Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Kroemer G"'
Autor:
Villella, V. R., Esposito, S., Ferrari, E., Monzani, R., Tosco, A., Rossin, F., Castaldo, A., Silano, M., Marseglia, G. L., Romani, L., Barlev, N. A., Piacentini, M., Raia, V., Kroemer, G., Maiuri, L.
Publikováno v:
Cell Death & Disease
Cell Death and Disease
Cell Death and Disease, Nature Publishing Group, 2019, 10 (4), pp.258. ⟨10.1038/s41419-019-1500-x⟩
Cell Death and Disease, Vol 10, Iss 4, Pp 1-11 (2019)
Cell Death and Disease
Cell Death and Disease, Nature Publishing Group, 2019, 10 (4), pp.258. ⟨10.1038/s41419-019-1500-x⟩
Cell Death and Disease, Vol 10, Iss 4, Pp 1-11 (2019)
International audience; Under physiological conditions, a finely tuned system of cellular adaptation allows the intestinal mucosa to maintain the gut barrier function while avoiding excessive immune responses to non-self-antigens from dietary origin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::18f9020bda3ee58d2bc5986e9cf47f56
http://hdl.handle.net/2108/233021
http://hdl.handle.net/2108/233021
Autor:
Marco Silano, Guido Kroemer, Valeria Raia, Manuela D’Eletto, Alice Castaldo, Mauro Piacentini, Romina Monzani, Gianni Bona, Antonella Tosco, Eleonora Ferrari, Speranza Esposito, Luigina Romani, Valeria Rachela Villella, Gian Luigi Marseglia, Alessandro Luciani, Luigi Maiuri, Federica Rossin
Publikováno v:
Aging (Albany NY)
In celiac disease (CD), an intolerance to dietary gluten/gliadin, antigenic gliadin peptides trigger an HLA-DQ2/DQ8-restricted adaptive Th1 immune response. Epithelial stress, induced by other non-antigenic gliadin peptides, is required for gliadin t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ca96466391451a1f2ff22b7019e4397
http://hdl.handle.net/11588/770638
http://hdl.handle.net/11588/770638
Autor:
Mara C. Spinella, Romina Monzani, Luigi Maiuri, Alessandro Luciani, Federica Rossin, Mauro Piacentini, Giorgia Renga, Christian Grimm, Guido Kroemer, Marco Silano, Valeria Raia, Enrico Garaci, Stefano Guido, Vasilis Oikonomou, Antonella Tosco, Valeria Rachela Villella, Andrea Venerando, Giorgio Cozza, Eleonora Ferrari, Speranza Esposito, Yu-Kai Chao, Luigina Romani
Publikováno v:
The EMBO Journal
Intestinal handling of dietary proteins usually prevents local inflammatory and immune responses and promotes oral tolerance. However, in ~ 1% of the world population, gluten proteins from wheat and related cereals trigger an HLA DQ2/8‐restricted T
Autor:
Guido Kroemer, Massimo Pettoello-Mantovani, Marco Silano, Bob J. Scholte, Ilaria Russo, Stefano Guido, Valeria Raia, Antonella De Matteis, Valeria Rachela Villella, Manuela Gavina, Alessandro Luciani, Rosa Carnuccio, Luigi Maiuri, Maria Chiara Maiuri, Speranza Esposito, Alberto Luini
Publikováno v:
Autophagy 8 (2012): 1657–1672. doi:10.4161/auto.21483
info:cnr-pdr/source/autori:Luciani A, Villella VR, Esposito S, Gavina M, Russo I, Silano M, Guido S, Pettoello-Mantovani M, Carnuccio R, Scholte B, De Matteis MA, Maiuri MC, Raia V, Luini A, Kroemer G, Maiuri L/titolo:Targeting autophagy as a novel strategy for facilitating the therapeutic action of potentiators on Delta F508 cystic fibrosis transmembrane conductance regulator/doi:10.4161%2Fauto.21483/rivista:Autophagy/anno:2012/pagina_da:1657/pagina_a:1672/intervallo_pagine:1657–1672/volume:8
Autophagy, 8(11), 1657-1672. Landes Bioscience
info:cnr-pdr/source/autori:Luciani A, Villella VR, Esposito S, Gavina M, Russo I, Silano M, Guido S, Pettoello-Mantovani M, Carnuccio R, Scholte B, De Matteis MA, Maiuri MC, Raia V, Luini A, Kroemer G, Maiuri L/titolo:Targeting autophagy as a novel strategy for facilitating the therapeutic action of potentiators on Delta F508 cystic fibrosis transmembrane conductance regulator/doi:10.4161%2Fauto.21483/rivista:Autophagy/anno:2012/pagina_da:1657/pagina_a:1672/intervallo_pagine:1657–1672/volume:8
Autophagy, 8(11), 1657-1672. Landes Bioscience
Channel activators (potentiators) of cystic fibrosis (CF) transmembrane conductance regulator (CFTR), can be used for the treatment of the small subset of CF patients that carry plasma membrane-resident CFTR mutants. However, approximately 90% of CF
Autor:
Stefano, Daniela De, Villella, Valeria R, Esposito, Speranza, Tosco, Antonella, Sepe, Angela, Gregorio, Fabiola De, Salvadori, Laura, Grassia, Rosa, Leone, Carlo A, Rosa, Giuseppe De, Maiuri, Maria C, Pettoello-Mantovani, Massimo, Guido, Stefano, Bossi, Anna, Zolin, Anna, Venerando, Andrea, Pinna, Lorenzo A, Mehta, Anil, Bona, Gianni, Kroemer, Guido, Maiuri, Luigi, Raia, Valeria
Publikováno v:
Autophagy
Restoration of BECN1/Beclin 1-dependent autophagy and depletion of SQSTM1/p62 by genetic manipulation or autophagy-stimulatory proteostasis regulators, such as cystamine, have positive effects on mouse models of human cystic fibrosis (CF). These meas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::e9fef87ab129a66ae0edcd51d575077a
http://hdl.handle.net/11577/3103504
http://hdl.handle.net/11577/3103504
Autor:
Sara Lusa, I Sana, Guido Kroemer, P. Buonpensiero, C A Leone, Maria Chiara Maiuri, Eleonora Ferrari, Angela Sepe, Stefano Guido, G. De Rosa, Antonella Tosco, Gianni Bona, Speranza Esposito, Gautier Stoll, D. De Stefano, A. Di Pasqua, R. Grassia, Luigi Maiuri, Laura Salvadori, F. De Gregorio, Anil Mehta, Valeria Raia
Publikováno v:
Cell Death and Differentiation
We previously reported that the combination of two safe proteostasis regulators, cysteamine and epigallocatechin gallate (EGCG), can be used to improve deficient expression of the cystic fibrosis transmembrane conductance regulator (CFTR) in patients