Zobrazeno 1 - 10
of 284 653
pro vyhledávání: '"medicine"'
Autor:
Tonya Orchard, Tial TinKai, Rachel M. Cole, A. Courtney DeVries, Rebecca Andridge, Kate Ormiston, Maryam B. Lustberg, Julie Fitzgerald, Monica M. Gaudier-Diaz
Publikováno v:
Nutritional neuroscience. 25(12)
Chemotherapy can result in toxic side effects in the brain. Intake of marine-based omega-3 polyunsaturated fatty acids (n-3 PUFAs), eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), alter brain fatty acids, potentially improving brain funct
Autor:
Natalie R. Harris, László Bálint, Danielle M. Dy, Natalie R. Nielsen, Hernán G. Méndez, Amir Aghajanian, Kathleen M. Caron
Publikováno v:
Physiological reviews. 103(1)
The heart is imbued with a vast lymphatic network that is responsible for fluid homeostasis and immune cell trafficking. Disturbances in the forces that regulate microvascular fluid movement can result in myocardial edema, which has profibrotic and p
Publikováno v:
Cold Spring Harbor perspectives in medicine. 11(12)
Experimental preclinical models have been a cornerstone of lung cancer translational research. Work in these model systems has provided insights into the biology of lung cancer subtypes and their origins, contributed to our understanding of the mecha
Autor:
Real, Caroline Cristiano, Binda, Karina Henrique, Thomsen, Majken Borup, Lillethorup, Thea Pinholt, Brooks, David James, Landau, Anne M
Publikováno v:
Real, C C, Binda, K H, Thomsen, M B, Lillethorup, T P, Brooks, D J & Landau, A M 2023, ' Selecting the Best Animal Model of Parkinson's Disease for Your Research Purpose : Insight from in vivo PET Imaging Studies ', Current Neuropharmacology, vol. 21, no. 5, pp. 1241-1272 . https://doi.org/10.2174/1570159X21666230216101659
Abstract: Parkinson’s disease (PD) is a debilitating neurodegenerative multisystem disorder leading to motor and non-motor symptoms in millions of individuals. Despite intense research, there is still no cure, and early disease biomarkers are lacki
Autor:
Xin Wei, Gang Zhao, Zhenshan Jia, Zhifeng Zhao, Ningrong Chen, Yuanyuan Sun, Matthew Kelso, Geetanjali Rathore, Dong Wang
Publikováno v:
Molecular pharmaceutics. 19(11)
Traumatic brain injury (TBI) is one of the leading causes of death and disability among children and young adults in the United States. In this manuscript, we assessed the utility of an
Publikováno v:
Scandinavian journal of rheumatology. 51(6)
The Wnt signalling antagonist Dickkopf-1 (DKK1) inhibits osteoblast differentiation and function and has been described to play a central role in promoting bone loss, while blockade of DKK1 increases bone formation. We investigated the effects of DKK
Publikováno v:
AIDS reviews. 24(3)
Although the world is currently focused on the COVID-19 pandemic, HIV/AIDS remains a significant threat to public health. To date, the HIV/AIDS pandemic has claimed the lives of over 36 million people, while nearly 38 million people are currently liv
Autor:
Natsuko Macabuag, William Esmieu, Perla Breccia, Rebecca Jarvis, Wesley Blackaby, Ovadia Lazari, Liudvikas Urbonas, Maria Eznarriaga, Rachel Williams, Annelieke Strijbosch, Rhea Van de Bospoort, Kim Matthews, Cole Clissold, Tammy Ladduwahetty, Huw Vater, Patrick Heaphy, Douglas G. Stafford, Hong-Jun Wang, John E. Mangette, George McAllister, Vahri Beaumont, Thomas F. Vogt, Hilary A. Wilkinson, Elizabeth M. Doherty, Celia Dominguez
Publikováno v:
Journal of medicinal chemistry. 65(18)
Huntington's disease (HD) is a lethal autosomal dominant neurodegenerative disorder resulting from a CAG repeat expansion in the huntingtin (
Autor:
Etienne Abdelnour-Berchtold, Aadil Ali, Cristina Baciu, Erika L. Beroncal, Aizhou Wang, Olivia Hough, Mitsuaki Kawashima, Manyin Chen, Yu Zhang, Mingyao Liu, Tom Waddell, Ana C. Andreazza, Shaf Keshavjee, Marcelo Cypel
Publikováno v:
The Journal of Heart and Lung Transplantation. 41:1679-1688
Our recent work has challenged 4°C as an optimal lung preservation temperature by showing storage at 10°C to allow for the extension of preservation periods. Despite these findings, the impact of 10°C storage has not been evaluated in the setting
Publikováno v:
The Journal of Thoracic and Cardiovascular Surgery. 164:e333-e347
Background Patients surviving a myocardial infarction have progressive cardiac dysfunction and ventricular remodeling. Mitral regurgitation is often diagnosed in these patients, and is a risk factor that portends poor prognosis. Whether such post-inf