Zobrazeno 1 - 10
of 223 646
pro vyhledávání: '"medicine"'
Autor:
Lawrence R. Robinson
Publikováno v:
Europe PubMed Central
Publisher Summary This chapter discusses the epidemiology and classification of traumatic peripheral nerve injuries, the effects of these injuries on nerve and muscle, and how electrodiagnosis is used to help classify the injury. Traumatic injury to
Publikováno v:
Mucosal Immunology
Mucosal Immunology, 2022, 15 (2), pp.198--210. ⟨10.1038/s41385-021-00464-w⟩
Mucosal Immunology, 2022, 15 (2), pp.198--210. ⟨10.1038/s41385-021-00464-w⟩
As the COVID-19 pandemic is still ongoing, and considering the lack of efficacy of antiviral strategies to this date, and the reactive hyperinflammation leading to tissue lesions and pneumonia, effective treatments targeting the dysregulated immune r
Publikováno v:
Journal of Hypertension. 40:765-775
Angiotensin (Ang) II and elevated blood pressure are considered to be the main risk factors for atrial fibrillation. However, the proteome profiles and key mediators/signaling pathways involved in the development of Ang II-induced atrial fibrillation
Autor:
Evgeniy L, Gagarinskiy, Aleksey S, Averin, Viktor K, Uteshev, Pavel V, Sherbakov, Vladimir I, Telpuhov, Nikolay E, Shvirst, Yulya A, Karpova, Artem E, Gurin, Aleksandr V, Varlachev, Anatoliy L, Kovtun, Eugeny E, Fesenko
Publikováno v:
Annals of Cardiac Anaesthesia, Vol 25, Iss 1, Pp 41-47 (2022)
Background: It is well known that body temperature maintenance between 20 and 35°C prevents hypoxic damage. However, data regarding the ideal duration and permissible temperature boundaries for ultra-deep hypothermia below 20°C are rather fragmenta
Autor:
Daniel E. Rivera, Núria M. Pastor-Soler, Pei-Yin Ho, Valeria Mancino, Jessica Pham, Hui Li, Biagio Saitta, Kenneth R. Hallows
Publikováno v:
American Journal of Physiology-Renal Physiology. 322:F27-F41
Metformin treatment improved ADPKD disease severity in a relevant, slowly progressive ADPKD mouse model that recapitulates a PKD-associated PKD1 mutation. Relative to controls, metformin reduced kidney weight/body weight, cystic index and BUN levels,
Publikováno v:
Journal of Cardiovascular Pharmacology. 79:e41-e49
Treatment with trastuzumab, an antihuman epidermal growth factor receptor type 2 humanized monoclonal antibody, has been associated with heart failure in certain patients with cancer; however, the mechanism underlying trastuzumab-induced cardiac dysf
Autor:
Amanda L. Amin, Mark Redick, E. Shelley Hwang, Mingchu Xu, Jeffrey Thompson, Allison Aripoli, Emily Wedlock, Ashley I. Huppe, Haleigh E. Harper, Fang Fan, Yan Hong, Hana Razek, R Meierotto, Onalisa Winblad, Alastair M. Thompson, Susan G. Hilsenbeck, Ossama Tawfik, Christa R. Balanoff, Michael Ricci, Darlene Limback, Hayley Hansford, Kelsey E. Larson, Jamie L. Wagner, Lisa May, Fariba Behbod, Lawrence R. Ricci, Therese Cusick, Andy Futreal, Hanan S. Elsarraj, Carolyn S Kaufman, Marc Inciardi, Jianhua Zhang, Jason Gatewood, Andrew K. Godwin, Haley Haines, Rashna Madan
Publikováno v:
The Journal of Pathology. 256:186-201
Due to widespread adoption of screening mammography, there has been a significant increase in new diagnoses of ductal carcinoma in situ (DCIS). However, DCIS prognosis remains unclear. To address this gap, we developed an in vivo model, Mouse-INtraDu
Autor:
Dehong Mao, Weichun Li, Linglong Li, Xiaoying Fang, Zhongmei He, Feng Zhang, Wei Xuan, Jiao Deng
Publikováno v:
Bioengineered
article-version (VoR) Version of Record
Bioengineered, Vol 12, Iss 2, Pp 11823-11836 (2021)
article-version (VoR) Version of Record
Bioengineered, Vol 12, Iss 2, Pp 11823-11836 (2021)
Brain-derived neurotrophic factor (BDNF) regulates neuronal plasticity by targeting the tyrosine kinase B receptor (TrkB) receptor, but limited researches concentrate on the role of BDNF/TrkB signaling in vestibular compensation. In this study, rats
Autor:
Keishoku Sakuraba, Naoko Kaga, Ryuzo Kawamori, Yoshifumi Tamura, Noriko Ueno, Shin-ichi Ikeda, Hirotaka Watada, Hikari Taka, Saori Kakehi, Atsushi Kubota, Tetsuya Shiuchi
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 321:E766-E781
Physical inactivity impairs muscle insulin sensitivity. However, its mechanism is unclear. To model physical inactivity, we applied 24-h hind-limb cast immobilization (HCI) to mice with normal or high-fat diet (HFD) and evaluated intramyocellular lip
Autor:
Teresa C. Delgado, Jordi Gracia-Sancho, R. Garcia-Martinez, Erica Lafoz, Eduard Guasch, Genís Campreciós, Glòria Garrabou, María L. Martínez-Chantar, Virginia Hernández-Gea, Héctor García-Calderó, Juan Carlos García-Pagán, Maria Ruart, Aina Anton, Marina Vilaseca
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 321:G603-G616
We have developed two advanced cirrhosis regression experimental models with persistent relevant fibrosis and portal hypertension and an associated deteriorated metabolism that mimic what happens in patients. LI, despite improving metabolism, did not