Zobrazeno 91 - 100
of 884
pro vyhledávání: '"Ochi A"'
Publikováno v:
Biochemical and Biophysical Research Communications. 466:289-294
AMP-activated protein kinase (AMPK) has been shown to regulate protein metabolism in skeletal muscle. We previously found that levels of Forkhead box proteins, FoxO1 and FoxO3a, and myostatin in rat gastrocnemius increased after exercise-induced musc
Autor:
Akiko Sato, Mitsune Tanimoto, Toshio Kubo, Takehiro Tanaka, Yuka Kato, Katsuyuki Hotta, Kenichiro Kudo, Daisuke Minami, Katsuyuki Kiura, Nagio Takigawa, Daijiro Harada, Masahiro Tabata, Hideko Isozaki, Nobuaki Ochi, Masanori Fujii, Shinsuke Hashida, Kadoaki Ohashi, Shinichi Toyooka
Publikováno v:
Cancer Science
Malignant mesothelioma is an aggressive and therapy-resistant neoplasm arising from mesothelial cells. Evidence suggests that the major pathology associated with asbestos-induced mesothelioma is local iron overload. In the present study, we induced i
Autor:
Sakiko Kitamura, Naoki Abe, Shinichiro Ochi, Hajime Yano, Keizo Ikemune, Toshihiro Yorozuya, Mohammed E. Choudhury, Tasuku Nishihara, Yuki Nishikawa, Junya Tanaka, Keisuke Sekiya, Taisuke Hamada
Publikováno v:
Neurochemistry International. 134:104672
Chronic constriction injury of the sciatic nerve is frequently considered as a cause of chronic neuropathic pain. Marked activation of microglia in the posterior horn (PH) has been well established with regard to this pain. However, microglial activa
Autor:
Itabajara da Silva Vaz, Shiro Murata, Shuji Ando, Kazuhiko Ohashi, Naftaly Githaka, Yamato Sajiki, Akie Ochi, Carlos Logullo, Satoru Konnai, Shinji Yamada, Takuya Ito, Tomohiro Okagawa, Hiroki Kawabata, Naoya Maekawa, Masayoshi Isezaki
Publikováno v:
Ticks and Tick-borne Diseases. 11:101332
Tick saliva contains immunosuppressants which are important to obtain a blood meal and enhance the infectivity of tick-borne pathogens. In Japan, Ixodes persulcatus is a major vector for Lyme borreliosis pathogens, such as Borrelia garinii, as well a
Autor:
Masato Yuasa, Toshitaka Yoshii, Takashi Hirai, Yutaka Kobayashi, Hoashi Numata, Hiroyuki Inose, Mieradili Mulati, Takahashi Akira, Shingo Sato, Yoichi Ezura, Yuichi Hiraoka, Hiroki Ochi, Masanori Saito, Atsushi Okawa
Publikováno v:
Bone. 130:115076
In the past decade, a growing importance has been placed on understanding the significance of long noncoding RNAs (lncRNAs) in regulating development, metabolism, and homeostasis. Osteoblast proliferation and differentiation are essential elements in
Autor:
Satoshi Fujisawa, Motoshi Komatsubara, Fumio Otsuka, Naoko Tsukamoto-Yamauchi, Jun Wada, Kanako Ogura-Ochi, Kishio Toma, Kenichi Inagaki
Publikováno v:
Peptides. 113
The impact of orexins on anterior pituitary function has yet to be clarified. We studied the effects of orexin A and its interaction with the bone morphogenetic protein (BMP) system on the regulatory role of prolactin synthesis using rat lactotrope G
Autor:
Philipp Kaldis, Masanori Saito, Takahashi Akira, Shingo Sato, Hiroki Ochi, Atsushi Okawa, Yutaka Kobayashi, Hiroyuki Inose, Mieradili Mulati, Hoashi Numata
Publikováno v:
The Journal of biological chemistry. 293(50)
Bone mass is maintained by a balance between osteoblast-mediated bone formation and osteoclast-mediated bone resorption. Although recent genetic studies have uncovered various mechanisms that regulate osteoblast differentiation, the molecular basis o
Autor:
Kiyohiro Yamazaki, Yoko Mori, Yuki Ozaki, Shinichiro Ochi, Shunsuke Nakata, Mitsuo Okita, Jun-ichi Iga, Shu-ichi Ueno, Kentaro Kawabe, Yuta Yoshino
Publikováno v:
Psychiatry research. 272
Objectives Ghrelin regulates appetite and also plays important roles in cognition and may be involved in vulnerability to SCZ. Methods In this study, we measured mRNA expression of the ghrelin-related molecules, growth hormone secretagogue receptor 1
Autor:
Hideharu Abe, Hiroyuki Ono, Tatsuya Tominaga, Masanori Tamaki, Seiji Kishi, Arisa Ochi, Kojiro Nagai, Toshio Doi, Taichi Murakami, Masayuki Kohashi, Akiko Sakurai
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-14 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-14 (2018)
Diabetic nephropathy (DN) is the major cause of end-stage renal failure and is associated with increased morbidity and mortality compared with other causes of renal diseases. We previously found that Smad1 plays a critical role in the development of
Autor:
Grace Naswa Makokha, Yizhou Zhang, Kanma Shiraishi, Hiroshi Aikata, Takashi Fujita, Michio Imamura, Daiki Miki, Nobuhiko Hiraga, Yoshiiku Kawakami, Takuro Uchida, Takashi Nakahara, Eisuke Murakami, C. Nelson Hayes, Kazuaki Chayama, Yu Izaki, Motonobu Nomura, Naoya Oka, Tomokazu Kawaoka, Masataka Tsuge, Hiromi Abe-Chayama, Mio Kurihara, Ken Tsushima, Misa Yamashita, Hidenori Ochi, Ojiro Sato
Publikováno v:
Virology. 525
The events in the immune response to hepatitis B virus (HBV) remain unclear. We analyzed the direct influence of HBV on gene expression in human hepatocytes under immunodeficient conditions using a human hepatocyte chimeric mouse model. HBV-infected