Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Bart J.M. van Vlijmen"'
Autor:
Yvonne K. Jongejan, Jimmy F.P. Berbée, Jeroen Eikenboom, Marion J.J. Gijbels, Bart J.M. van Vlijmen
Publikováno v:
Journal of Thrombosis and Thrombolysis
Journal of Thrombosis and Thrombolysis, 52(3), 715-719. Springer, Cham
Journal of thrombosis and thrombolysis, 52(3), 715-719. Springer Netherlands
Journal of Thrombosis and Thrombolysis, 52, 715-719. SPRINGER
Journal of Thrombosis and Thrombolysis, 52(3), 715-719. Springer, Cham
Journal of thrombosis and thrombolysis, 52(3), 715-719. Springer Netherlands
Journal of Thrombosis and Thrombolysis, 52, 715-719. SPRINGER
Murine atherosclerosis models are key for investigation of atherosclerosis pathophysiology and drug development. However, they do not feature spontaneous atherothrombosis as a final stage of atherosclerosis. Transgenic mice expressing both the human
Publikováno v:
Seminars in Thrombosis and Hemostasis. 33:610-616
During the last 15 years, transgenic mice have been generated that carry defective and/or mutant alleles of the natural anticoagulant pathways and display a spontaneous thrombotic phenotype. With the generation of these mouse lines, better opportunit
Autor:
Wouter Jukema, Erik A.L. Biessen, Anita van Nieuwkoop, Nuno Pires, Bart J.M. van Vlijmen, Ko Willems van Dijk, Susanne Zadelaar, Louis M. Havekes, Lianne S.M. Boesten
Publikováno v:
Transgenic Research. 15:31-36
Here we describe a means to conditionally modify genes at a predefined and localized region of the vasculature using a perivascular drug delivery device (PDD). A 4-hydroxytamoxifen (4-OHT)-eluting PDD was applied around the carotid or femoral artery
Autor:
Ko Willems van Dijk, Bart J.M. van Vlijmen, H. Belinda van't Hof, Patrick J. van Gorp, Hans van der Boom, M. L. Breuer, Andre van der Zee, Louis M. Havekes, Marten H. Hofker
Publikováno v:
Journal of Biological Chemistry. 271:30595-30602
Apolipoprotein E*2(Arg-155 → Cys) (APOE*2) transgenic mice were generated and compared to the previously generated apolipoprotein E*3- Leiden (APOE*3-Leiden) transgenic mice to study the variable expression of hyperlipoproteinemia associated with t
Autor:
Hans M.G. Princen, Sonia M. S. Espirito Santo, Jacques Auger, Ingrid Arnault, Wim van Duyvenvoorde, Louis M. Havekes, Bart J.M. van Vlijmen, E.H. Offerman
Publikováno v:
Atherosclerosis. 177(2)
Numerous animal studies have reported that garlic can protect against atherosclerosis. However, a comparable number of studies do not support this observation. This contradiction may result from differences in study design, use of different animal mo
Autor:
Harry van Goor, Louis M. Havekes, Frank Apostel, Miek C. Jong, Marten H. Hofker, Folkert Kuipers, Arjen R. Mensenkamp, Vincent W. Bloks, Jobst Greeve, Marja J. A. van Luyn, Bart J.M. van Vlijmen
Publikováno v:
Journal of Hepatology, 33(2), 189-198. ELSEVIER SCIENCE BV
University of Groningen
University of Groningen
Background/Aim: Apolipoprotein (apo) E-deficiency leads to hepatic steatosis and impaired Very Low Density Lipoprotein (VLDL)-triglyceride production rates in mice. A mutant apoE isoform, apoE3-Leiden, is associated with a dominantly inherited form o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91fd82f6155a2ac697342197e848c4fc
https://research.rug.nl/en/publications/f8f80337-4a4e-4103-9da3-8571a4840925
https://research.rug.nl/en/publications/f8f80337-4a4e-4103-9da3-8571a4840925
Autor:
Louis M. Havekes, Marion J.J. Gijbels, Menno P. J. De Winther, Joris J Heus, Alida C van den Bos, Marten H. Hofker, Bart J.M. van Vlijmen, Marco Breuer, Rune R. Frants, Ko Willems van Dijk, Edwin R Wijers
Publikováno v:
Atherosclerosis, 147(2), 339-347. Elsevier Ireland Ltd
Atherosclerosis, 2, 147, 339-347
Atherosclerosis, 2, 147, 339-347
Macrophage scavenger receptors class A (MSR) are thought to play an important role in atherogenesis by mediating the unrestricted uptake of modified lipoproteins by macrophages in the vessel wall leading to foam cell formation. To investigate the in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::342096c97e7dca39d393769307449453
https://pure.amc.nl/en/publications/macrophage-specific-overexpression-of-the-human-macrophage-scavenger-receptor-in-transgenic-mice-using-a-180kb-yeast-artificial-chromosome-leads-to-enhanced-foam-cell-formation-of-isolated-peritoneal-macrophages(57ddc1cc-90b4-4a52-8831-7598fc2f8720).html
https://pure.amc.nl/en/publications/macrophage-specific-overexpression-of-the-human-macrophage-scavenger-receptor-in-transgenic-mice-using-a-180kb-yeast-artificial-chromosome-leads-to-enhanced-foam-cell-formation-of-isolated-peritoneal-macrophages(57ddc1cc-90b4-4a52-8831-7598fc2f8720).html