Zobrazeno 1 - 10
of 133
pro vyhledávání: '"Ochi A"'
Autor:
Norikazu Isoda, Manyando Simbotwe, Mai Tsujinouchi, Misheck Shawa, Hideaki Higashi, Akihiro Ochi, Tuvshinzaya Zorigt, Yoshikazu Furuta, Tomoko Shimizu, Jargalsaikhan Enkhtuya
Publikováno v:
PLoS ONE, Vol 16, Iss 10, p e0258317 (2021)
PLoS ONE
PLoS ONE
Anthrax is a zoonotic disease caused by the gram-positive spore-forming bacteriumBacillus anthracis. Detecting naturally acquired antibodies against anthrax sublethal exposure in animals is essential for anthrax surveillance and effective control mea
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 2, p e0247410 (2021)
PLoS ONE, Vol 16, Iss 2, p e0247410 (2021)
The aim of this study was to examine the effect of long-term locking plate fixation on the cortical bone of the canine radius. Locking compression plates were fixed to the left and right radius in dogs (n = 3). The left radius was fixed with a lockin
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Bone marrow (BM) chimeric mice are a valuable tool in the field of immunology, with the genetic manipulation of donor cells widely used to study gene function under physiological and pathological settings. To date, however, BM chimera protocols requi
Autor:
Tomofumi Miyamoto, Ayaka Ito, Akira Matsumoto, Kozue Ochi, Sho Yamasaki, Marie Saka-Tanaka, Makoto Suematsu, Kumiko Fujieda, Takayoshi Suganami, Seiichiro Aoe, Miyako Tanaka, Naotake Tsuboi, Yuki Sugiura, Yoshihiro Miyamoto, Hiro Kohda, Shoichi Maruyama, Taiki Miyazawa, Yoshihiro Ogawa
Publikováno v:
The Journal of Experimental Medicine
This study demonstrates that β-glucosylceramide in combination with free cholesterol acts on Mincle as an endogenous ligand to induce cell death–triggered sustained inflammation after renal ischemia–reperfusion injury.
Accumulating evidence
Accumulating evidence
Autor:
Toshiro Takai, Ko Okumura, Sakiko Shimura, Susumu Nakae, Hideoki Ogawa, Shigaku Ikeda, Izumi Nishioka, Natsuko Maruyama, Hideo Iida, Seiji Kamijo, Hirono Ochi
Publikováno v:
Journal of Investigative Dermatology. 137:1578-1582
Autor:
Hiromi Kan, Takuro Uchida, Hiromi Abe-Chayama, Chise Tateno, Hiroshi Aikata, Masataka Tsuge, Grace Naswa Makokha, Nobuhiko Hiraga, Hidenori Ochi, C. Nelson Hayes, Michio Imamura, Daiki Miki, Kazuaki Chayama, Yuji Ishida
Publikováno v:
Journal of General Virology. 98:1040-1047
Urokinase-type plasminogen activator/severe combined immunodeficiency (uPA/SCID) mice transplanted with human hepatocytes are permissive for hepatitis B virus (HBV) and hepatitis C virus (HCV) infection. However, one of the problems affecting uPA tra
Autor:
Ding Wang, Ki Buom Lee, Gautam S.D. Balasubramania Pandian, Neha Akkad, Donnele Daley, Constantinos P. Zambirinis, Berk Aykut, Beatrix Ueberheide, George Miller, Brian Diskin, Shruti Nayak, Alejandro Torres-Hernandez, Lara K. Mahal, Steven Chang, Vishnu R. Mani, Gregor Werba, Robert Rodriguez, Lawrence B. Gardner, Atsuo Ochi, Shivraj Savadkar, Navyatha Mohan, Rocky Barilla, Mautin Hundeyin, Daniel W. Heindel
Publikováno v:
Nature medicine
The progression of pancreatic oncogenesis requires immune-suppressive inflammation in cooperation with oncogenic mutations. However, the drivers of intratumoral immune tolerance are uncertain. Dectin 1 is an innate immune receptor crucial for anti-fu
Autor:
Rocky Barilla, Rae S. Rokosh, Sushma Ravirala, Michael Deutsch, Muhammad Atif Salyana, Bruce E. Gelb, Johana Gutierrez, Stephanie H. Greco, George Miller, Donnele Daley, Clint Whiteman, Aleksandr Kalabin, Alejandro Torres-Hernandez, Vishnu R. Mani, Yuriy Nikifrov, Savitha Nagaraj, Mautin Hundeyin, Karla Tejada, Atsuo Ochi, Lena Seifert, Steven C. Katz
Publikováno v:
The Journal of Immunology. 197:2816-2827
Con A hepatitis is regarded as a T cell–mediated model of acute liver injury. Mincle is a C-type lectin receptor that is critical in the immune response to mycobacteria and fungi but does not have a well-defined role in preclinical models of non-pa
Autor:
Hiroshi Shiku, Kiyotaka Kuzushima, Takashi Sugiyama, Fumihiro Ochi, Nicholas Casey, Hiroshi Fujiwara, A. John Barrett, Hiroki Tanaka, Junichi Mineno, Masaki Yasukawa, Kazushi Tanimoto, Sachiko Okamoto
Publikováno v:
Clinical Cancer Research. 22:4405-4416
Purpose: Mogamulizumab (Mog), a humanized anti-CC chemokine receptor 4 (CCR4) mAb that mediates antibody-dependent cellular cytotoxicity (ADCC) using FcγR IIIa (CD16)-expressing effector cells, has recently been approved for treatment of CCR4-positi
Autor:
Susumu Nakae, Toshiro Takai, Sakiko Shimura, Ko Okumura, Hideo Iida, Mutsuko Hara, Izumi Nishioka, Natsuko Maruyama, Shigaku Ikeda, Hideoki Ogawa, Akira Matsuda, Hirohisa Saito, Seiji Kamijo, Hirono Ochi
Publikováno v:
Journal of Investigative Dermatology. 136:1408-1417
Allergen sources such as mites, insects, fungi, and pollen contain proteases. Airway exposure to proteases induces allergic airway inflammation and IgE/IgG1 responses via IL-33-dependent mechanisms in mice. We examined the epicutaneous sensitization