely remain to be elucidated. Here, we identify a list of potential substrates