Zobrazeno 1 - 10
of 272
pro vyhledávání: '"Ochi A"'
Autor:
Arisa Ochi, Yasumasa Ikeda, Naoki Kashihara, Kojiro Nagai, Kensei Taguchi, Masanori Tamaki, Ken-ichi Aihara, Hideharu Abe, Masashi Miyoshi, Craig R. Brooks, Hiroyuki Kadoya, Kenji Nishimura, Seiji Kishi
Publikováno v:
Biochemical and Biophysical Research Communications. 556:142-148
The relationship between cellular senescence and fibrosis in the kidney is being elucidated and we have identified it as therapeutic target in recent studies. Chronic kidney disease has also become a lifestyle disease, often developing on the backgro
Publikováno v:
Neuroscience Research. 165:45-50
Chronic fatigue syndrome (CFS) is characterized by long-lasting fatigue, and a range of symptoms, and is involved in homeostasis disruption. CFS patients frequently complain of low grade fever or chill even under normal body temperature indicating th
Autor:
Kensuke Senzaki, Michiya Igase, Yasumasa Ohyagi, Sho-ichi Yamagishi, Keiji Igase, Masayuki Ochi, Yoko Okada, Sayaka Matsumoto
Publikováno v:
Rejuvenation Research. 24:97-103
Casein hydrolysate has been shown to improve arterial stiffness as estimated by brachial-ankle pulse wave velocity (baPWV) in untreated hypertensive patients. Facial pigmentation is associated with atherosclerosis, both of which are supposed to be mo
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 11, p e0259055 (2021)
PLoS ONE, Vol 16, Iss 11 (2021)
PLoS ONE, Vol 16, Iss 11, p e0259055 (2021)
PLoS ONE, Vol 16, Iss 11 (2021)
Objective To investigate the effect of systemic administration of salicylate as a tinnitus inducing drug in the auditory cortex of guinea pigs. Methods Extracellular recording of spikes of the primary auditory cortex and dorsocaudal areas in healthy
Autor:
Nobumitsu Hanioka, Takashi Isobe, Hideto Jinno, Toshiko Tanaka-Kagawa, Sadayuki Ochi, Susumu Ohkawara
Publikováno v:
Toxicology in Vitro. 54:237-242
Di(2-ethylhexyl) phthalate (DEHP) is a widely used plasticizer that is rapidly metabolized to mono(2-ethylhexyl) phthalate (MEHP), an active metabolite, in mammals. In the present study, the hydrolysis of DEHP by the liver and intestinal microsomes o
Autor:
Hisao Nishijo, Susumu Urakawa, Takaya Oshima, Son Tien Nguyen, Naoto Fujita, Natsuki Goto, Kaho Takaishi, Ryosuke Ochi
Publikováno v:
PLoS ONE, Vol 16, Iss 9, p e0256655 (2021)
PLoS ONE
PLoS ONE
Metabolic disorders are associated with a higher risk of psychiatric disorders. We previously reported that 20-week-old Otsuka Long-Evans Tokushima fatty (OLETF) rats, a model of progressive type 2 diabetes, showed increased anxiety-like behavior and
Autor:
Takuya Oyaizu, Toshio Miyata, Yoshinori Asou, Yoichi Ezura, Aidehamu Aihemaiti, Kunikazu Tsuji, Naoki Yamamoto, Shingo Sato, Jinying Piao, Atsushi Okawa, Hiroki Ochi
Publikováno v:
Biochemical and biophysical research communications. 534
Sarcopenia is among the most common medical problems of the aging population worldwide and a major social concern. Here, we explored the therapeutic potential of TM5484, a novel orally available PAI-1 inhibitor, to prevent sarcopenia. The sarcopenic
Autor:
Hisao Nishijo, Son Tien Nguyen, Taketoshi Ono, Duc Trung Le, Naoto Fujita, Kojiro Matsushita, Natsuki Goto, Ryosuke Ochi, Susumu Urakawa
Publikováno v:
The journal of physiological sciences : JPS. 70(1)
Metabolic disorders can induce psychiatric comorbidities. Both brain and neuronal composition imbalances reportedly induce an anxiety-like phenotype. We hypothesized that alterations of localized brain areas and cholecystokinin (CCK) and parvalbumin
Autor:
Hiroshi Kumon, Naoki Abe, Jun-ichi Iga, Shuken Boku, Keisuke Sekiya, Shu-ichi Ueno, Tasuku Nishihara, Yuta Yoshino, Yu Funahashi, Shinichiro Ochi
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
The pathophysiology of delayed carbon monoxide (CO) encephalopathy remains unclear. In this study, the effects of CO exposure on the dentate gyrus (DG) were investigated in a Wistar rat model by histochemical and molecular methods. Model rats showed
Autor:
Wataru Nino, Natsuki Goto, Hisao Nishijo, Kazuyoshi Hisatsune, Ryosuke Ochi, Susumu Urakawa, Naoto Fujita
Publikováno v:
Biomedical research (Tokyo, Japan). 41(1)
Mild hyperbaric treatment prevents type 2 diabetes progression due to increased oxygen concentration and blood flow in skeletal muscle. However, it remains unknown whether this treatment is effective during all stages of type 2 diabetes. This study a