Zobrazeno 31 - 40
of 42 195
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Autor:
Jie Mei, Huixiang Tian, Hsuan-Shun Huang, Nayiyuan Wu, Yu-Ligh Liou, Tang-Yuan Chu, Jing Wang, Wei Zhang
Publikováno v:
Cell Cycle. 22:85-99
High-grade serous ovarian cancer (HGSOC) is the most common and malignant type of ovarian cancer, accounting for 70%-80% of mortality. However, the treatment of HGSOC has improved little in the past few decades. Metformin is the first-line medication
Autor:
Caren Nádia Soares de Sousa, Ingridy da Silva Medeiros, Germana Silva Vasconcelos, Gabriel Ângelo de Aquino, Francisco Maurício Sales Cysne Filho, Jamily Cunha de Almeida, Ana Paula Negreiros Nunes Alves, Danielle S. Macêdo, Luzia Kalyne Almeida Moreira Leal, Silvânia Maria Mendes Vasconcelos
Publikováno v:
Oxidative Medicine and Cellular Longevity. 2022:1-14
Anxiety disorders are the most prevalent psychiatric disorders being also a comorbid state of other diseases. We aimed to evaluate the anxiolytic-like effects of carvedilol (CVD), a drug used to treat high blood pressure and heart failure with potent
Publikováno v:
Journal of Anatomy. 241:951-965
The cranial casques of modern cassowaries (Casuarius) have long intrigued researchers; however, in-depth studies regarding their morphological variation are scarce. Through visual inspection, it has been recognized that casque variability exists betw
Publikováno v:
Biochemical and Biophysical Research Communications. 616:104-109
Dosage compensation is a process that produces a similar expression of sex-linked and autosomal genes. In the silkworm Bombyx mori with a WZ sex-determination system, the expression from the single Z in WZ females matches that of ZZ males due to the
Publikováno v:
Biochemical and Biophysical Research Communications. 617:41-47
Parkinson's disease (PD) is the second most common neurodegenerative disease worldwide, with the incidence in men being about twice as compared to women. Gender differences may provide clues for finding key targets that mediate the death of dopaminer
Autor:
Veronica Pena-Leon, Cintia Folgueira, Silvia Barja-Fernández, Raquel Pérez-Lois, Natália Da Silva Lima, Marion Martin, Violeta Heras, Sara Martinez-Martinez, Paola Valero, Cristina Iglesias, Mannon Duquenne, Omar Al-Massadi, Daniel Beiroa, Yara Souto, Miguel Fidalgo, Rasika Sowmyalakshmi, Diana Guallar, Juan Cunarro, Cecilia Castelao, Ana Senra, Patricia González-Saenz, Rocío Vázquez-Cobela, Rosaura Leis, Guadalupe Sabio, Helge Mueller-Fielitz, Markus Schwaninger, Miguel López, Sulay Tovar, Felipe F. Casanueva, Emmanuel Valjent, Carlos Diéguez, Vincent Prevot, Rubén Nogueiras, Luisa M. Seoane
Publikováno v:
Nature Metabolism
Nature Metabolism, 2022, 4 (7), pp.901-917. ⟨10.1038/s42255-022-00602-z⟩
Nature Metabolism, 2022, 4 (7), pp.901-917. ⟨10.1038/s42255-022-00602-z⟩
Early-life determinants are thought to be a major factor in the rapid increase of obesity. However, while maternal nutrition has been extensively studied, the effects of breastfeeding by the infant on the reprogramming of energy balance in childhood
Publikováno v:
Stem Cells. 40:919-931
Intrauterine adhesion (IUA) is characterized by the presence of fibrosis in the uterine cavity. It is mainly caused by infection or trauma to the endometrium, and it imposes a great challenge to female reproductive health. Mesenchymal stem cells (MSC
Autor:
Jianfang Huang, Yuling Mao, Quanxin Li, Honghai Hong, Ni Tang, Xiangjin Kang, Yuling Huang, Jianqiao Liu, Qing Gong, Yachao Yao, Lei Li
Publikováno v:
Journal of Cellular and Molecular Medicine. 26:4613-4623
Angiogenesis and increased permeability are essential pathological basis for the development of ovarian hyperstimulation syndrome (OHSS). Kallistatin (KS) is an endogenous anti-inflammatory and anti-angiogenic factor that participates in a variety of
Publikováno v:
Cell Cycle
Excessive apoptosis of placental trophoblast cells is considered a major cause of pre-eclampsia (PE) pathogenesis. Phosphorylation of the widely expressed cAMP response element binding protein (CREB) regulates apoptosis and may be involved in PE inci
Autor:
Ruopeng Tan, Tao Cong, Guiwen Xu, Zhujing Hao, Jiawei Liao, Yunpeng Xie, Yajuan Lin, Xiaolei Yang, Qingsong Li, Yang Liu, Yun-Long Xia
Publikováno v:
Antioxidants & Redox Signaling. 37:19-39