Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Colloca A"'
Autor:
Manfredi Di Lorenzo, Geraldina Signa, Carlotta Mazzoldi, Salvatrice Vizzini, Gabriele Boscolo Palo, Cristina Andolina, Francesco Colloca, Michele Gristina
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-15 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-15 (2020)
Elasmobranchs are among the species most threatened by overfishing and a large body of evidence reports their decline around the world. As they are large predators occupying the highest levels of marine food webs, their removal can alter the trophic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7bb94303004c5098e74e90f3150bba4
http://hdl.handle.net/11577/3344336
http://hdl.handle.net/11577/3344336
Autor:
Julie E, Ledgerwood, Adam D, DeZure, Daphne A, Stanley, Emily E, Coates, Laura, Novik, Mary E, Enama, Nina M, Berkowitz, Zonghui, Hu, Gyan, Joshi, Aurélie, Ploquin, Sandra, Sitar, Ingelise J, Gordon, Sarah A, Plummer, LaSonji A, Holman, Cynthia S, Hendel, Galina, Yamshchikov, Francois, Roman, Alfredo, Nicosia, Stefano, Colloca, Riccardo, Cortese, Robert T, Bailer, Richard M, Schwartz, Mario, Roederer, John R, Mascola, Richard A, Koup, Nancy J, Sullivan, Barney S, Graham, Sarah, Romano
Publikováno v:
New England Journal of Medicine. 376:928-938
BackgroundThe unprecedented 2014 epidemic of Ebola virus disease (EVD) prompted an international response to accelerate the availability of a preventive vaccine. A replication-defective recombinant chimpanzee adenovirus type 3–vectored ebolavirus v
Autor:
Andrew R. Williams, Alison M. Lawrie, Susanne H. Sheehy, Alexandra J. Spencer, Riccardo Cortese, Christian Epp, Katie J. Ewer, Samuel E. Moretz, Fenella D. Halstead, Kazutoyo Miura, Stefano Colloca, Matthew D. J. Dicks, Eleanor Berrie, Adrian V. S. Hill, Sarah C. Gilbert, Ian D. Poulton, Carole A. Long, Simon J. Draper, Sarah Moyle, Christopher J A Duncan, Sean C. Elias, Alfredo Nicosia, Katharine A. Collins
Efficacy trials of antibody-inducing protein-in-adjuvant vaccines targeting the blood-stage Plasmodium falciparum malaria parasite have so far shown disappointing results. The induction of cell-mediated responses in conjunction with antibody response
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8ff43046e63c1fdd3c22935ab03f6fc
https://ora.ox.ac.uk/objects/uuid:205f2ace-2179-4a1d-83eb-1679e3d919ae
https://ora.ox.ac.uk/objects/uuid:205f2ace-2179-4a1d-83eb-1679e3d919ae
Autor:
Alberto Auricchio, Elena Marrocco, Pasquale Piccolo, Robin J. Parks, Stefano Colloca, Giulia Cesi, Sarah Jacca, Gaetano Donofrio, Dmitry M. Shayakhmetov, Agostina Puppo, Nicola Brunetti-Pierri, Beverly L. Davidson, Philip Ng
Publikováno v:
Gene Therapy
Gene therapy
Gene therapy
Retinal gene therapy with adeno-associated viral (AAV) vectors is safe and effective in humans. However, the limited cargo capacity of AAV prevents their use for therapy of those inherited retinopathies (IRs) due to mutations in large (>5 kb) genes.
Autor:
Stefano Colloca, Riccardo Cortese, Alfredo Nicosia, Adrian V. S. Hill, Antonella Folgori, Christine S. Rollier, M. Naddeo, Stefania Capone, Virginia Ammendola, Arturo Reyes-Sandoval, Loredana Siani
Malaria is a major health problem as nearly half of the human population is exposed to this parasite causing around 600 million clinical cases annually. Prime-boost regimes using simian adenoviral vectors and MVA expressing the clinically relevant Pl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d07149c81770b9c7ebb595e6617878d
https://ora.ox.ac.uk/objects/uuid:228d1ebb-923b-406d-88d7-6668176037a0
https://ora.ox.ac.uk/objects/uuid:228d1ebb-923b-406d-88d7-6668176037a0
Protective CD8(+) T-cell immunity to human malaria induced by chimpanzee adenovirus-MVA immunisation
Autor:
Adrian V. S. Hill, Sarah C. Gilbert, Loredana Siani, Rhea J. Longley, Alison M. Lawrie, Rosalind Rowland, Katharine A. Collins, Christopher J A Duncan, Riccardo Cortese, Sarah Moyle, Sean C. Elias, Alfredo Nicosia, Fenella D. Halstead, Ian D. Poulton, Eleanor Berrie, Nick J. Edwards, Geraldine O'Hara, Susanne H. Sheehy, Robert E. Sinden, Anna L. Goodman, Antonella Folgori, Arturo Reyes-Sandoval, Nicola Williams, Simon J. Draper, Andrew M. Blagborough, Stefano Colloca, Katie J. Ewer
Publikováno v:
Nature Communications
Induction of antigen-specific CD8+ T cells offers the prospect of immunization against many infectious diseases, but no subunit vaccine has induced CD8+ T cells that correlate with efficacy in humans. Here we demonstrate that a replication-deficient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13a9c7c03e680c56eeb8216d990a9448
http://hdl.handle.net/10044/1/31219
http://hdl.handle.net/10044/1/31219
Autor:
Virginia Ammendola, Riccardo Cortese, Stefania Capone, Alfredo Nicosia, Stefano Colloca, Anna Morena D'Alise, Antonella Folgori
Replication-defective chimpanzee adenovirus vectors are emerging as a promising new class of genetic vaccine carriers. Chimpanzee adenovirus vectors have now reached the clinical stage and appear to be endowed with all the properties needed for human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ebe76cc1b20d8b1a8807e586d2b2a4b
http://hdl.handle.net/11588/571650
http://hdl.handle.net/11588/571650
Autor:
Simon J. Draper, Arturo Reyes-Sandoval, Riccardo Cortese, Antonella Folgori, Adrian V. S. Hill, Sarah C. Gilbert, Alfredo Nicosia, Geraldine O'Hara, Katie J. Ewer, Stefano Colloca, Anna L. Goodman, Alison M. Lawrie
Publikováno v:
Europe PubMed Central
The difficulty of inducing protective immunity through antibodies against sporozoites led to efforts to assess vectored vaccines as a means of inducing protective T-cell immunity against the malaria liver-stage parasite. Although DNA vectored vaccine
Autor:
Antonella Folgori, Alfredo Nicosia, Barbara Rehermann, Stefania Capone, Riccardo Cortese, Stefano Colloca, Eui-Cheol Shin
Publikováno v:
Journal of virology. 82(19)
Peripheral blood T-cell responses are used as biomarkers in hepatitis C virus (HCV) vaccine trials. However, it is not clear how T-cell responses in the blood correlate with those in the liver, the infection site. By studying serial liver and blood s
Autor:
Simon J. Draper, Sumi Biswas, Edmond J. Remarque, Matthew D. J. Dicks, Adrian V. S. Hill, Sarah C. Gilbert, Loredana Siani, Stefano Colloca, Carole A. Long, Matthew G. Cottingham, Anthony A. Holder
Publikováno v:
PLoS ONE
PLoS ONE, Vol 6, Iss 6, p e20977 (2011)
PLoS ONE, Vol 6, Iss 6, p e20977 (2011)
Background Apical membrane antigen 1 (AMA1) is a leading candidate vaccine antigen against blood-stage malaria, although to date numerous clinical trials using mainly protein-in-adjuvant vaccines have shown limited success. Here we describe the pre-c