Zobrazeno 91 - 100
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Autor:
Xia Guo, Oluwaseun Adeyanju, Christudas Sunil, Venkatakirankumar Mandlem, Ayobami Olajuyin, Steven Huang, Shi-You Chen, Steven Idell, Torry A. Tucker, Guoqing Qian
Publikováno v:
Am J Physiol Cell Physiol
Idiopathic pulmonary fibrosis (IPF) is the most common chronic interstitial lung disease and is characterized by progressive scarring of the lung. Transforming growth factor-β (TGF-β) signaling plays an essential role in IPF and drives fibroblast t
Publikováno v:
Cell Cycle
circFCHO2 has been revealed to be overexpressed in gastric cancer (GC) patients. This article identified the function of circFCHO2 on GC progression. The expression of circFCHO2, miR-194-5p and JAK1 in 30 GC patients and cells was monitored by quanti
Autor:
Jessica B. Blackburn, Jacob A. Schaff, Sergey Gutor, Rui-Hong Du, David Nichols, Taylor Sherrill, Austin J. Gutierrez, Matthew K. Xin, Nancy Wickersham, Yong Zhang, Michael J. Holtzman, Lorraine B. Ware, Nicholas E. Banovich, Jonathan A. Kropski, Timothy S. Blackwell, Bradley W. Richmond
Publikováno v:
American journal of respiratory cell and molecular biology. 67(3)
Loss of secretory IgA (SIgA) is common in chronic obstructive pulmonary disease (COPD) small airways and likely contributes to disease progression. We hypothesized that loss of SIgA results from reduced expression of pIgR (polymeric immunoglobulin re
Autor:
Jae-Hyun Lee, Chang-Min Lee, Joyce H. Lee, Mun-Ock Kim, Jin Wook Park, Suchitra Kamle, Bedia Akosman, Erica L. Herzog, Xue Yan Peng, Jack A. Elias, Chun Geun Lee
Publikováno v:
Am J Respir Cell Mol Biol
RationalePulmonary fibrosis is a devastating lung disease with few therapeutic options. Chitinase 1 (CHIT1), an 18 glycosyl hydrolase family member, contributes to the pathogenesis of pulmonary fibrosis through regulation of Transforming Growth Facto
Autor:
Laurynne C. Coates, Sierra D. Durham, David H. Storms, Andrew D. Magnuson, Diane L. Van Hekken, Benjamin M. Plumier, John W. Finley, Naomi K. Fukagawa, Peggy M. Tomasula, Danielle G. Lemay, Matthew J. Picklo, Daniela Barile, Kenneth F. Kalscheur, Mary E. Kable
Publikováno v:
Microbiology spectrum, vol 11, iss 3
Milk oligosaccharides (MOs) can be prebiotic and antiadhesive, while fatty acids (MFAs) can be antimicrobial. Both have been associated with milk microbes or mammary gland inflammation in humans. Relationships between these milk components and milk m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c28bffd65fa0e65e9a0bea3a737b378
https://escholarship.org/uc/item/24d562fv
https://escholarship.org/uc/item/24d562fv
An mRNA processing pathway suppresses metastasis by governing translational control from the nucleus
Autor:
Albertas Navickas, Hosseinali Asgharian, Juliane Winkler, Lisa Fish, Kristle Garcia, Daniel Markett, Martin Dodel, Bruce Culbertson, Sohit Miglani, Tanvi Joshi, Keyi Yin, Phi Nguyen, Steven Zhang, Nicholas Stevers, Hun-Way Hwang, Faraz Mardakheh, Andrei Goga, Hani Goodarzi
Publikováno v:
Nature cell biology, vol 25, iss 6
Cancer cells often co-opt post-transcriptional regulatory mechanisms to achieve pathologic expression of gene networks that drive metastasis. Translational control is a major regulatory hub in oncogenesis; however, its effects on cancer progression r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ba97ac6204b87cfd1b8c286a7d951fc
https://escholarship.org/uc/item/0rw7759t
https://escholarship.org/uc/item/0rw7759t
Autor:
Raymond Kiu, Alexander G. Shaw, Kathleen Sim, Antia Acuna-Gonzalez, Christopher A. Price, Harley Bedwell, Sally A. Dreger, Wesley J. Fowler, Emma Cornwell, Derek Pickard, Gusztav Belteki, Jennifer Malsom, Sarah Phillips, Gregory R. Young, Zoe Schofield, Cristina Alcon-Giner, Janet E. Berrington, Christopher J. Stewart, Gordon Dougan, Paul Clarke, Gillian Douce, Stephen D. Robinson, J. Simon Kroll, Lindsay J. Hall
Clostridium perfringens is an anaerobic toxin-producing bacterium associated with intestinal diseases, particularly in neonatal humans and animals. Infant gut microbiome studies have recently indicated a link between C. perfringens and the preterm in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c99cb2b07e2fd2a5bdf9eb9e6d97321b
https://www.repository.cam.ac.uk/handle/1810/350553
https://www.repository.cam.ac.uk/handle/1810/350553
Autor:
Yueming Cao, Jahnavi Rudrakshala, River Williams, Shade Rodriguez, Parand Sorkhdini, Alina X. Yang, Miles Mundy, Dongqin Yang, Amy Palmisciano, Thomas Walsh, Cesar Delcompare, Tanis Caine, Luca Tomasi, Barry S. Shea, Yang Zhou
Publikováno v:
American journal of respiratory cell and molecular biology. 67(2)
Idiopathic pulmonary fibrosis (IPF) is a particularly deadly form of pulmonary fibrosis of unknown cause. In patients with IPF, high serum and lung concentrations of CHI3L1 (chitinase 3 like 1) can be detected and are associated with poor survival. H
Autor:
Jian Wang, Zichao Feng, Zhaoyang Zhong, Qichao Qi, Wenjie Li, Jiwei Wang, Ning Yang, Qing Zhang, Bin Huang, Chen Qiu, Xiaofei Liu, Yaotian Hu, Anjing Chen, Wenxing Jin, Wenjing Zhou, Zhiyi Xue
Publikováno v:
Cell Cycle
Background: Nucleolar and spindle associated protein 1 (NUSAP1) is an indispensable mitotic regulator, which has been reported to be involved in the development, progression, and metastasis of several types of cancer. Here, we investigated the expres
Autor:
Victor Shamanskiy, Alina A. Mikhailova, Evgenii O. Tretiakov, Kristina Ushakova, Alina G. Mikhailova, Sergei Oreshkov, Dmitry A. Knorre, Natalia Ree, Jonathan B. Overdevest, Samuel W. Lukowski, Irina Gostimskaya, Valerian Yurov, Chia-Wei Liou, Tsu-Kung Lin, Wolfram S. Kunz, Alexandre Reymond, Ilya Mazunin, Georgii A. Bazykin, Jacques Fellay, Masashi Tanaka, Konstantin Khrapko, Konstantin Gunbin, Konstantin Popadin
Publikováno v:
BMC Biology. 21
Background Aging in postmitotic tissues is associated with clonal expansion of somatic mitochondrial deletions, the origin of which is not well understood. Such deletions are often flanked by direct nucleotide repeats, but this alone does not fully e