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Publikováno v:
Journal of Molecular Histology. 53:903-914
Fetal or neonatal androgen exposure has a programming effect on ovarian function inducing a polycystic ovarian syndrome-like condition. Its effects on uterine structure and function are poorly studied. The aim of this work was to characterize the tem
Autor:
Abhishek Mishra, Rubal Singla, Rohit Kumar, AmitRaj Sharma, Rupa Joshi, Phulen Sarma, Gurjeet Kaur, Manisha Prajapat, Alka Bhatia, Bikash Medhi
Publikováno v:
ACS Chemical Neuroscience. 13:2942-2961
Chronic neuroinflammation-induced anomalous glutamate receptor activation has been identified as one of the important factors in the pathogenesis of autism spectrum disorder (ASD). Thus, the current study was designed to elucidate the neuroprotective
Autor:
Qianlei Zhao, Tingting Chen, Chao Ni, Yingying Hu, Yan Nan, Wei Lin, Yanli Liu, Feixia Zheng, Xulai Shi, Zhongdong Lin, Jianghu Zhu, Zhenlang Lin
Publikováno v:
ACS Chemical Neuroscience. 13:2897-2912
The blood-brain barrier (BBB) is an important physiological barrier of the human body contributing to maintaining brain homeostasis and normal function. Hypoxic-ischemic (HI)-related brain injury is one of the main causes of neonatal acute morbidity
Publikováno v:
ACS Chemical Neuroscience. 13:2728-2742
Transient receptor potential canonical 5 (TRPC5) channels are predominantly expressed in the striatum and substantia nigra of the brain. These channels are permeable to calcium ions and are activated by oxidative stress. The physiological involvement
Autor:
Radiana D Antarianto, Amer Mahmood, Angela Giselvania, Ayu AA Prima Asri Dewi, Jatmiko Gustinanda, Jeanne Adiwinata Pawitan
Publikováno v:
Journal of Molecular Histology. 53:611-621
End-stage liver disease (ESLD) is a term used clinically in reference to a group of liver diseases with liver transplantation as the choice of treatment. Due to the limitations of liver transplantation, alternative treatments are needed. The use of p
Autor:
Ahmed Morsy, Krishnaiah Maddeboina, Ju Gao, Hezhen Wang, Juan Valdez, Louise F. Dow, Xinglong Wang, Paul C. Trippier
Publikováno v:
ACS Chemical Neuroscience. 13:2176-2190
Alzheimer's disease (AD) is the most common dementia affecting one in nine people over 65. Only a handful of small-molecule drugs and the anti-β amyloid (Aβ) antibody aducanumab are approved to treat AD. However, they only serve to reduce symptoms
Autor:
Manoj P. Dandekar, Mani Surya Kumar Palepu, Srilakshmi Satti, Yash Jaiswal, Aditya A. Singh, Surya Prakash Dash, Siva Nageswara Rao Gajula, Rajesh Sonti
Publikováno v:
ACS Chemical Neuroscience. 13:1948-1965
Depression is a debilitating mental disorder that affects322 million people worldwide. Despite the availability of several antidepressant agents, many patients remain treatment refractory. A growing literature study has indicated the role of gut micr
Autor:
Züleyha Doğanyiğit, Kaan Erbakan, Enes Akyuz, Ayse Kristina Polat, Alina Arulsamy, Mohd. Farooq Shaikh
Publikováno v:
ACS Chemical Neuroscience. 13:1835-1848
Traumatic brain injury (TBI) is a debilitating acquired neurological disorder that afflicts nearly 74 million people worldwide annually. TBI has been classified as more than just a single insult because of its associated risk toward various long-term
Autor:
Marianna Danková, Štefan Tóth, Monika Holodová, Zuzana Fagová, Kristína Čurgali, Eva Mechírová, Milan Maretta, Radomíra Nemcová, Soňa Gancarčíková, Štefan Polák
Publikováno v:
Journal of Molecular Histology. 53:773-780
The enteric nervous system (ENS), considered as separate branch of the autonomic nervous system, is located throughout the length of the gastrointestinal tract as a series of interconnected ganglionic plexuses. Recently, the ENS is getting more in th
Autor:
Joanne F Garbincius, John W. Elrod
Publikováno v:
Physiol Rev
The uptake of calcium into and extrusion of calcium from the mitochondrial matrix is a fundamental biological process that has critical effects on cellular metabolism, signaling, and survival. Disruption of mitochondrial calcium (mCa2+) cycling is im