Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Bin Xiao"'
Publikováno v:
Skeletal Muscle
Skeletal Muscle, Vol 9, Iss 1, Pp 1-16 (2019)
Skeletal Muscle, Vol 9, Iss 1, Pp 1-16 (2019)
Background Growth differentiation factor 11 (GDF11) is a member of the transforming growth factor β superfamily. The GDF11 propeptide, which is derived from the GDF11 precursor protein, blocks the activity of GDF11 and its homolog, myostatin, which
Autor:
Pei Juan Lu, Xiao Xiao, Chunping Qiao, Lei Xu, Qi Long Lu, Chi Hsien Wang, Derek J. Blake, Bin Xiao, Elizabeth Keramaris
Publikováno v:
Molecular Therapy. 21(10):1832-1840
Mutations in the FKRP gene are associated with a wide range of muscular dystrophies from mild limb-girdle muscular dystrophy (LGMD) 2I to severe Walker–Warburg syndrome and muscle-eye-brain disease. The characteristic biochemical feature of these d
Autor:
Xiao Xiao, Bin Xiao, H Yan, Chunping Qiao, G F Shen, Dao Wen Wang, Jiangang Jiang, Jianbin Li
Publikováno v:
Gene therapy. 24(3)
Inhibition of myostatin, a negative growth modulator for muscle, can functionally enhance muscle mass and improve glucose and fat metabolism in myostatin propeptide (MPRO) transgenic mice. This study was to investigate whether myostatin inhibition by
Autor:
Elizabeth Keramaris-Vrantsis, Hsin I. Ma, Chunping Qiao, Juan Li, Chi Hsien Wang, Hui Zheng, Jiangang Jiang, Ruhang Tang, Peijuan Lu, Yiumo Michael Chan, Qilong Lu, Bin Xiao, Xiao Xiao
Publikováno v:
The American Journal of Pathology. 178:261-272
Limb-girdle muscular dystrophy 2I (LGMD2I) is caused by mutations in the fukutin-related protein (FKRP) gene. Unlike its severe allelic forms, LGMD2I usually involves slower onset and milder course without defects in the central nervous system. The l
Autor:
James W. Voltz, Guangtian Yang, Dao Wen Wang, Bin Xiao, Xuguang Li Li, Xuefeng Yu, Jiangtao Yan, Darryl C. Zeldin, Xiao Xiao
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 334:784-794
Cytochrome P450 (P450)-derived epoxyeicosatrienoic acids (EETs) exert well recognized vasodilatory, diuretic, and tubular fluid-electrolyte transport actions that are predictive of a hypotensive effect. The study sought to determine the improvement o