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A Network of High-Mobility Group Box Transcription Factors Programs Innate Interleukin-17 Production
Autor:
Véronique Lefebvre, Joonsoo Kang, Nidhi Malhotra, Leslie J. Berg, Catherine C. Yin, Ok Hyun Cho, Katelyn Sylvia, John E. Harris, Kavitha Narayan, Heather J. Melichar, M. Rashighi
Publikováno v:
Immunity. 38:681-693
Summary How innate lymphoid cells (ILCs) in the thymus and gut become specialized effectors is unclear. The prototypic innate-like γδ T cells (Tγδ17) are a major source of interleukin-17 (IL-17). We demonstrate that Tγδ17 cells are programmed b