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Publikováno v:
Biochemical and Biophysical Research Communications. 638:103-111
Skin is the biggest organ of the human body, which easily gets irritated by exposure to the sun. Skin photoaging and acute photodamage are caused by intense UV-B radiation. Therefore, it is imperative to find new compounds to prevent skin damage and
Autor:
Andrew K, Chojnacki, Saranya, Navaneetha Krishnan, Humberto, Jijon, Timothy E, Shutt, Pina, Colarusso, Derek M, McKay
Publikováno v:
Mitochondrion. 68:44-59
Mitochondrial dysfunction as defined by transcriptomic and proteomic analysis of biopsies or ultra-structure in transmission electron microscopy occurs in inflammatory bowel disease (IBD); however, mitochondrial dynamics in IBD have received minimal
Publikováno v:
Seminars in Cell & Developmental Biology. 133:74-82
Cells with subcellular lumens form some of the most miniature tubes in the tubular organs of animals. These are often crucial components of the system, executing functions at remote body locations. Unlike tubes formed by intercellular or autocellular
Publikováno v:
Reproduction. 165:103-111
In brief Oocyte quality and its NAD+ level decrease with time during in vitro culture. This study shows that nicotinamide riboside (NR) supplementation improves early embryonic development potential in post-ovulatory oocytes by decreasing the reactiv
Autor:
Tatiane Pereira Scarpelli, Eloisa Zanin Pytlowanciv, Maria Etelvina Pinto-Fochi, Sebastião Roberto Taboga, Rejane Maira Góes
Publikováno v:
Reproduction. 165:65-78
In brief Maternal obesity plus high-fat diet in breastfeeding induces stromal hyperplasia and diffuse acinar atrophy in the rat prostate at aging, related to dyslipidemia and testosterone reduction. The high-lipid nutritional environment from intraut
Autor:
Roenick P. Olmo, Yaovi M. H. Todjro, Eric R. G. R. Aguiar, João Paulo P. de Almeida, Flávia V. Ferreira, Juliana N. Armache, Isaque J. S. de Faria, Alvaro G. A. Ferreira, Siad C. G. Amadou, Ana Teresa S. Silva, Kátia P. R. de Souza, Ana Paula P. Vilela, Antinea Babarit, Cheong H. Tan, Mawlouth Diallo, Alioune Gaye, Christophe Paupy, Judicaël Obame-Nkoghe, Tessa M. Visser, Constantianus J. M. Koenraadt, Merril A. Wongsokarijo, Ana Luiza C. Cruz, Mariliza T. Prieto, Maisa C. P. Parra, Maurício L. Nogueira, Vivian Avelino-Silva, Renato N. Mota, Magno A. Z. Borges, Betânia P. Drumond, Erna G. Kroon, Mario Recker, Luigi Sedda, Eric Marois, Jean-Luc Imler, João T. Marques
Publikováno v:
Nature Microbiology 8 (2023) 1
Nature Microbiology, 8(1), 135-149
Nature Microbiology, 8(1), 135-149
Aedes aegypti and A. albopictus mosquitoes are the main vectors for dengue virus (DENV) and other arboviruses, including Zika virus (ZIKV). Understanding the factors that affect transmission of arboviruses from mosquitoes to humans is a priority beca
Publikováno v:
Aging. 14:9860-9876
Muscle mass decreases with aging, while the C-C motif chemokine ligand 2 (CCL2) increases with aging; in this context, CCL2 can be considered a potential aging-promoting factor. Thus, CCL2 knockout mice are expected to exhibit anti-aging effects incl
Autor:
Melanie H. Dietrich, Mikha Gabriela, Kitsanapong Reaksudsan, Matthew W. A. Dixon, Li-Jin Chan, Amy Adair, Stephanie Trickey, Matthew T. O'Neill, Li Lynn Tan, Sash Lopaticki, Julie Healer, Sravya Keremane, Alan F. Cowman, Wai-Hong Tham
Publikováno v:
Biochemical Journal. 479:2529-2546
Transmission blocking interventions can stop malaria parasite transmission from mosquito to human by inhibiting parasite infection in mosquitos. One of the most advanced candidates for a malaria transmission blocking vaccine is Pfs230. Pfs230 is the
Autor:
Hyunju Park, Jung A Shin, Jiwoo Lim, Seulgi Lee, Jung-Hyuck Ahn, Jihee Lee Kang, Youn-Hee Choi
Publikováno v:
Molecules and Cells. 45:950-962
Aging is a major risk factor for common neurodegenerative diseases. Although multiple molecular, cellular, structural, and functional changes occur in the brain during aging, the involvement of caveolin-2 (Cav-2) in brain ageing remains unknown. We i
Publikováno v:
Oxidative Medicine and Cellular Longevity. 2022:1-25
The liver is the largest digestive organ in the human body. The increasing incidence of chronic liver fibrosis is one of the major health challenges in the world. Liver fibrosis is a wound-healing response to acute or chronic cellular damage of liver