Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Mazzone, A."'
Autor:
Carmen Navarrete, Adela García-Martín, Alejandro Correa-Sáez, María E. Prados, Francisco Fernández, Rafael Pineda, Massimiliano Mazzone, Marina Álvarez-Benito, Marco A. Calzado, Eduardo Muñoz
Background Traumatic brain injury (TBI) is characterized by a primary mechanical injury and a secondary injury associated with neuroinflammation, blood–brain barrier (BBB) disruption and neurodegeneration. We have developed a novel cannabidiol amin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::757de5b8fcd0c93406060f81d1be628e
https://lirias.kuleuven.be/handle/20.500.12942/699756
https://lirias.kuleuven.be/handle/20.500.12942/699756
Autor:
Gaia Spinetti, Mario Tirone, Pasquale Creo, Simona Greco, Matteo Carrara, Paola Fuschi, Davide Maselli, Carlo Gaetano, Massimiliano Mazzone, Biagina Maimone, Fabio Martelli, Christine Voellenkle, Germana Zaccagnini, Marialucia Longo
Publikováno v:
Cell Death and Disease, Vol 12, Iss 5, Pp 1-14 (2021)
Cell Death & Disease
Cell Death & Disease
Hypoxia-induced miR-210 is a crucial component of the tissue response to ischemia, stimulating angiogenesis and improving tissue regeneration. Previous analysis of miR-210 impact on the transcriptome in a mouse model of hindlimb ischemia showed that
Autor:
Passelli, Katiuska, Prat-Luri, Borja, Merlot, Margot, Goris, Michiel, Mazzone, Massimiliano, Tacchini-Cottier, Fabienne
Publikováno v:
PLoS pathogens, vol. 18, no. 1, pp. e1010247
PLoS Pathogens, Vol 18, Iss 1, p e1010247 (2022)
PLoS Pathogens
PLoS Pathogens, Vol 18, Iss 1, p e1010247 (2022)
PLoS Pathogens
Neutrophils are the first line of defence against invading pathogens. Although neutrophils are well-known professional killers, some pathogens including Leishmania (L.) parasites survive in neutrophils, using these cells to establish infection. Manip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::6284bbb7c8f1745533ad7022b794f77d
https://lirias.kuleuven.be/handle/20.500.12942/689434
https://lirias.kuleuven.be/handle/20.500.12942/689434
Autor:
Arnaud Köhler, Roberta Mastrantonio, Ward Celus, Massimiliano Mazzone, Jens Serneels, Abhishek D. Garg, Sarah Trusso Cafarello, Luca Tamagnone, Jean-Christophe Marine, Oliver Bechter, Silvia Rivis, Ewout Landeloos, Yannick Van Herck, Ana Isabel Oliveira, Véronique Flamand, Mario Di Matteo, Heleen H. Van Acker, Bruno M. Costa
Publikováno v:
Cancer Immunol Res
Cytotoxic T cell (CTL) infiltration of the tumor carries the potential to limit cancer progression, but their exclusion by the immunosuppressive tumor microenvironment hampers the efficiency of immunotherapy. Here, we show that expression of the axon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::701ba4fbeca6ed220bab98e7978d02eb
https://europepmc.org/articles/PMC7612191/
https://europepmc.org/articles/PMC7612191/
Autor:
Germana Zaccagnini, Mario Tirone, Davide Maselli, Simona Greco, Paola Fuschi, Marialucia Longo, Christine Voellenkle, Carlo Gaetano, Fabio Martelli, Massimiliano Mazzone, Gaia Spinetti, Biagina Maimone, Matteo Carrara, Pasquale Creo
Publikováno v:
Cell Death & Disease
Cell Death and Disease, Vol 12, Iss 6, Pp 1-1 (2021)
Cell Death and Disease, Vol 12, Iss 6, Pp 1-1 (2021)
Hypoxia-induced miR-210 is a crucial component of the tissue response to ischemia, stimulating angiogenesis and improving tissue regeneration. Previous analysis of miR-210 impact on the transcriptome in a mouse model of hindlimb ischemia showed that
Autor:
Mate Kiss, Geert Raes, Maryse Schmoetten, Helena Van Damme, Andy Wullaert, Jiri Keirsse, Mohamed Lamkanfi, Yvon Elkrim, Pauline M. R. Bardet, Junbin Qian, Aleksandar Murgaski, Louis Boon, Diether Lambrechts, Samantha Pretto, Alain Beschin, Geert van Loo, Massimiliano Mazzone, Manuel Ehling, Jo A. Van Ginderachter, Damya Laoui, Sana M. Arnouk, Evangelia Bolli, Ayla Debraekeleer, Amelie Fossoul, Els Lebegge, Jan Brughmans, Lieselotte Vande Walle, Pedro Henrique Viana Saavedra
IL1β is a central mediator of inflammation. Secretion of IL1β typically requires proteolytic maturation by the inflammasome and formation of membrane pores by gasdermin D (GSDMD). Emerging evidence suggests an important role for IL1β in promoting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ecbd8e2b94bd021c47f81139d016a57
https://doi.org/10.1158/2326-6066.cir-20-0431
https://doi.org/10.1158/2326-6066.cir-20-0431
Autor:
Rosa Trotta, Anne Theres Henze, Francesca Orso, Jonas Van Audenaerde, Alberto Griffa, Mircea Ivan, Federica Cappellesso, Daniela Taverna, Greet Van den Berghe, Manuel A. Sanchez-Garcia, Fabio Martelli, Massimiliano Mazzone, Hans Prenen, Cyril Corbet, Federico Virga, Olivier Feron, Carla Riera-Domingo, Evelien Smits, Benoit Stijlemans, Bart Ghesquière, Jo A. Van Ginderachter, Lies Langouche, Cristina Ivan, Claude Libert, Ananda S. Mirchandani, Jolien Vandewalle, Damya Laoui, Sarah R. Walmsley
Publikováno v:
SCIENCE ADVANCES
Science Advances, Vol. 7, no.19, p. eabf0466 (2021)
Science Advances
Virga, F, Cappellesso, F, Stijlemans, B, Henze, A-T, Trotta, R, Van Audenaerde, J, Mirchandani, A S, Sanchez Garcia, M A, Vandewalle, J, Orso, F, Riera-Domingo, C, Griffa, A, Ivan, C, Smits, E, Laoui, D, Martelli, F, Langouche, L, Van den Berghe, G, Feron, O, Ghesquiere, B, Prenen, H, Libert, C, Walmsley, S R, Corbet, C, Van Ginderachter, J A, Ivan, M, Taverna, D & Mazzone, M 2021, ' Macrophage miR-210 induction and metabolic reprogramming in response to pathogen interaction boost life-threatening inflammation ', Science Advances . https://doi.org/10.1126/sciadv.abf0466
Science Advances, Vol. 7, no.19, p. eabf0466 (2021)
Science Advances
Virga, F, Cappellesso, F, Stijlemans, B, Henze, A-T, Trotta, R, Van Audenaerde, J, Mirchandani, A S, Sanchez Garcia, M A, Vandewalle, J, Orso, F, Riera-Domingo, C, Griffa, A, Ivan, C, Smits, E, Laoui, D, Martelli, F, Langouche, L, Van den Berghe, G, Feron, O, Ghesquiere, B, Prenen, H, Libert, C, Walmsley, S R, Corbet, C, Van Ginderachter, J A, Ivan, M, Taverna, D & Mazzone, M 2021, ' Macrophage miR-210 induction and metabolic reprogramming in response to pathogen interaction boost life-threatening inflammation ', Science Advances . https://doi.org/10.1126/sciadv.abf0466
Unbalanced immune responses to pathogens can be life-threatening although the underlying regulatory mechanisms remain unknown. Here, we show a hypoxia-inducible factor 1α-dependent microRNA (miR)-210 up-regulation in monocytes and macrophages upon p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9634cff2574f34dbf7ed4c143a89b96d
http://hdl.handle.net/2318/1827106
http://hdl.handle.net/2318/1827106
Autor:
Mario Di Matteo, Elisa Meroni, Marc Ferrante, Veronica De Simone, Michelle Stakenborg, Bram Verstockt, Severine Vermeire, Sare Verstockt, Gera Goverse, Massimiliano Mazzone, Eduardo J. Villablanca, Gianluca Matteoli, Guy E. Boeckxstaens, Paulo Czarnewski
Background and Aims Ulcerative colitis [UC] is associated with excessive neutrophil infiltration and collateral tissue damage, but the link is not yet completely understood. Since c-MET receptor tyrosine kinase [MET] is required for neutrophil chemoa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3fdb319338c915fedc56dbfcff3aaf3
https://lirias.kuleuven.be/handle/123456789/656521
https://lirias.kuleuven.be/handle/123456789/656521
Autor:
Albert Y Zhang, Aung Aung Kywe Moe, Matthew W. Trewella, Stuart B. Mazzone, Kirsty R. Short, Isaac N. Edwards, Matthew E. Ritchie, Brendon Y. Chua, Conor J. Bloxham, Helle Bielefeldt-Ohmann, Charity W. Law, Keng Yih Chew, Alice E McGovern, Nathalie A. J. Verzele, Katina D. Hulme, Oliver Wightman
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental BiologyREFERENCES. 35(3)
Influenza A virus (IAV) is rapidly detected in the airways by the immune system, with resident parenchymal cells and leukocytes orchestrating viral sensing and the induction of antiviral inflammatory responses. The airways are innervated by heterogen
Autor:
Choon Boon Sim, Peter D. Sly, Ashik Ullah, Vivian Zhang, John W. Upham, Kirsten Spann, Al Amin Sikder, Maria B. Sukkar, Stuart B. Mazzone, Jennifer Simpson, Wan Jun Gan, Simon Phipps, Jason P. Lynch, Enzo R. Porrello, Raymond J. Steptoe, K. Lane, Rhiannon B. Werder, Zhixuan Loh
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 16, Iss 7, p e1008651 (2020)
PLoS Pathogens, Vol 16, Iss 7, p e1008651 (2020)
Type-2 immunity elicits tissue repair and homeostasis, however dysregulated type-2 responses cause aberrant tissue remodelling, as observed in asthma. Severe respiratory viral infections in infancy predispose to later asthma, however, the processes t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a1bb7086241df99cf129933389383c0
https://hdl.handle.net/10453/142862
https://hdl.handle.net/10453/142862