Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Michael P. Meers"'
Autor:
Nicholas A Vitanza, Jay F. Sarthy, Christina M. Lockwood, Steven Henikoff, Patrick J. Paddison, Michael P. Meers, James M. Olson, Kami Ahmad, Heather Feldman, Derek H. Janssens, Jorja G. Henikoff
Publikováno v:
eLife
eLife, Vol 9 (2020)
eLife, Vol 9 (2020)
Lysine 27-to-methionine (K27M) mutations in the H3.1 or H3.3 histone genes are characteristic of pediatric diffuse midline gliomas (DMGs). These oncohistone mutations dominantly inhibit histone H3K27 trimethylation and silencing, but it is unknown ho
Autor:
Heather L. Mulder, Peter Vogel, Steven Henikoff, Marcin Kamiński, Richard K. Wilson, Jinghui Zhang, Anang A. Shelat, James R. Downing, Marc Valentine, Yanling Liu, Xin Zhou, Yiping Fan, Armita Bahrami, Arlene Naranjo, Collin Van Ryn, Rani E. George, Sara M. Federico, Beisi Xu, Jongrye Jeon, Seungjae Lee, Xiang Chen, Elizabeth Stewart, John Easton, Donald Yergeau, Shondra M. Pruett-Miller, Jay F. Sarthy, Michael P. Meers, Maged Zeineldin, Michael A. Dyer, Lyra Griffiths, Michael R. Clay, Jackie L. Norrie, Elaine R. Mardis, Rosa Nguyen, Alberto S. Pappo, Michael D. Hogarty, Jianrong Wu
Publikováno v:
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-20 (2020)
Nature Communications, Vol 11, Iss 1, Pp 1-20 (2020)
Aggressive cancers often have activating mutations in growth-controlling oncogenes and inactivating mutations in tumor-suppressor genes. In neuroblastoma, amplification of the MYCN oncogene and inactivation of the ATRX tumor-suppressor gene correlate
Autor:
A. Gregory Matera, Michael P. Meers, Karen Adelman, Robert J. Duronio, Daniel J. McKay, Brian D. Strahl, Christopher A. Lavender, Telmo Henriques
Publikováno v:
eLife
eLife, Vol 6 (2017)
eLife, Vol 6 (2017)
Histone H3 lysine 36 methylation (H3K36me) is thought to participate in a host of co-transcriptional regulatory events. To study the function of this residue independent from the enzymes that modify it, we used a ‘histone replacement’ system in D