Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Su, Zhen"'
Autor:
Xinyue Hu, Xiujun Liu, Lianqi Sun, Yong-Su Zhen, Yi Li, Jie Jin, Yanping Li, Yu‐cheng Wang, Qingfang Miao, Rong Wang, Zhuorong Li, A-Long Cui
Publikováno v:
Molecular Oncology
Molecular Oncology, Vol 13, Iss 2, Pp 246-263 (2019)
Molecular Oncology, Vol 13, Iss 2, Pp 246-263 (2019)
Epidermal growth factor receptor (EGFR) is a rational target for cancer therapy, because its overexpression plays an important oncogenic role in a variety of solid tumors; however, EGFR-targeted antibody-drug conjugate (ADC) therapy for esophageal sq
Publikováno v:
Oncotarget
// Bing-yan Zhu 1 , Bo-yang Shang 1 , Yue Du 1 , Yi Li 1 , Liang Li 1 , Xian-dong Xu 1 , Yong-su Zhen 1 1 Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China Correspondence
Publikováno v:
Journal of Cancer Research and Therapeutics, Vol 12, Iss 1, Pp 182-187 (2016)
Aims: The aim of this study is to explore the antitumor efficacy of lidamycin (LDM) against human multiple myelomas (MM). Materials and Methods: Human MM RPMI 8226 cells and the xenograft model in nonobese diabetic/severe combined immunodeficient (NO
Autor:
Su-Zhen Wu, Hui Ching Lin, Yi-Chao Lee, Han-Fang Wu, Chi-Wei Lee, I-Tuan Chen, Chi-Chen Huang, Yi-Ju Chen, Chih-Wei Tang, Chung-Hsi Hsing
Publikováno v:
Neural Plasticity
Neural Plasticity, Vol 2017 (2017)
Neural Plasticity, Vol 2017 (2017)
Epoxyeicosatrienoic acids (EETs) are derived from arachidonic acid and metabolized by soluble epoxide hydrolase (sEH). The role of EETs in synaptic function in the central nervous system is still largely unknown. We found that pharmacological inhibit
Autor:
Xian-dong Xu, Zhi-Ling Zhu, Xiujun Liu, Boyang Shang, Shuying Wu, Yi Li, Shuyi Si, Yong-Su Zhen, Yan-Bo Zheng, Jinming Zhou, Jian-Hua Gong
Publikováno v:
Scientific Reports
Multidrug resistance is a major limitation for microtubule-binding agents in cancer treatment. Here we report a novel microtubule inhibitor (2-morpholin-4-yl-5-nitro-benzoic acid 4-methylsulfanyl-benzyl ester, IMB5046), its cytotoxicity against multi
Publikováno v:
Cancer Chemotherapy and Pharmacology. 69:1323-1332
As reported, epidermal growth factor receptor (EGFR) is over expressed in a variety of cancers including esophageal squamous cell carcinoma. Therefore, it becomes one of the potential targets for treating esophageal cancer. Pingyangmycin (PYM), a sin
Publikováno v:
Acta Pharmacologica Sinica. 30:1025-1032
To investigate the effects of lidamycin (LDM) on a mouse myeloma cell line (SP2/0) and human multiple myeloma cell lines (U266 and SKO-007), and provide the basis for the use of LDM in cancer therapy.A 3-[4,5-dimethylthiazol-2-yl]5-[3-carboxymethoxyp
Publikováno v:
The American Journal of Chinese Medicine. 37:923-931
In previous studies, rhein, one of the major bioactive constituents in the rhizome of rhubarb, inhibited the proliferation of various human cancer cells. However, because of its water insolubility, the anti-tumor efficacy of rhein was limited in vivo
Publikováno v:
Cancer immunology, immunotherapy : CII. 63(12)
Tuftsin (TF) is an immunomodulator tetrapeptide (Thr-Lys-Pro-Arg) that binds to the receptor neuropilin-1 (Nrp1) on the surface of cells. Many reports have described anti-tumor activity of tuftsin to relate with nonspecific activation of the host imm
Publikováno v:
The FEBS journal. 280(11)
Mesenchymal stem cells have the potential to undergo commitment and differentiation into a variety of cell types, including osteoblasts, chondrocytes, myocytes and adipocytes. Growth differentiation factor 6 (Gdf6) is a member of the transforming gro