Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Kroemer G"'
Autor:
Ja, Gonzalo, González-García A, ELENA BAIXERAS, Zamzami N, Tarazona R, Rappuoli R, Martínez C, Kroemer G, Terezone R
Publikováno v:
Europe PubMed Central
Intravenous injection of a bacterial superantigen such as Staphylococcus aureus enterotoxin B (SEB) causes transient activation and expansion of SEB-reactive V beta 8+ T cells, as well as specific down-regulation of the immune response, through parti
Autor:
Hirsch, T., Dallaporta, B., Zamzami, N., Santos A. Susin, Ravagnan, L., Marzo, I., Brenner, C., Kroemer, G.
Publikováno v:
Scopus-Elsevier
Proteasomes and mitochondrial membrane changes are involved in thymocyte apoptosis. The hierarchical relationship between protease activation and mitochondrial alterations has been elusive. Here we show that inhibition of proteasomes by two specific
Autor:
Gonzalo, J. A., Baixeras, E., Ana Gonzalez-Garcia, George-Chandy, A., Rooijen, N., Martínez-A, C., Kroemer, G.
Publikováno v:
Europe PubMed Central
Scopus-Elsevier
Scopus-Elsevier
Superantigens have multiple pleiotropic effects in vivo, causing the activation, proliferation, and deletion of specific T cells. In our study, we analyzed the effects of the bacterial superantigen Staphylococcus aureus enterotoxin B (SEB) on periphe
Publikováno v:
International archives of allergy and immunology. 97(4)
High doses of recombinant interleukin-2 (IL-2) may induce autoimmune lesions in patients receiving experimental cancer treatment. In most cases, the manifestation of autoaggression is transient and organ-specific, predominantly affecting the thyroid
Autor:
Dallaporta, B., Hirsch, T., Susin, S. A., Zamzami, N., Larochette, N., Brenner, C., Isabel Marzo, Kroemer, G.
Publikováno v:
Scopus-Elsevier
Europe PubMed Central
Europe PubMed Central
The subcellular compartmentalization of ions is perturbed during the process of apoptosis. In this work, we investigated the impact of K+ on the apoptotic process in thymocytes and T cell hybridoma cells. Irrespective of the death-inducing stimulus (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a961565d91e07b7cfaf99560699b8eb
http://www.scopus.com/inward/record.url?eid=2-s2.0-0032103970&partnerID=MN8TOARS
http://www.scopus.com/inward/record.url?eid=2-s2.0-0032103970&partnerID=MN8TOARS
Autor:
Dallaporta, B., Philippe MARCHETTI, Pablo, M. A., Maisse, C., Duc, H. -T, Métivier, D., Zamzami, N., Geuskens, M., Kroemer, G.
Publikováno v:
HAL
ResearcherID
Journal of Immunology
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 1999, 162 (11), pp.6534-6542
Scopus-Elsevier
ResearcherID
Journal of Immunology
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 1999, 162 (11), pp.6534-6542
Scopus-Elsevier
Apoptosis is accompanied by major changes in ion compartmentalization and transmembrane potentials. Thymocyte apoptosis is characterized by an early dissipation of the mitochondrial transmembrane potential, with transient mitochondrial swelling and a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02d8dc95b6c6d5fa66628e1842aa52d9
https://hal.archives-ouvertes.fr/hal-01600967
https://hal.archives-ouvertes.fr/hal-01600967
Autor:
Frank Bellivier, Christine Passerieux, Julien Dubreucq, Isabelle Martins, Antoine Lafarge, Pierre-Michel Llorca, Delphine Capdevielle, Ludovic Samalin, Caroline Dubertret, Franck Oury, Valentina Sica, Stéphanie Moriceau, Fabrice Berna, Raymond Schwan, Guido Kroemer, Face-Sz, Christophe Magnan, Sébastien Gard, José Manuel Bravo-San Pedro, Marion Leboyer, Paul Roux, Bruno Etain, Emilie Olié, Jasmina Mallet, David Misdrahi, Raoul Belzeaux, Maria Chiara Maiuri, Adrien Joseph, Jonathan Pol, Philippe Courtet, Guillaume Fond, Franck Schürhoff, D' Amato Thierry, Joséphine Loftus, Gerasimos Anagnostopoulos, Mircea Polosan
Publikováno v:
Cell Death and Disease
Cell Death and Disease, Nature Publishing Group, 2020, 11 (7), pp.502. ⟨10.1038/s41419-020-2716-5⟩
Cell Death and Disease, Vol 11, Iss 7, Pp 1-10 (2020)
Cell Death & Disease
Cell Death and Disease, 2020, 11 (7), pp.502. ⟨10.1038/s41419-020-2716-5⟩
Cell Death and Disease, Nature Publishing Group, 2020, 11 (7), pp.502. ⟨10.1038/s41419-020-2716-5⟩
Cell Death and Disease, Vol 11, Iss 7, Pp 1-10 (2020)
Cell Death & Disease
Cell Death and Disease, 2020, 11 (7), pp.502. ⟨10.1038/s41419-020-2716-5⟩
Acyl coenzyme A binding protein (ACBP), also known as diazepam binding inhibitor (DBI) is a multifunctional protein with an intracellular action (as ACBP), as well as with an extracellular role (as DBI). The plasma levels of soluble ACBP/DBI are elev
Autor:
Mara C. Spinella, Romina Monzani, Luigi Maiuri, Alessandro Luciani, Federica Rossin, Mauro Piacentini, Giorgia Renga, Christian Grimm, Guido Kroemer, Marco Silano, Valeria Raia, Enrico Garaci, Stefano Guido, Vasilis Oikonomou, Antonella Tosco, Valeria Rachela Villella, Andrea Venerando, Giorgio Cozza, Eleonora Ferrari, Speranza Esposito, Yu-Kai Chao, Luigina Romani
Publikováno v:
The EMBO Journal
Intestinal handling of dietary proteins usually prevents local inflammatory and immune responses and promotes oral tolerance. However, in ~ 1% of the world population, gluten proteins from wheat and related cereals trigger an HLA DQ2/8‐restricted T
Autor:
Lorenzo Galluzzi, Thomas Rudel, Hans-Uwe Simon, Vishva M. Dixit, Erwin F. Wagner, Marie-Lise Gougeon, Andreas Linkermann, J M Bravo-San Pedro, Rosario Rizzuto, Cecília M. P. Rodrigues, Gian Maria Fimia, Hidenori Ichijo, Mathieu J.M. Bertrand, Kodi S. Ravichandran, Francis Ka-Ming Chan, Stephen W.G. Tait, Jochen H. M. Prehn, Richard A. Lockshin, Valina L. Dawson, Andreas Villunger, Sharad Kumar, Emily H. Cheng, Carlos López-Otín, Theocharis Panaretakis, Lucia Altucci, Gabriel A. Rabinovich, Michelangelo Campanella, Peter Vandenabeele, Marcus E. Peter, Francesco Cecconi, Noboru Mizushima, Ilio Vitale, Frank Madeo, Mikhail V. Blagosklonny, Zahra Zakeri, Stuart A. Aaronson, Gabriel Núñez, Eric H. Baehrecke, Nektarios Tavernarakis, Gyorgy Szabadkai, Eleonora Candi, Brent R. Stockwell, Dale E. Bredesen, Seamus J. Martin, Thomas Kaufmann, Sonia Melino, Dieter Adam, John M. Abrams, Katiuscia Bianchi, Yufang Shi, Emad S. Alnemri, Klas Blomgren, Pascal Meier, Catherine Brenner, Michael O. Hengartner, Philipp J. Jost, J M Hardwick, Eileen White, T Vanden Berghe, N. Di Daniele, Nicolas G. Bazan, H. L. Tang, Mauro Piacentini, V De Laurenzi, Beth Levine, Margherita Annicchiarico-Petruzzelli, Josef M. Penninger, Walter Malorni, Ted M. Dawson, Carmen Garrido, David W. Andrews, Douglas R. Green, György Hajnóczky, Jerry E. Chipuk, Wafik S. El-Deiry, Christoph Borner, Stuart A. Lipton, John A. Cidlowski, Klaus-Michael Debatin, Junying Yuan, Jan Paul Medema, Bertrand Joseph, Aaron Ciechanover, Ute M. Moll, Hinrich Gronemeyer, Paolo Pinton, Gerry Melino, Daniel J. Klionsky, Simone Fulda, John J. Lemasters, Cristina Muñoz-Pinedo, Hamsa Puthalakath, Navdeep S. Chandel, R De Maria, Jean-Christophe Marine, Richard A. Flavell, Brian David Dynlacht, W. G. Wood, Henning Walczak, David C. Rubinsztein, Guido Kroemer, Oliver Kepp, Richard A. Knight, Andrew Oberst, Enrico Lugli, J-C Martinou, Boris Zhivotovsky, Yoshihide Tsujimoto
Publikováno v:
Cell death and differentiation
Cell Death and Differentiation
Kaufmann, Thomas; Simon, Hans-Uwe (2015). Essential versus accessory aspects of cell death: recommendations of the NCCD 2015. Cell death and differentiation, 22(1), pp. 58-73. Nature Publishing Group 10.1038/cdd.2014.137
CELL DEATH AND DIFFERENTIATION
Cell Death and Differentiation
Kaufmann, Thomas; Simon, Hans-Uwe (2015). Essential versus accessory aspects of cell death: recommendations of the NCCD 2015. Cell death and differentiation, 22(1), pp. 58-73. Nature Publishing Group 10.1038/cdd.2014.137
CELL DEATH AND DIFFERENTIATION
Cells exposed to extreme physicochemical or mechanical stimuli die in an uncontrollable manner, as a result of their immediate structural breakdown. Such an unavoidable variant of cellular demise is generally referred to as ?accidental cell death' (A
Autor:
Guido Kroemer, Massimo Pettoello-Mantovani, Marco Silano, Bob J. Scholte, Ilaria Russo, Stefano Guido, Valeria Raia, Antonella De Matteis, Valeria Rachela Villella, Manuela Gavina, Alessandro Luciani, Rosa Carnuccio, Luigi Maiuri, Maria Chiara Maiuri, Speranza Esposito, Alberto Luini
Publikováno v:
Autophagy 8 (2012): 1657–1672. doi:10.4161/auto.21483
info:cnr-pdr/source/autori:Luciani A, Villella VR, Esposito S, Gavina M, Russo I, Silano M, Guido S, Pettoello-Mantovani M, Carnuccio R, Scholte B, De Matteis MA, Maiuri MC, Raia V, Luini A, Kroemer G, Maiuri L/titolo:Targeting autophagy as a novel strategy for facilitating the therapeutic action of potentiators on Delta F508 cystic fibrosis transmembrane conductance regulator/doi:10.4161%2Fauto.21483/rivista:Autophagy/anno:2012/pagina_da:1657/pagina_a:1672/intervallo_pagine:1657–1672/volume:8
Autophagy, 8(11), 1657-1672. Landes Bioscience
info:cnr-pdr/source/autori:Luciani A, Villella VR, Esposito S, Gavina M, Russo I, Silano M, Guido S, Pettoello-Mantovani M, Carnuccio R, Scholte B, De Matteis MA, Maiuri MC, Raia V, Luini A, Kroemer G, Maiuri L/titolo:Targeting autophagy as a novel strategy for facilitating the therapeutic action of potentiators on Delta F508 cystic fibrosis transmembrane conductance regulator/doi:10.4161%2Fauto.21483/rivista:Autophagy/anno:2012/pagina_da:1657/pagina_a:1672/intervallo_pagine:1657–1672/volume:8
Autophagy, 8(11), 1657-1672. Landes Bioscience
Channel activators (potentiators) of cystic fibrosis (CF) transmembrane conductance regulator (CFTR), can be used for the treatment of the small subset of CF patients that carry plasma membrane-resident CFTR mutants. However, approximately 90% of CF