Zobrazeno 1 - 10
of 274
pro vyhledávání: '"Ochi A"'
Publikováno v:
Neuroscience Research. 165:45-50
Chronic fatigue syndrome (CFS) is characterized by long-lasting fatigue, and a range of symptoms, and is involved in homeostasis disruption. CFS patients frequently complain of low grade fever or chill even under normal body temperature indicating th
Autor:
Danxi Li, Yasuyoshi Watanabe, Yuta Ochi, Mika Shigeta, Yilong Cui, Di Hu, Takashi Okauchi, Hiroyuki Neyama, Shigeru Kabayama
Publikováno v:
Biochemical and Biophysical Research Communications. 535:1-5
Reactive oxygen species (ROS) are highly reactive and directly attack surrounding biomolecules to deteriorate cellular and tissue functions. Meanwhile, ROS also serve as signaling mediators to upregulate pro-inflammatory cytokine expression via activ
Autor:
Hisao Nishijo, Susumu Urakawa, Takaya Oshima, Son Tien Nguyen, Naoto Fujita, Natsuki Goto, Kaho Takaishi, Ryosuke Ochi
Publikováno v:
PLoS ONE, Vol 16, Iss 9, p e0256655 (2021)
PLoS ONE
PLoS ONE
Metabolic disorders are associated with a higher risk of psychiatric disorders. We previously reported that 20-week-old Otsuka Long-Evans Tokushima fatty (OLETF) rats, a model of progressive type 2 diabetes, showed increased anxiety-like behavior and
Autor:
Hiroshi Kumon, Naoki Abe, Jun-ichi Iga, Shuken Boku, Keisuke Sekiya, Shu-ichi Ueno, Tasuku Nishihara, Yuta Yoshino, Yu Funahashi, Shinichiro Ochi
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
The pathophysiology of delayed carbon monoxide (CO) encephalopathy remains unclear. In this study, the effects of CO exposure on the dentate gyrus (DG) were investigated in a Wistar rat model by histochemical and molecular methods. Model rats showed
Autor:
Wataru Nino, Natsuki Goto, Hisao Nishijo, Kazuyoshi Hisatsune, Ryosuke Ochi, Susumu Urakawa, Naoto Fujita
Publikováno v:
Biomedical research (Tokyo, Japan). 41(1)
Mild hyperbaric treatment prevents type 2 diabetes progression due to increased oxygen concentration and blood flow in skeletal muscle. However, it remains unknown whether this treatment is effective during all stages of type 2 diabetes. This study a
Autor:
Toshiko Tanaka-Kagawa, Sadayuki Ochi, Susumu Ohkawara, Hideto Jinno, Nobumitsu Hanioka, Takashi Isobe
Publikováno v:
Food and Chemical Toxicology. 111:417-422
Naringenin, a flavanone found in citrus fruits, is mainly metabolized into glucuronide(s) by UDP-glucuronosyltransferase (UGT) enzymes in mammals. In the present study, the glucuronidation of naringenin in the liver and intestine microsomes of humans
Autor:
Jun-ichi Iga, Shunsuke Nakata, Kiyohiro Yamazaki, Yuta Yoshino, Shinichiro Ochi, Shu-ichi Ueno
Publikováno v:
Psychopharmacology. 234:1663-1669
Nitric oxide (NO) is a neurotransmitter that may be related to major depressive disorder (MDD) because the selective neuronal NO synthase (NOS) inhibitor, 7-nitroindazole, induces a dose-dependent antidepressant-like effect. NO modulates major neurot
Dehydroepiandrosterone (DHEA) is an adrenal steroid hormone, which has the highest serum concentration among steroid hormones with DHEA sulfate (DHEAS). DHEA possesses an inhibitory action on glucose-6-phosphate dehydrogenase (G6PD), the first pentos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d5f2115e6db649cb673dd53a3206c6c
https://europepmc.org/articles/PMC6336967/
https://europepmc.org/articles/PMC6336967/
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 310:H1118-H1128
Voltage-gated L-type Ca2+ current ( ICa,L) induces contraction of arterial smooth muscle cells (ASMCs), and ICa,L is increased by H2O2 in ASMCs. Superoxide released from the mitochondrial respiratory chain (MRC) is dismutated to H2O2. We studied whet
Autor:
Atsushi Kanda, Naofumi Hashimoto, Keisuke Kimura, Takaki Kawachi, Akitoshi Matsuda, Kayo Yuminoki, Masanori Ochi
Publikováno v:
AAPS PharmSciTech. 17:932-939
The aim of the present study was to develop amorphous solid dispersion (ASD) of meloxicam (MEL) for providing rapid onset of action. ASDs of MEL with polyvinylpyrrolidone (PVP) K-30 (MEL/PVP), HPC-SSL (MEL/HPC), and Eudragit EPO (MEL/EPO) were prepar